Patents by Inventor Terence James Ward

Terence James Ward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-(piperidinyl-1-alkyl)-substituted cyclohexane carboxylic acid amides as 5-htia receptor antagonists
    Patent number: 5763460
    Abstract: Compounds of formula (I) and the pharmaceutically acceptable acid addition salts thereof are 5-HT.sub.1A binding agents and may be used, for example, as anxiolytics. In the formula a and b each represents 0, 1, 2 or 3 such that the sum of a+b is 0, 1, 2 or 3, the dotted line represents an optional double bond which may be present in the ring, provided that a is at least 1, A is an alkylene chain of 1 or 2 carbon atoms optionally substituted by one or more lower alkyl groups, R is a mono or bicyclic aryl or heteroaryl radical with the proviso that R is not an unsubstituted phenyl group, R.sup.1 is a mono or bicyclic heteroaryl radical, and R.sup.2 is cycloalkyl or cycloalkenyl.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: June 9, 1998
    Assignees: John Wyeth & Brother Limited, American Home Products Corporation
    Inventors: Ian Anthony Cliffe, Terence James Ward, Chapman White Alan, Antony Ashwell Mark, Bernhard Baudy Reinhardt
  • Piperazine derivatives as 5-HT.sub.1A ligands
    Patent number: 5693642
    Abstract: Piperazine derivatives of formula (I) and their salts are 5-HT.sub.1A binding agents and may be used, for example, as anxiolytics. In the formula, R, R.sup.2 and R.sup.4 are hydrogen or lower alkyl, R.sup.1 is mono- or bicyclic aryl or heteroaryl, R.sup.3 is lower alkyl or cycloalkyl, A is an alkylene chain and X is --CO--. --CR.sup.5 OH-- (where R.sup.5 is hydrogen, lower alkyl or cycloalkyl), --S--, --SO-- or --SO.sub.2 -- or X can also be --(CH.sub.2).sub.n -- (where n is 0, 1 or 2) when R.sup.3 is cycloalkyl.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: December 2, 1997
    Assignee: John Wyeth & Brother Ltd.
    Inventors: Ian Anthony Cliffe, Mark Antony Ashwell, Terence James Ward, Alan Chapman White, Graham John Warrellow
  • 1,4-Dihydro-3,5-pyridine dicarbonitrile derivatives
    Patent number: 3973025
    Abstract: The invention relates to 3,5-dicyano-1,4-dihydro-2,6-di(lower)alkyl-4-methyl-4-phenylpyridines which have hypotensive activity.
    Type: Grant
    Filed: April 29, 1975
    Date of Patent: August 3, 1976
    Assignee: John Wyeth and Brother Limited
    Inventor: Terence James Ward