Patents by Inventor Terence K. Lee

Terence K. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150031744
    Abstract: The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-?N, and inhibitors of CPE-?N and compositions thereof.
    Type: Application
    Filed: July 22, 2014
    Publication date: January 29, 2015
    Inventors: Yoke Peng Loh, Niamh X. Cawley, Saravana Radha Krishna Murthy, Terence K. Lee
  • Patent number: 8816059
    Abstract: The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-?N, and inhibitors of CPE-?N and compositions thereof.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: August 26, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Yoke-peng Loh, Niamh X. Cawley, Saravana Radha Krishna Murthy, Terence K. Lee
  • Publication number: 20110152355
    Abstract: The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-?N, and inhibitors of CPE-?N and compositions thereof.
    Type: Application
    Filed: January 14, 2011
    Publication date: June 23, 2011
    Applicants: Human Services
    Inventors: Yoke-peng Loh, Niamh X. Cawley, Saravana Radha Krishna Murthy, Terence K. Lee