Patents by Inventor Teresa Martinelli

Teresa Martinelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation of fibrinogen from plasma proteases
    Patent number: 6960463
    Abstract: The present invention relates to methods for purifying fibrinogen. In one aspect, the present invention relates to a method of separating fibrinogen from plasma fraction I precipitate. In another aspect, the invention relates to the purification of fibrinogen using ion exchange chromatography.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: November 1, 2005
    Assignee: CSL Limited
    Inventors: Jerry Kanellos, Michael Kleinig, Teresa Martinelli
  • Mannose binding lectin and uses thereof
    Publication number: 20050037949
    Abstract: The present inventors have shown that MASP-depleted MBL is able to recruit MASPs from plasma and successfully activate complement cascade. Furthermore, it has been discovered that MBL purified as a complex has limited ability to activate the complement cascade when compared to MASP-depleted MBL. Accordingly, the present invention provides a pharmaceutical composition comprising an isolated non-recombinant mannose binding lectin (MBL) substantially free from activated MBL associated serine proteases (MASPs) together with a pharmaceutically acceptable carrier or diluent. Also provided is a method of treating a subject in need of MBL comprising administering to the subject an effective amount of a pharmaceutical composition of the invention.
    Type: Application
    Filed: April 24, 2003
    Publication date: February 17, 2005
    Inventors: Grace O'Brien, Robert Pike, Melinda Dean, Robyn Minchinton, Teresa Martinelli
  • Purification of fibrinogen
    Patent number: 6815535
    Abstract: Method of obtaining a fibrinogen enriched preparation by (i) adding an effective amount of a sulphated polysaccharide (SPS) to a fibrinogen containing solution to form a fibrinogen containing precipitate and (ii) extracting fibrinogen from the fibrinogen containing precipitate from step (i) with a solution containing at least 0.1M salt to obtain a fibrinogen enriched preparation.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: November 9, 2004
    Assignee: CSL Limited
    Inventors: Jerry Kanellos, Teresa Martinelli, Grace Demaria, Neil Goss
  • Separation of fibrinogen from plasma proteases
    Publication number: 20030211591
    Abstract: The present invention relates to methods for purifying fibrinogen. In one aspect, the present invention relates to a method of separating fibrinogen from plasma fraction I precipitate. In another aspect, the invention relates to the purification of fibrinogen using ion exchange chromatography.
    Type: Application
    Filed: August 30, 2002
    Publication date: November 13, 2003
    Inventors: Jerry Kanellos, Michael Kleinig, Teresa Martinelli