Patents by Inventor Teresa Sunyer

Teresa Sunyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7115378
    Abstract: A method for identifying and quantifying peptides resulting from enzyme cleavage of collagen type II by mass spectrometric analysis to detect characteristic peptide fragments of a carboxy-terminus having known mass to charge ratios to identify the peptide having that carboxy-terminus. Identification and quantification of the peptides in a biological sample is used to assess activity of proteolytic enzymes in diseases or physiological conditions such as osteoarthritis and rheumatoid arthritis and to assess the efficacy of enzyme blocking agents.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: October 3, 2006
    Assignee: Pharmacia Corporation
    Inventors: Dean J. Welsch, Kevin L. Duffin, Olga V. Nemirovskiy, Dawn R. Dufield, Teresa Sunyer, Carol Pearcy Howard
  • Publication number: 20030219843
    Abstract: A method of determining the concentration of peptides in a biological fluid resulting from the proteolytic degradation of extracellular matrix proteins for diagnosing growth disorders in vertebrates. The method includes determining the concentration of peptides resulting from the proteolytic degradation of extracellular matrix proteins in a biological fluid for determining the efficacy of drugs or agents used to treat growth disorders. A kit for determining the concentration of peptides resulting from the proteolytic degradation of extracellular matrix proteins is also disclosed.
    Type: Application
    Filed: December 20, 2002
    Publication date: November 27, 2003
    Inventors: Dean J. Welsch, Kevin L. Duffin, Olga V. Nemirovskiy, Dawn R. Dufield, Teresa Sunyer, Carol P. Howard, Mark Abrams
  • Publication number: 20030054426
    Abstract: A method for identifying and quantifying peptides resulting from enzyme cleavage of collagen type II by mass spectrometric analysis to detect characteristic peptide fragments of a carboxy-terminus having known mass to charge ratios to identify the peptide having that carboxy-terminus. Identification and quantification of the peptides in a biological sample is used to assess activity of proteolytic enzymes in diseases or physiological conditions such as osteoarthritis and rheumatoid arthritis and to assess the efficacy of enzyme blocking agents.
    Type: Application
    Filed: August 30, 2002
    Publication date: March 20, 2003
    Inventors: Dean J. Welsch, Kevin L. Duffin, Olga V. Nemirovskiy, Dawn R. Dufield, Teresa Sunyer, Carol Pearcy Howard
  • Publication number: 20030049715
    Abstract: A method for identifying and quantifying peptides resulting from enzyme cleavage of collagen type II by mass spectrometric analysis to detect characteristic peptide fragments of a carboxy-terminus having known mass to charge ratios to identify the peptide having that carboxy-terminus. Identification and quantification of the peptides in a biological sample is used to assess activity of proteolytic enzymes in diseases or physiological conditions such as osteoarthritis and rheumatoid arthritis and to assess the efficacy of enzyme blocking agents.
    Type: Application
    Filed: September 3, 2002
    Publication date: March 13, 2003
    Inventors: Dean J. Welsch, Kevin L. Duffin, Olga V. Nemirovskiy, Dawn R. Dufield, Teresa Sunyer, Carol Pearcy Howard