Abstract: A system and apparatus are disclosed for preparing tubular prostheses from a sheet of tissue and inner and outer helical frame components. The tissue is wrapped around the inner frame component over an assembly mandrel. The outer helical frame component is then transferred from an elongate support over a lead screw, onto the assembly mandrel by rotating the assembly mandrel and lead screw in a manner which positions the outer helical frame component in an appropriate manner. Optionally, the mandrel is collapsed to facilitate removal of the completed tubular prosthesis.

Abstract: A system and apparatus are disclosed for preparing tubular prostheses from a sheet of tissue and inner and outer helical frame components. The tissue is wrapped around the inner frame component over an assembly mandrel. The outer helical frame component is then transferred from an elongate support over a lead screw, onto the assembly mandrel by rotating the assembly mandrel and lead screw in a manner which positions the outer helical frame component in an appropriate manner. Optionally, the mandrel is collapsed to facilitate removal of the completed tubular prosthesis.

Abstract: The present invention provides a novel tissue cutting device which accurately cuts the tissue to a predetermined configuration in a minimal amount of time, and where the tissue may then be used in an autologous heart valve. The disposable tissue cutting die of the present invention is comprised of a cutting die assembly and a cutting base assembly. The cutting die assembly retains a continuous blade with razor sharpened edges that enclose a desired spatial configuration. The cutting base assembly includes a rotatable cutting pad on which the tissue to be cut may be placed. The cutting die assembly and cutting base assembly are adpated to cooperate to cut the tissue when the cutting die assembly is inserted into the cutting base assembly and rotated approximately 180 degrees.

Abstract: A centrifugal blood pump having a pumping chamber provided with an axial inlet and a circumferential outlet and provided with a rotatable impeller having a plurality of radially extending blood propelling vanes. The vanes are configured to each have a blade angle which varies monotonically toward the periphery of the chamber. The pumping chamber is delimited by an impeller housing provided with an opening through which the impeller shaft extends into the chamber, the opening having an outline which conforms closely to the outline of the shaft, and the pump further includes a bearing housing secured to the impeller housing and delimiting a bearing chamber into which the shaft extends; bearings disposed in the bearing chamber and rotatably supporting the shaft; and a seal located in the bearing chamber adjacent the opening and surrounding the shaft to form a fluid seal between the blood pumping chamber and the bearing chamber.