Patents by Inventor Terrence Howell

Terrence Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070202208
    Abstract: The invention provides hops (Humulus lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type chemically induced, environmentally-induced, infection-induced, and/or stress-induced. The invention also provides a pharmaceutical composition comprising an active amount of hops extracts or derivatives thereof, in combination with an analgesic compound and/or an anti-inflammatory compound. The invention further provides for use of hops extracts or derivatives thereof, significantly reducing and/or therapeutically treating ulcerogenic-type disorders of the stomach and/or intestines.
    Type: Application
    Filed: May 21, 2004
    Publication date: August 30, 2007
    Inventors: John Babish, Matthew Tripp, Terrence Howell, Jeffrey Bland, Gary Darland, Robert Leman, Daniel Lukaczer
  • Publication number: 20070184133
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: March 29, 2007
    Publication date: August 9, 2007
    Applicant: Metaproteomics, LLC
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20070160692
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: October 20, 2003
    Publication date: July 12, 2007
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20070141183
    Abstract: A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a curcuminoid species and an effective amount of a second component selected from the group consisting of an alpha-acid species or a beta-acid species or derivatives thereof. The composition provides synergistic anti-inflammatory effects in response to physical or chemical injury or abnormal immune stimulation due to a biological agent or unknown etiology.
    Type: Application
    Filed: February 2, 2007
    Publication date: June 21, 2007
    Applicant: Metaproteomics, LLC
    Inventors: John Babish, Terrence Howell, Linda Pacioretty
  • Patent number: 7205151
    Abstract: A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective amount of at least one component II selected from the group consisting of alpha acids, beta acids, essential oils, fats and waxes, with the proviso that component I and II are not the same compound. The composition provides specific inhibition of cyclooxygenase-2 with little or no effect on cyclooxygenase-1.
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: April 17, 2007
    Assignee: Metaproteomics, LLC
    Inventors: John G. Babish, M. Terrence Howell
  • Publication number: 20060193933
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.
    Type: Application
    Filed: April 12, 2006
    Publication date: August 31, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060177531
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: April 12, 2006
    Publication date: August 10, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060141082
    Abstract: The invention provides hops (Humulis lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type chemically induced, environmentally-induced, infection-induced, and/or stress-induced. The invention also provides a pharmaceutical composition comprising an active amount of hops extracts or derivatives thereof, in combination with an analgesic compound and/or an anti-inflammatory compound. The invention further provides for use of hops extracts or derivatives thereof, significantly reducing and/or therapeutically treating ulcerogenic-type disorders of the stomach and/or intestines.
    Type: Application
    Filed: February 15, 2006
    Publication date: June 29, 2006
    Inventors: John Babish, Matthew Tripp, Jeffrey Bland, Terrence Howell, Gary Darland, Robert Lerman, Daniel Lukaczer
  • Publication number: 20060141081
    Abstract: The invention provides hops (Humulus lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type chemically induced, environmentally-induced, infection-induced, and/or stress-induced. The invention also provides a pharmaceutical composition comprising an active amount of hops extracts or derivatives thereof, in combination with an analgesic compound and/or an anti-inflammatory compound. The invention further provides for use of hops extracts or derivatives thereof, significantly reducing and/or therapeutically treating ulcerogenic-type disorders of the stomach and/or intestines.
    Type: Application
    Filed: February 15, 2006
    Publication date: June 29, 2006
    Inventors: John Babish, Matthew Tripp, Jeffrey Bland, Terrence Howell, Gary Darland, Robert Lerman, Daniel Lukaczer
  • Publication number: 20060127512
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127511
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127513
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127516
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127514
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127517
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Publication number: 20060127515
    Abstract: A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 15, 2006
    Inventors: Matthew Tripp, John Babish, Jeffrey Bland, Gary Darland, Robert Lerman, Daniel Lukaczer, DeAnn Liska, Terrence Howell
  • Patent number: 6979470
    Abstract: Compositions comprising an effective amount of a curcuminoid species and an effective amount of a diterpene lactone species, a triterpene species or derivatives thereof that have a synergistic effect on specific inhibition of inducible COX-2 activity and have minimal effect on COX-1 activity are disclosed. Methods of using the compositions for providing synergistic anti-inflammatory effects are also disclosed.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: December 27, 2005
    Assignee: Metaproteomics, LLC
    Inventors: John G. Babish, Terrence Howell, Linda Pacioretty
  • Patent number: 6908630
    Abstract: A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a diterpene triepoxide lactone species and an effective amount of a second component of a sesquiterpene lactone species or derivatives thereof, and provides synergistic anti-inflammatory effects in response to physical or chemical injury or abnormal immune stimulation due to a biological agent or unknown etiology.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: June 21, 2005
    Assignee: Metaproteomics, LLC
    Inventors: John G. Babish, Terrence Howell, Linda Pacioretty
  • Publication number: 20050129791
    Abstract: A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a curcuminoid species and an effective amount of a second component selected from the group consisting of an alpha-acid species or a beta-acid species or derivatives thereof. The composition provides synergistic anti-inflammatory effects in response to physical or chemical injury or abnormal immune stimulation due to a biological agent or unknown etiology.
    Type: Application
    Filed: November 13, 2004
    Publication date: June 16, 2005
    Inventors: John Babish, Terrence Howell, Linda Pacioretty
  • Patent number: D537381
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: February 27, 2007
    Inventor: Terrence Howell