Abstract: A magnetic resonance imaging system may include a magnet, gradient coils, an RF pulse transmitter, an RF receiver that receives MR signals from tissue that has been exposed to RF pulses, gradient fields, and a magnetic field, and a computer that includes a processor. The computer may have a configuration that: causes the RF pulse transmitter and gradient coils to emit multiple labeling pulses at predetermined labeling times directed to blood in a subject; causes the RF pulse transmitter, gradient coils, and magnet to generate MR signals directed to tissue at one or more spatial locations within the subject that receives the blood; causes the RF receiver to receive MR signals emitted by the tissue at predetermined imaging times; generates an image of the tissue based on the received MR signals; repeats the foregoing four actions one or more times; and generates information indicative of perfusion within the tissue based on the generated images.

Abstract: Image processing methods are described that include segmenting boundaries of a region of interest (ROI) and identifying one or more control points, in each of multiple images of the same object, region, or location. The coordinates of each image are transformed from image coordinates into a coordinate frame relative to the control point or points. Image data is resampled and filtered and/or averaged. One or more material properties can be calculated from the resampled and filtered image data and then displayed. Alignment of unregistered image data of multiple images of the same object, region, or location is provided. Applications are described for medical imaging.