Patents by Inventor Terri H. Finkel

Terri H. Finkel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXR4 as a susceptibility locus in juvenile idiopathic arthritis (JIA) and methods of use thereof for the treatment and diagnosis of the same
    Patent number: 11499194
    Abstract: Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: November 15, 2022
    Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Terri H. Finkel, Haitao Zhang, Hakon Hakonarson
  • CXR4 as a Susceptibility Locus in Juvenile Idiopathic Arthritis (JIA) and Methods of Use Thereof for the Treatment and Diagnosis of the Same
    Publication number: 20190309366
    Abstract: Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
    Type: Application
    Filed: May 16, 2019
    Publication date: October 10, 2019
    Inventors: Terri H. Finkel, Haitao Zhang, Hakon Hakonarson
  • CXCR4 as a susceptibility locus in juvenile idiopathic arthritis (JIA) and methods of use thereof for the treatment and diagnosis of the same
    Patent number: 10344331
    Abstract: Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: July 9, 2019
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Haitao Zhang, Hakon Hakonarson
  • CXR4 as a Susceptibility Locus in Juvenile Idiopathic Arthritis (JIA) and Methods of Use Thereof for the Treatment and Diagnosis of the Same
    Publication number: 20160348177
    Abstract: Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
    Type: Application
    Filed: August 10, 2016
    Publication date: December 1, 2016
    Inventors: Terri H. Finkel, Haitao Zhang, Hakon Hakonarson
  • Compositions comprising a Brd4 antagonist and methods for the treatment of HIV
    Patent number: 9387231
    Abstract: Compositions and methods for the treatment of HIV are provided.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: July 12, 2016
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiangfang Wang, Gerd Blobel, Stephan Kadauke
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF HIV
    Publication number: 20140199260
    Abstract: Compositions and methods for the treatment of HIV are provided.
    Type: Application
    Filed: January 29, 2014
    Publication date: July 17, 2014
    Inventors: Terri H. Finkel, Jiangfang Wang, Gerd Blobel, Stephan Kadauke
  • CXCR4 as a Susceptibility Locus in Juvenile Idiopathic Arthritis (JIA) and Methods of Use Thereof for the Treatment and Diagnosis of the Same
    Publication number: 20130315931
    Abstract: Compositions and methods useful for the diagnosis and treatment of juvenile idiopathic arthritis are disclosed.
    Type: Application
    Filed: May 13, 2013
    Publication date: November 28, 2013
    Inventors: Terri H. Finkel, Haitao Zhang, Hakon Hakonarson
  • Cellular genes regulated by HIV-1 infection and methods of use thereof
    Patent number: 8334275
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: December 18, 2012
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiyi Yin
  • Cellular Genes Regulated by HIV-1 Infection and Methods of Use Thereof
    Publication number: 20120022136
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
    Type: Application
    Filed: June 24, 2011
    Publication date: January 26, 2012
    Applicant: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiyi Yin
  • Cellular genes regulated by HIV-1 infection and methods of use thereof
    Patent number: 7994147
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: August 9, 2011
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiyi Yin
  • CELLULAR GENES REGULATED BY HIV-1 INFECTION AND METHODS OF USE THEREOF
    Publication number: 20080293663
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
    Type: Application
    Filed: July 14, 2008
    Publication date: November 27, 2008
    Inventors: Terri H. Finkel, Jiyi Yin
  • Cellular genes regulated by HIV-1 infection and methods of use thereof
    Patent number: 7405292
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: July 29, 2008
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiyi Yin
  • Cellular genes regulated by HIV-1 infection and methods of use thereof
    Patent number: 7288644
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells. Other pro-apoptotic genes and methods of use thereof are also disclosed. The compositions of the invention may be used to advantage to develop novel therapeutic agents for the treatment of HIV infection. The compositions of the invention may also be used to advantage to develop novel therapeutic agents for the treatment of disorders associated with inordinate cellular apoptosis.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: October 30, 2007
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Terri H. Finkel, Jiyi Yin
  • Fluid planar lipid layer-based membrane-anchored ligand system with defined ligand valency and methods of use thereof
    Publication number: 20040219605
    Abstract: Fluid planar lipid layer-based membrane-anchored ligand systems with defined ligand valency and methods of use thereof are provided.
    Type: Application
    Filed: April 8, 2004
    Publication date: November 4, 2004
    Inventors: Terri H. Finkel, Zhengyu Ma
  • Methods and compositions for increasing CD4lymphocyte immune responsiveness
    Publication number: 20040132161
    Abstract: This invention identifies the cellular gene STAT5 as modulating the HIV-1 life cycle in infected cells. Compositions and methods are provided as novel means for the treatment of HIV infection.
    Type: Application
    Filed: September 29, 2003
    Publication date: July 8, 2004
    Inventors: Terri H. Finkel, Nithianandan Selliah, Dennis C. DeSimone, Randall Q. Cron
  • Method and composition for increasing CD4+ T lymphocyte immune responsiveness
    Publication number: 20030232738
    Abstract: A method and composition to restore and/or increase immune responsiveness in CD4+ T lymphocytes that display a loss of immune function (i.e., immune unresponsiveness) after CD4 is ligated by human immunodeficiency virus (HIV) gp120 are disclosed. Such a method and composition are useful for restoring immune surveillance and host defense capabilities to an HIV-infected patient, for causing HIV-infected T lymphocytes to become targets of the immune system, and for increasing the survival and development of CD4+ T lymphocytes in HIV-infected patients so the immune system can be reconstituted. Also disclosed are a method to identify putative regulatory compounds useful in a composition of the invention and a method to identify suitable candidate patients for treatment by a method of the invention.
    Type: Application
    Filed: December 5, 2002
    Publication date: December 18, 2003
    Applicant: National Jewish Medical and Research Center
    Inventors: Terri H. Finkel, Nithianandan Selliah
  • Cellular genes regulated by HIV-1 infection and methods of use thereof
    Publication number: 20030219728
    Abstract: This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells. Other pro-apoptotic genes and methods of use thereof are also disclosed. The compositions of the invention may be used to advantage to develop novel therapeutic agents for the treatment of HIV infection. The compositions of the invention may also be used to advantage to develop novel therapeutic agents for the treatment of disorders associated with inordinate cellular apoptosis.
    Type: Application
    Filed: February 19, 2003
    Publication date: November 27, 2003
    Inventors: Terri H. Finkel, Jiyi Yin
  • Product and process to regulate actin polymerization in T lymphocytes
    Publication number: 20030143644
    Abstract: The present invention relates to methods to regulate actin polymerization in T lymphocytes involved in tumorigenesis, inflammatory responses, immune responses, allergic responses and graft rejection responses, kits to perform such assays and methods to identify regulatory reagents that specifically control actin polymerization in T lymphocytes.
    Type: Application
    Filed: December 31, 2002
    Publication date: July 31, 2003
    Applicant: National Jewish Medical and Research Center
    Inventors: Terri H. Finkel, Moshe M. Rozdzial
  • Product and process to regulate actin polymerization in T lymphocytes
    Patent number: 6500430
    Abstract: The present invention relates to methods to regulate actin polymerization in T lymphocytes involved in tumorigenesis, inflammatory responses, immune responses, allergic responses and graft rejection responses, kits to perform such assays and methods to identify regulatory reagents that specifically control actin polymerization in T lymphocytes.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: December 31, 2002
    Assignee: National Jewish Medical and Research Center
    Inventors: Terri H. Finkel, Moshe M. Rozdzial
  • Method to limit immunodeficiency virus infection and compounds therefor
    Publication number: 20020091073
    Abstract: Disclosed is a method to limit infection by an immunodeficiency virus. The method includes inhibiting an immunodeficiency virus protein which regulates apoptosis in cells. Also disclosed are methods to identify compounds that regulate cellular inhibitors of apoptosis in cells infected with an immunodeficiency virus and compounds identified thereby.
    Type: Application
    Filed: June 13, 2001
    Publication date: July 11, 2002
    Applicant: National Jewish Medical and Research Center
    Inventors: Terri H. Finkel, Carolyn Casella