Abstract: A tool configured to apply a lubricant includes an insert disposed within a shroud of an electrical connector. The insert has a central cavity and passages extending from the central cavity to portals defined in an outer surface of the insert and a spray valve disposed within the insert configured to dispense a lubricant mist into the central cavity, through the passages to the portals, and onto a seal wiping surface of the electrical connector.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: A tool configured to apply a lubricant includes an insert disposed within a shroud of an electrical connector. The insert has a central cavity and passages extending from the central cavity to portals defined in an outer surface of the insert and a spray valve disposed within the insert configured to dispense a lubricant mist into the central cavity, through the passages to the portals, and onto a seal wiping surface of the electrical connector.

Abstract: A method of preparing a sealed connector system for connection is presented. The sealed connector system has a male connector body, a female connector body defining a shroud to receive the male connector body, and a resilient seal surrounding the male connector body. The method includes the steps of applying lubricant on a seal wiping surface on the shroud interior and inserting the male connector body within the female connector body such that the resilient seal is in compressive contact with the seal wiping surface. A tool to apply the lubricant includes an insert disposed within the shroud having a central cavity and passages extending from the central cavity to portals defined in an outer surface of the insert and a spray valve disposed within the insert configured to dispense a lubricant mist into the central cavity, through the passages to the portals, and onto the seal wiping surface.

Abstract: A medical device includes an inflatable balloon defining an interior surface and an exterior surface, and a coating including a therapeutic agent disposed on the exterior surface of the inflatable balloon. The coating has a release transition temperature within a range from about 25° C. to about 50° C. When the temperature of the coating is below the release transition temperature, the coating retains at least a portion of the therapeutic agent on the exterior of the inflatable balloon. When the temperature of the coating is above the release transition temperature, the coating releases at least a portion of the therapeutic agent from the exterior of the inflatable balloon.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: A method of preparing a sealed connector system for connection is presented. The sealed connector system has a male connector body, a female connector body defining a shroud to receive the male connector body, and a resilient seal surrounding the male connector body. The method includes the steps of applying lubricant on a seal wiping surface on the shroud interior and inserting the male connector body within the female connector body such that the resilient seal is in compressive contact with the seal wiping surface. A tool to apply the lubricant includes an insert disposed within the shroud having a central cavity and passages extending from the central cavity to portals defined in an outer surface of the insert and a spray valve disposed within the insert configured to dispense a lubricant mist into the central cavity, through the passages to the portals, and onto the seal wiping surface.

Abstract: The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

Abstract: A medical device includes an inflatable balloon defining an interior surface and an exterior surface, and a coating including a therapeutic agent disposed on the exterior surface of the inflatable balloon. The coating has a release transition temperature within a range from about 25° C. to about 50° C. When the temperature of the coating is below the release transition temperature, the coating retains at least a portion of the therapeutic agent on the exterior of the inflatable balloon. When the temperature of the coating is above the release transition temperature, the coating releases at least a portion of the therapeutic agent from the exterior of the inflatable balloon.

Abstract: A terminal assembly configured to terminate the shield of a shielded cable having an inner conductor, an inner insulator surrounding the inner conductor, an outer conductor forming a shield surrounding the inner insulator, and an outer insulator surrounding the outer conductor. The terminal assembly includes a generally cylindrical outer ferrule formed of a conductive material and a generally cylindrical inner ferrule formed of a resilient compressible dielectric material. At least a portion of the inner ferrule is disposed within the outer ferrule and a portion of the shielded cable is disposed within the inner ferrule. A portion of the outer conductor is disposed intermediate the inner and outer ferrules and is in intimate contact therewith.

Abstract: A battery pack assembly has a plurality of interconnected battery cells and is suitable for use in an electric vehicle or a hybrid electric vehicle. The assembly includes a first battery cell having a first terminal and a second battery cell having a second terminal electrically interconnected by a bus bar formed of a conductive material and attached to the first terminal and the second terminal. A bus bar retainer formed of a dielectric material is configured to contain the bus bar within the bus bar retainer. The bus bar has a greater freedom of movement within the bus bar retainer along a first, e.g. vertical, axis than along a second, e.g. longitudinal, axis and a third, e.g. lateral axis, wherein both the second and third axes are substantially perpendicular to the first axis and to each other. The assembly may also include individually removable temperature sensing devices.

Abstract: A battery pack assembly has a plurality of interconnected battery cells and is suitable for use in an electric vehicle or a hybrid electric vehicle. The assembly includes a first battery cell having a first terminal and a second battery cell having a second terminal electrically interconnected by a bus bar formed of a conductive material and attached to the first terminal and the second terminal. A bus bar retainer formed of a dielectric material is configured to contain the bus bar within the bus bar retainer. The bus bar has a greater freedom of movement within the bus bar retainer along a first, e.g. vertical, axis than along a second, e.g. longitudinal, axis and a third, e.g. lateral axis, wherein both the second and third axes are substantially perpendicular to the first axis and to each other. The assembly may also include individually removable temperature sensing devices.

Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

Abstract: The present invention relates to a method for screening drugs for use in treating hypertension using the tubular renin-angiotensinogen system identified by the present invention. The invention further relates to a method to diagnose sodium status and sensitivity in an individual by measuring urinary angiotensinogen or angiotensin-I.

Abstract: A gearbox actuator comprising a selector shaft 2 which is arranged in a housing and is driven by a drive. A shift finger 3 and disengaging shaped elements 4 used to actuate gearshift rails are arranged on the selector shaft, and jibs for 12-15 supporting and guiding the gearshift rails are arranged on the housing. The gearbox actuator 1 comprises the central selector shaft 2 mounted in bearing elements 19 and comprises a shift finger 3 and two disengaging shaped elements 4 arranged in the center thereof, at a distance corresponding to the width of a channel. Preferably, the selector shaft 2 is driven by a brushless motor 5 by means of a double planetary stage 6 and a toothed segment 7 which engages a toothed wheel 16 that is preferably positioned in a housing element 17. A preferably second brushless motor 8 drives a sliding element 37 by means of spindle 9, the sliding element displacing the shift finger 3 and the disengaging shaped elements 4 on the selector shaft 2.

Abstract: A gearbox actuator comprising a selector shaft 2 which is arranged in a housing and is driven by a drive. A shift finger 3 and disengaging shaped elements 4 used to actuate gearshift rails are arranged on the selector shaft, and jibs for 12-15 supporting and guiding the gearshift rails are arranged on the housing. The gearbox actuator 1 comprises the central selector shaft 2 mounted in bearing elements 19 and comprises a shift finger 3 and two disengaging shaped elements 4 arranged in the center thereof, at a distance corresponding to the width of a channel. Preferably, the selector shaft 2 is driven by a brushless motor 5 by means of a double planetary stage 6 and a toothed segment 7 which engages a toothed wheel 16 that is preferably positioned in a housing element 17. A preferably second brushless motor 8 drives a sliding element 37 by means of spindle 9, the sliding element displacing the shift finger 3 and the disengaging shaped elements 4 on the selector shaft 2.

Abstract: The present invention relates to a method for screening drugs for use in treating hypertension using the tubular renin-angiotensinogen system identified by the present invention. The invention further relates to a method to diagnose sodium status and sensitivity in an individual by measuring urinary angiotensinogen or angiotensin-I.

Abstract: The present invention relates to a method for screening drugs for use in treating hypertension using the tubular renin-angiotensinogen system identified by the present invention. The invention further relates to a method to diagnose sodium status and sensitivity in an individual by measuring urinary angiotensinogen or angiotensin-I.