Patents by Inventor Terry Barton Strom

Terry Barton Strom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TIM-3 ligands and methods of modulating immune responses
    Patent number: 9346876
    Abstract: The invention relates to isolated polypeptides and nucleic acids encoding polypeptides which comprise a tim-3 IgV domain and a tim-3 intracellular domain, wherein the polypeptides do not comprise a tim-3 mucin domain or a tim-3 transmembrane domain. In addition, the invention relates to methods of modulating immune responses in a subject, comprising administering to the subject a therapeutically effective amount of an agent that modulates tim-3 activity. Immune responses include, but are not limited to, immune tolerance, transplantation tolerance, Th1 responses and Th2 responses.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: May 24, 2016
    Assignees: The Brigham and Women's Hospital, Inc., Beth Israel Deaconess Medical Center, Inc.
    Inventors: Vijay K. Kuchroo, Terry Barton Strom, Eugene K. Cha, Sumone Chakravarti, Catherine Anne Sabatos-Peyton, Chen Zhu, Xin Xiao Zheng, Alberto Sanchez-Fueyo