Patents by Inventor Terry D. Butters

Terry D. Butters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iminosugars and methods of treating viral diseases
    Patent number: 9943532
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: April 17, 2018
    Assignees: Emergent Virology LLC, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES
    Publication number: 20170304333
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Application
    Filed: January 5, 2017
    Publication date: October 26, 2017
    Applicants: Emergent Virology LLC, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
    Inventors: Urban RAMSTEDT, Brennan KLOSE, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Iminosugars and methods of treating viral diseases
    Patent number: 9579334
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: February 28, 2017
    Assignee: EMERGENT VIROLOGY LLC
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS
    Publication number: 20160243096
    Abstract: Provided are novel iminosugars and methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Orthomyxoviridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: May 4, 2016
    Publication date: August 25, 2016
    Inventors: Urban RAMSTEDT, Brennan KLOSE, Nicole ZITZMANN, Raymond A. DWEK, Terry D. BUTTERS
  • METHODS OF TREATING POXVIRAL INFECTIONS
    Publication number: 20160243097
    Abstract: Provided are methods of treating a disease or condition caused by or associated with a virus belonging to the Poxviridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: May 4, 2016
    Publication date: August 25, 2016
    Inventors: Urban RAMSTEDT, Brennan KLOSE, Nicole ZITZMANN, Raymond A. DWEK, Terry D. BUTTERS
  • IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES
    Publication number: 20150224128
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Application
    Filed: April 27, 2015
    Publication date: August 13, 2015
    Applicants: United Therapeutics Corporation, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Long chain N-alkyl compounds and oxa-derivatives thereof
    Patent number: 9089515
    Abstract: Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: July 28, 2015
    Assignees: Thomas Jefferson University, The Chancellor, Masters and Scholars of the University of Oxford, United Therapeutics Corporation
    Inventors: Nicole Zitzmann, Terry D. Butters, Frances M. Platt, Gary S. Jacob, Donald H. Picker, Sandra Carrouee, George W. J. Fleet, Raymond A. Dwek, David Durantel, Anand Mehta, Timothy M. Block
  • Iminosugars and methods of treating viral diseases
    Patent number: 9044470
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: June 2, 2015
    Assignees: United Therapeutics Corporation, The Chancellor, Masters and Scholars of The University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Deoxynojirimycin and D-arabinitol analogs and methods of using
    Patent number: 8975280
    Abstract: A compound of Formula I are provided: wherein R is: R1 is a substituted or unsubstituted alkyl group; W1-4 are independently selected from hydrogen, substituted or unsubstituted alkyl groups, substituted or unsubstituted haloalkyl groups, substituted or unsubstituted alkanoyl groups, substituted or unsubstituted aroyl groups, or substituted or unsubstituted haloalkanoyl groups; X1-5 are independently selected from H, NO2, N3, and NH2; Y is absent or is a substituted or unsubstituted C1-alkyl group, other than carbonyl; Z is selected from a bond or NH, provided that when Z is a bond, Y is absent, and provided that when Z is NH, Y is a substituted or unsubstituted C1-alkyl group, other than carbonyl. Also provided are D-arabinitol compounds, methods for preparing such compounds and compositions of such compounds, and methods of using such compounds.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: March 10, 2015
    Assignee: The Chancellor, Masters and Scholars of The University of Oxford
    Inventors: Terry D. Butters, Raymond A. Dwek, George W. J. Fleet
  • Iminosugars and methods of treating togaviral diseases
    Patent number: 8748460
    Abstract: Provided are novel methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Togaviridae family using iminosugars, such as DNJ derivatives.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 10, 2014
    Assignees: United Therapeutics Corporation, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • IMINOSUGARS AND METHODS OF TREATING VIRAL DISEASES
    Publication number: 20130237567
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 12, 2013
    Applicants: The Chancellor, Masters and Scholars of the University of Oxford, United Therapeutics Corporation
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Iminosugars and methods of treating viral diseases
    Patent number: 8450345
    Abstract: Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: May 28, 2013
    Assignees: The Chancellor, Masters and Scholars of the University of Oxford, United Therapeutics Corporation
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Iminosugars and methods of treating bunyaviral and togaviral diseases
    Patent number: 8426445
    Abstract: Provided are novel methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Bunyaviridae or Togaviridae family using iminosugars, such as DNJ derivatives.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: April 23, 2013
    Assignees: United Therapeutics Corporation, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Iminosugars and methods of treating bunyaviral and togaviral diseases
    Patent number: 8367705
    Abstract: Provided are novel methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Bunyaviridae or Togaviridae family using iminosugars, such as DNJ derivatives.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: February 5, 2013
    Assignees: United Therapeutics Corporation, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Long chain N-Alkyl compounds and oxa-derivatives thereof
    Publication number: 20110184019
    Abstract: Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.
    Type: Application
    Filed: March 7, 2011
    Publication date: July 28, 2011
    Inventors: Nicole Zitzmann, Terry D. Butters, Frances M. Platt, Gary S. Jacob, Donald H. Picker, Sandra Carrouee, George W. J. Fleet, Raymond A. Dwek, David Durantel, Anand Mehta, Timothy M. Block
  • METHODS OF TREATING ORTHOMYXOVIRAL INFECTIONS
    Publication number: 20110065752
    Abstract: Provided are novel iminosugars and methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Orthomyxoviridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: September 1, 2010
    Publication date: March 17, 2011
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • METHODS OF TREATING POXVIRAL INFECTIONS
    Publication number: 20110065753
    Abstract: Provided are methods of treating a disease or condition caused by or associated with a virus belonging to the Poxyiridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: September 1, 2010
    Publication date: March 17, 2011
    Inventors: Urban Ramstedt, Brennan Kolse, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • IMINOSUGARS AND METHODS OF TREATING FILOVIRAL DISEASES
    Publication number: 20110065754
    Abstract: Provided are methods of treating a disease or condition caused by or associated with a virus belonging to the Filoviridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: September 1, 2010
    Publication date: March 17, 2011
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • IMINOSUGARS AND METHODS OF TREATING BUNYAVIRAL AND TOGAVIRAL DISEASES
    Publication number: 20100317696
    Abstract: Provided are novel methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Bunyaviridae or Togaviridae family using iminosugars, such as DNJ derivatives.
    Type: Application
    Filed: June 11, 2010
    Publication date: December 16, 2010
    Inventors: Urban Ramstedt, Brennan Klose, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
  • Long chain n-alkyl compounds and oxa-derivatives thereof
    Patent number: 7816560
    Abstract: Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: October 19, 2010
    Assignees: Thomas Jefferson University, The Chancellor, Masters and Scholars of the University of Oxford, United Therapeutics Corporation
    Inventors: Nicole Zitzmann, Terry D. Butters, Frances M. Platt, Gary S. Jacob, Donald H. Picker, Sandra Carrouee, George W. J. Fleet, Raymond A. Dwek, David Durantel, Anand Mehta, Timothy M. Block