Abstract: The present innovation is a customized compression device for prevention and treatment of keloids and hypertrophic scarring, primarily a frequent complication of ear piercing. The “one size fits all” design of traditional devices can compromise efficacy due to uneven fit and compression. This invention harnesses 3D digital scanning to capture the intricate contours of the ear for every patient, for personalized compression therapy. Using 3D printing, shells are fabricated with biocompatible materials such as Polylactic Acid, shape memory polymers, or silicone-based substances. In primary embodiments, device functionality is achieved with compression clips or spring-open, single-piece structures. The custom fit, potential for infusion of therapeutic agents (e.g., corticosteroids), and engineered porosity combine to improve keloid management from uniform pressure distribution and optimal healing. Additionally, the ‘shells’ can be pigmented to match patient skin tones and encourage compliance.

Abstract: Described herein are synthetic bait compositions and methods for manufacturing synthetic baits that dissolve instantaneously in aqueous media or over a period of seconds up to about 40 days and attract marine organisms. The synthetic baits utilize chemotactic cues to attract marine organisms.

Abstract: The present invention is directed to a method and apparatus for detection of a diagnostically significant amount of clot in an aliquot of blood. In a preferred embodiment, the method uses a cocktail of activators to facilitate and proctor absolute activation of Factor XII (the contact factor for the intrinsic pathway of coagulation). Possible activators include Celite®, kaolin, glass beads, colloidal silica, and diatomaceous material. This cocktail formulation is important because some individuals respond differently to different activators and hence, the cocktail formulation facilitates standardization of the patient population by reducing the patient-activator sensitivity artifacts.

Abstract: The present invention utilizes a novel reaction chamber. The reaction chamber is made from a pierceable self-sealing material which may be in the form of a long, narrow tube. The may contains a single reagent within the entire length of the tube or the tube may be segmented into a plurality of distinct chambers. Numerous tests can be performed within a given tube, separated either by distance or a physical barrier, with no degradation or interference between the testing sites. The test results may be conveniently determined using any of the known detection methodologies, including photometric, electromechanical, spectrophotometric, and nephlometric detection mechanisms.