Patents by Inventor Terry L. Thomas
Terry L. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7253276Abstract: The invention is directed to isolated promoters from stem-regulated, defense-inducible genes, such as JAS promoters. The promoters are useful in expression cassettes and expression vectors for the transformation of plants. Particularly, the invention provides transgenic plants of rice and sugarcane that have been modified such that expression of a heterologous coding sequence is directed by an JAS promoter and is limited to stem tissues or may be upregulated by the presence of a defense-inducing agent. The invention also discloses methods for producing the expression vectors and transgenic plants.Type: GrantFiled: January 5, 2004Date of Patent: August 7, 2007Assignee: The Texas A&M University SystemInventors: Mona B. Damaj, T. Erik Mirkov, Avutu Reddy, Terry L. Thomas, Keerti S. Rathore, Chandrakanth Emani, Siva Prasad Kumpatla
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Patent number: 7189894Abstract: Linoleic acid is converted into ?-linolenic acid by the enzyme ?6-desaturase. The present invention is directed to isolated nucleic acids comprising the ?6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the ?6-desaturase gene. The present invention provides recombinant constructions comprising the ?6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: December 21, 2001Date of Patent: March 13, 2007Assignee: Rhone-Poulenc AgrochimieInventor: Terry L. Thomas
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Publication number: 20040078845Abstract: Linoleic acid is converted into &ggr;-linolenic acid by the enzyme &Dgr;6-desaturase. The present invention is directed to isolated nucleic acids comprising the &Dgr;6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the &Dgr;6-desaturase gene. The present invention provides recombinant constructions comprising the &Dgr;6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: ApplicationFiled: November 6, 2003Publication date: April 22, 2004Inventor: Terry L. Thomas
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Patent number: 6683232Abstract: Linoleic acid is converted into &ggr;-linolenic acid by the enzyme &Dgr;6-desaturase. The present invention is directed to isolated nucleic acids comprising the &Dgr;6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the &Dgr;6-desaturase gene. The present invention provides recombinant constructions comprising the &Dgr;6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: October 10, 2000Date of Patent: January 27, 2004Assignee: Rhone-Poulenc AgrochimieInventor: Terry L. Thomas
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Publication number: 20020108147Abstract: Linoleic acid is converted into &ggr;-linolenic acid by the enzyme &Dgr;6-desaturase. The present invention is directed to isolated nucleic acids comprising the &Dgr;6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the &Dgr;6-desaturase gene. The present invention provides recombinant constructions comprising the &Dgr;6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: ApplicationFiled: December 21, 2001Publication date: August 8, 2002Inventor: Terry L. Thomas
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Patent number: 6355861Abstract: Linoleic acid is converted into &ggr;-linolenic acid by the enzyme &Dgr;6-desaturase. The present invention is directed to isolated nucleic acids comprising the &Dgr;6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the &Dgr;6-desaturase gene. The present invention provides recombinant constructions comprising the &Dgr;6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: September 19, 1997Date of Patent: March 12, 2002Assignee: Rhone-Poulenc AgrochimieInventor: Terry L. Thomas
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Patent number: 6342657Abstract: The present invention is directed to isolated promoter sequences from seed-specific genes, such as KNAT411. When operably linked to either the coding sequence of a heterologous gene or a sequence complementary to a native plant gene, the subject promoters direct expression of the coding sequence or complementary sequence in a plant seed, including the early embryo. The promoter sequences are useful in expression cassettes and expression vectors for the transformation of plants. Also provided are methods of directing seed-specific expression of a gene or sequence complementary to a native plant gene by introducing into a plant cell an isolated nucleic acid comprising a subject promoter operably linked to said gene or complementary sequence. Methods for activating a site-specific recombination system in the early embryo of a seed by transforming a plant with an expression cassette comprising a subject promoter operably linked to a recombinase gene are also provided.Type: GrantFiled: May 6, 1999Date of Patent: January 29, 2002Assignee: Rhone-Poulenc AgroInventors: Terry L. Thomas, Tzung-Fu Hsieh
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Patent number: 6100450Abstract: The present invention is directed to 5' regulatory regions of two Arabidopsis seed-specific genes, AtS1 and AtS3. The 5' regulatory regions, or parts thereof, when operably linked to either the coding sequence of a heterologous gene or a sequence complementary to a native plant gene, direct expression of the coding sequence or complementary sequence in a plant seed. The regulatory regions are useful in expression cassettes and expression vectors for the transformation of plants. Also provided are methods of modulating the levels of a heterologous gene such as a fatty acid synthesis or lipid metabolism gene by transforming a plant with the subject expression cassettes and expression vectors.Type: GrantFiled: October 22, 1997Date of Patent: August 8, 2000Assignee: Rhone-Poulenc AgrochimieInventors: Terry L. Thomas, Michael Nuccio
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Patent number: 5977436Abstract: The present invention is directed to 5' regulatory regions of an Arabidopsis oleosin gene. The 5' regulatory regions, when operably linked to either the coding sequence of a heterologous gene or a sequence complementary to a native plant gene, direct expression of the coding sequence or complementary sequence in a plant seed. The regulatory regions are useful in expression cassettes and expression vectors for the transformation of plants. Also provided are methods of modulating the levels of a heterologous gene such as a fatty acid synthesis or lipid metabolism gene by transforming a plant with the subject expression cassettes and expression vectors.Type: GrantFiled: April 9, 1997Date of Patent: November 2, 1999Assignee: Rhone Poulenc AgrochimieInventors: Terry L. Thomas, Zhongsen Li
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Patent number: 5959175Abstract: The present invention is directed to 5' regulatory regions of a sunflower albumin gene. The 5' regulatory regions, when operably linked to either the coding sequence of a heterologous gene or a sequence complementary to a native plant gene direct expression of the coding sequence or complementary sequence in a plant seed. The regulatory regions are useful in expression cassettes and expression vectors for the transformation of plants.Also provided are methods of modulating the levels of a heterologous gene or native plant gene such as a fatty acid synthesis or lipid metabolism gene by transforming a plant with the subject expression cassettes and expression vectors.Type: GrantFiled: April 9, 1997Date of Patent: September 28, 1999Inventors: Terry L. Thomas, Andrew N. Nunberg, Phillip D. Beremand
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Patent number: 5789220Abstract: Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to isolated nucleic acids comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: January 28, 1997Date of Patent: August 4, 1998Assignee: Rhone-Poulenc AgrochimieInventors: Terry L. Thomas, Avutu S. Reddy, Michael Nuccio, Andrew N. Nunberg, Georges L. Freyssinet
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Patent number: 5689050Abstract: Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to an isolated nucleic acid comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: June 7, 1995Date of Patent: November 18, 1997Assignee: Rhone-Poulenc AgrochimieInventors: Terry L. Thomas, Avutu S. Reddy, Michael Nuccio, Georges L. Freyssinet
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Patent number: 5663068Abstract: Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to an isolated nucleic acid comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: June 7, 1995Date of Patent: September 2, 1997Assignee: Rhone Poulenc AgrochimieInventors: Terry L. Thomas, Avutu S. Reddy, Michael Nuccio, Georges L. Freyssinet
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Patent number: 5614393Abstract: Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to isolated nucleic acids comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: December 30, 1994Date of Patent: March 25, 1997Assignee: Rhone-Poulenc AgrochimieInventors: Terry L. Thomas, Avutu S. Reddy, Michael Nuccio, Andrew N. Nunberg, Georges L. Freyssinet
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Patent number: 5552306Abstract: Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to an isolated nucleic acid comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.Type: GrantFiled: September 14, 1994Date of Patent: September 3, 1996Assignee: Rhone-Poulenc AgrochimieInventors: Terry L. Thomas, Avutu S. Reddy, Michael Nuccio, Georges L. Freyssinet