Patents by Inventor Teruaki Yuzuriha

Teruaki Yuzuriha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue plasminogen activator analogs having modified growth factor domains
    Patent number: 5486471
    Abstract: Tissue plasminogen activator analogs containing the growth factor domain of native t-PA, the domain having at least one cysteine residue replaced with another amino acid. The t-PA analogs may further contain a variety of substitutions and/or modifications. Pharmaceutical compositions containing one or more of the t-PA analogs along With a physiologically acceptable carrier or diluent are also disclosed.
    Type: Grant
    Filed: March 6, 1995
    Date of Patent: January 23, 1996
    Assignee: ZymoGenetics, Inc.
    Inventors: Eileen R. Mulvihill, Shinji Yoshitake, Yasunori Ikeda, Suguru Suzuki, Akira Hashimoto, Teruaki Yuzuriha, Bjorn A. Nexo
  • Modified t-PA with kringle-/replaced by another kringle
    Patent number: 5149533
    Abstract: Tissue plasminogen activator analogs exhibiting greater specificity for fibrin than native t-PA are disclosed. The analogs include the K1 domain of native t-PA replaced with another kringle domain mediating the binding of the analog to fibrin. The kringle contains six cysteine residues. The t-PA analogs may further include a variety of substitutions and modifications. Pharmaceutical compositions containing one or more of the t-PA analogs along with a physiologically acceptable carrier or diluent are also disclosed.
    Type: Grant
    Filed: August 12, 1991
    Date of Patent: September 22, 1992
    Assignee: ZymoGenetics, Inc.
    Inventors: Eileen R. Mulvihill, Shinji Yoshitake, Yasunori Ikeda, Suguru Suzuki, Akira Hashimoto, Teruaki Yuzuriha, Bjorn A. Nexo
  • Coated ubidecarenone-containing liposome
    Patent number: 4636381
    Abstract: A coated ubidecarenone-containing liposome which comprises the ubidecarenone-containing liposome and a polysaccharide fatty acid ester applied on the surface of the membrane of said liposome, whereby the ubidecarenone can be selectively transferred in high concentrations to the lungs, spleen and kidneys.
    Type: Grant
    Filed: May 19, 1983
    Date of Patent: January 13, 1987
    Assignee: Eisai Co., Ltd.
    Inventors: Masahiro Takada, Teruaki Yuzuriha, Kouichi Katayama, Junzo Sunamoto