Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Abstract: The present invention aims to provide a new method for producing an indole compound or a salt thereof, which has an ITK inhibitory action, and is useful for the prophylaxis or treatment of inflammatory disease.

Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Abstract: The present invention aims to provide a new method for producing an indole compound or a salt thereof, which has an ITK inhibitory action, and is useful for the prophylaxis or treatment of inflammatory disease.

Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Abstract: Providing an overturn preventing device which can easily be mounted between a top surface of a piece of furniture and a ceiling while an axis line of a damper relative to a vertical direction is inclined at an angle ranging from 15° to 25°. The overturn preventing device includes a damper, a first base portion and a second base portion. The first base portion has a first abutting surface and a first connection. The first base portion is mounted on the top surface of the furniture. The second base portion has a second abutting surface and a second connection. The second base portion is mounted on the ceiling. A relation, X+L sin 15°?Y?X+L sin 25°, is obtained where reference symbol X designates a distance from the first abutting surface to the first connection, reference symbol L designates a length of the damper and reference symbol Y designates a distance from the second abutting surface the second connection.

Abstract: Providing an overturn preventing device which can successfully prevent overturn of an article. The overturn preventing device includes a damper mounted between a piece of furniture and a ceiling and a setting member connected to both ends of the damper. The setting member has a first setting part body and a second setting part body. The first and second setting part bodies and of the setting member are spread when the overturn preventing device is mounted between the furniture and the ceiling. The setting member assumes such a shape as to extend in one direction when the first and second setting part bodies and are unspread.

Abstract: Providing a vibration damping shelf which can suppress fall of articles placed on a shelf member while suppressing shake of other articles or the like. The vibration damping shelf includes a damper and shelf plates. The damper has two ends mounted, on a top surface of a piece of furniture and a ceiling spaced from each other in an up-down direction. The shelf plates are held on the damper.

Abstract: Providing an overturn preventing device which can easily be mounted and can prevent articles from overturn. The overturn preventing device includes an abutting part and a connecting part. The abutting part abuts against a ceiling. The abutting part is disposed so as to extend in one direction while gradually departing from the ceiling. The connecting part has two ends one of which is connected to an end of the abutting part away from the ceiling and the other of which is disposed on a top surface of a piece of furniture. The abutting part is elastically deformed with tilt of the furniture, so that an area of a part of the abutting part abutting against the ceiling is increased.

Abstract: Providing an overturn preventing device which is easy in handling such as carrying. The overturn preventing device includes a damper, a first base portion, a second base portion and a connecting tool. The damper is mounted between a top surface of furniture and a ceiling. An expansion force of compressed gas filling a cylinder is applied to the damper in a direction such that a length of the damper is increased. The first base portion is rotatably connected to one of two ends of the damper and has a first abutting surface which abuts against the top surface of the furniture. The second base portion is rotatably connected to the other end of the damper and has a second abutting surface which abuts against the ceiling. The connecting tool maintains a folded state in which the damper is contracted so that the first base portion and the second base portion come close to each other.

Abstract: The invention provides a compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification. The invention also provides a method for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like in a mammal by administering the compound or pharmaceutically acceptable salt thereof or solvate thereof to the mammal.

Abstract: The present invention aims to provide a new method for producing an indole compound or a salt thereof, which has an ITK inhibitory action, and is useful for the prophylaxis or treatment of inflammatory disease.

Abstract: Providing an overturn preventing device which can be mounted to an article such as furniture irrespective of an installation location of the article and which can prevent the article from being overturned by quakes of an earthquake or the like. The overturn preventing device includes a plurality of dampers mounted between a top surface of the furniture installed on a floor surface and a ceiling. The dampers are compression damper that has a smaller damping force generated during an extending operation than a damping force generated during a compressing operation. The dampers have respective axis lines extending from a ceiling side to the top surface side of the furniture, and the axis lines are downwardly inclined and extend in a plurality of directions in a planar view as viewed from above when the dampers are mounted between the top surface of the furniture and the ceiling.

Abstract: Providing an overturn preventing device which can easily be mounted between a top surface of a piece of furniture and a ceiling while an axis line of a damper relative to a vertical direction is inclined at an angle ranging from 15° to 25°. The overturn preventing device includes a damper, a first base portion and a second base portion. The first base portion has a first abutting surface and a first connection. The first base portion is mounted on the top surface of the furniture. The second base portion has a second abutting surface and a second connection. The second base portion is mounted on the ceiling. A relation, X+L sin 15°?Y?X+L sin 25°, is obtained where reference symbol X designates a distance from the first abutting surface to the first connection, reference symbol L designates a length of the damper and reference symbol Y designates a distance from the second abutting surface the second connection.

Abstract: Providing an overturn preventing device which can successfully prevent overturn of an article. The overturn preventing device includes a damper mounted between a piece of furniture and a ceiling and a setting member connected to both ends of the damper. The setting member has a first setting part body and a second setting part body. The first and second setting part bodies and of the setting member are spread when the overturn preventing device is mounted between the furniture and the ceiling. The setting member assumes such a shape as to extend in one direction when the first and second setting part bodies and are unspread.

Abstract: A method for the prevention of diseases caused by thrombus or embolus. The method is to separately administer 2-acetoxy-5-(?-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine or a pharmaceutically acceptable salt thereof, and aspirin, in their pharmacologically effective amounts, to a warm-blooded animal.

Abstract: A combination of 2-acetoxy-5-(?-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine or a pharmaceutically acceptable salt thereof, and aspirin, which possess excellent inhibitory activity against platelet aggregation and thrombogenesis, and is useful for preventing or treating diseases caused by thrombus or embolus.

Abstract: A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.

Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.