Patents by Inventor Teruhisa Kawamura

Teruhisa Kawamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20220315901
    Abstract: The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency.
    Type: Application
    Filed: December 8, 2020
    Publication date: October 6, 2022
    Applicant: SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: RONALD EVANS, MICHAEL DOWNES, YASUYUKI KIDA, TERUHISA KAWAMURA, ZONG WEI, RUTH T. YU, ANNETTE R. ATKINS
  • Reprogramming progenitor compositions and methods of use therefore
    Patent number: 10920199
    Abstract: The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency. In particular embodiments the invention is predicated upon increased expression of an estrogen related receptor and changes in the oxidative and glycolytic pathways.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: February 16, 2021
    Assignee: SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: Ronald Evans, Michael Downes, Yasuyuki Kida, Teruhisa Kawamura, Zong Wei, Ruth T. Yu, Annette R. Atkins
  • REPROGRAMMING PROGENITOR COMPOSITIONS AND METHODS OF USE THEREFORE
    Publication number: 20180044642
    Abstract: The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency. In particular embodiments the invention is predicated upon increased expression of an estrogen related receptor and changes in the oxidative and glycolytic pathways.
    Type: Application
    Filed: February 26, 2016
    Publication date: February 15, 2018
    Applicant: Salk Institute for Biological Studies
    Inventors: Ronald EVANS, Michael DOWNES, Yasuyuki KIDA, Teruhisa KAWAMURA, Zong WEI, Ruth T. YU, Annette R. ATKINS
  • METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS, CARDIOMYOCYTES OR PRECURSOR CELLS THEREOF
    Publication number: 20150337266
    Abstract: Nuclear reprogramming substances are contacted with a somatic cell and, after culture, cell population is fractionated based on the expression of Sca-1 or EpCam and CD34. By sorting Sca-1-negative CD34-negative cells or EpCam-positive CD34-negative cells, a cell population having high possibility of iPS cell formation can be selected. On the other hand, Sca-1-positive CD34-positive cells or EpCam-negative CD34-positive cells are useful as a source of myocardial cell or a progenitor cell thereof having a low risk of tumor formation.
    Type: Application
    Filed: December 27, 2013
    Publication date: November 26, 2015
    Inventor: Teruhisa KAWAMURA
  • INDUCED PLURIPOTENT STEM CELL GENERATION USING TWO FACTORS AND P53 INACTIVATION
    Publication number: 20120076762
    Abstract: Methods and compositions are provided for, inter alia, the generation of induced pluripotent stem cells. Induced pluripotent stem cells may be generated by reprogramming and inhibition of p53. Further, useful intermediates for the generation of induced pluripotent stem cells are also provided.
    Type: Application
    Filed: March 24, 2010
    Publication date: March 29, 2012
    Applicant: THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: Teruhisa Kawamura, Jotaro Suzuki, Yunyuan V. Wang, Angel Raya, Geoffrey M. Wahl, Juan Carlos Izpisua Belmonte