Patents by Inventor Terukage Hirata

Terukage Hirata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel propenohydroxamic acid derivatives
    Publication number: 20040029928
    Abstract: Provided are a propenohydroxamic acid derivative represented by the following formula (1): 1
    Type: Application
    Filed: February 26, 2003
    Publication date: February 12, 2004
    Inventors: Terukage Hirata, Keiji Misumi, Kenji Ito, Kenichi Inokuma, Kimiko Katayama
  • Process for producing N-biphenylmethylthiadiazoline derivative or salt thereof and intermediate for producing the same
    Patent number: 5965738
    Abstract: Described is a process for producing an N-biphenyl-methylthiadiazoline derivative (7) in accordance with the reaction formula described below. According to the process of the present invention, it is possible to produce a compound (7) advantageously from the industrial viewpoint.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: October 12, 1999
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Satoshi Inoue, Nobuya Sakae, Masaharu Yokomoto, Kouji Nishimura, Terukage Hirata
  • Process for producing tetrazolylated biphenylmethane derivatives
    Patent number: 5912353
    Abstract: The present invention relates to a process for producing a tetrazolylated biphenylmethane derivatives (6) or salts thereof in accordance with the below-described reaction scheme wherein R.sup.1 represents an alkyl; R.sup.2 represents H, etc.; Z represents a halogen, etc.; and A represents a cycloalkene, etc. According to the above process, a tetrazolylated biphenylmethane derivative can be industrially and advantageously produced with short steps.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: June 15, 1999
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Satoshi Inoue, Kouji Nishimura, Masaharu Yokomoto, Nobuya Sakae, Terukage Hirata
  • Biphenylmethane derivatives and pharmaceuticals containing the same
    Patent number: 5654322
    Abstract: This invention relates to a biphenylmethane derivative represented by the formula (1): ##STR1## wherein A represents a group ##STR2## in which R.sup.1, X, Y, Z and B are as defined in the Specification. The compounds have potent angiotensin II antagonist activity and anti-hypertensive effect. They have therapeutic utility for circulatory diseases such as hypertension, heart diseases and cerebral apoplexy.
    Type: Grant
    Filed: February 10, 1995
    Date of Patent: August 5, 1997
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Terukage Hirata, Nobuya Sakae, Koichi Tamura, Masayasu Okuhira, Hirotaka Amano, Masaharu Yokomoto, Jun Nomiyama
  • Dihydropyridine derivative
    Patent number: 5260444
    Abstract: The present invention provides dihydropyridine derivatives represented by the following formula (I) ##STR1## and salts thereof. They have extremely strong, slow and long-acting vasodilating action and antihypertensive action with less adverse effects so that they are useful as therapeutic agents for cardiovascular diseases.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: November 9, 1993
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Terukage Hirata, Yasushi Yoshimura, Masanori Kakimoto, Koichi Tamura, Harunobu Amagase
  • Dihydropyridine derivative
    Patent number: 5208245
    Abstract: The present invention provides dihydropyridine derivatives represented by the following formula (I) ##STR1## and salts thereof. They have extremely strong, slow and long-acting vasodilating action and antihypertensive action with less adverse effects so that they are useful as therapeutic agents for cardiovascular diseases.
    Type: Grant
    Filed: May 7, 1991
    Date of Patent: May 4, 1993
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Terukage Hirata, Yasushi Yoshimura, Masanori Kakimoto, Koichi Tamura, Harunobu Amagase
  • Method for improving cerebral circulation
    Patent number: 4816481
    Abstract: Disclosed herein is a cerebral-circulation-metabolism-function-improving agent which contains a 2,6-diphenyl-3,7-dioxabicyclo[3.3.0]octane derivative represented by the following formula as the effective ingredient: ##STR1## wherein, each of R.sub.1, R.sub.3, R.sub.4 and R.sub.6 represents a hydrogen atom or a lower alkoxyl group; each of R.sub.2 and R.sub.5 represents a hydrogen atom, a .beta.-D-glucosyl group or a hydroxyl group; and each of R.sub.7 and R.sub.8 represents an oxygen atom or two hydrogen atoms.
    Type: Grant
    Filed: July 21, 1987
    Date of Patent: March 28, 1989
    Assignee: Wakunaga Seiyaku Kabushiki Kaisha
    Inventors: Naoyuki Takasugi, Mitsuyasu Ushijima, Satoshi Inoue, Terukage Hirata