Patents by Inventor Teruto Hashiguchi

Teruto Hashiguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same
    Patent number: 10627412
    Abstract: The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.
    Type: Grant
    Filed: March 17, 2011
    Date of Patent: April 21, 2020
    Assignee: KAGOSHIMA UNIVERSITY
    Inventors: Ikuro Maruyama, Teruto Hashiguchi, Salunya Tancharoen, Ko-ichi Kawahara, Kenji Tanaka, Lyang-ja Lee
  • Method for inspecting gastroenterological cancer by utilizing N-linked sugar chain
    Patent number: 8932866
    Abstract: As a result of collecting blood from pancreatic cancer patients, esophageal cancer patients, and stomach cancer patients, and conducting mass spectrometry on N-linked sugar chains in the plasmas, sugar chains whose abundances are significantly different from those of healthy subjects have been successfully identified from the blood samples of the cancer patients.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: January 13, 2015
    Assignees: Kagoshima University, Sumitomo Bakelite Co., Ltd.
    Inventors: Shoji Natsugoe, Yasuto Uchikado, Teruto Hashiguchi, Hiroyuki Shinchi, Kosei Maemura, Yuko Mataki, Norichika Moriwaki, Masaru Sekijima, Hideyuki Shimaoka, Midori Abe, Masao Fukushima, Kota Igarashi, Hiroki Abe, Taichi Aihara
  • DIAGNOSTIC MARKER FOR DIGESTIVE ORGAN CANCER AND INSPECTION METHOD FOR DIGESTIVE ORGAN CANCER
    Publication number: 20140273049
    Abstract: A diagnostic marker for digestive organ cancer according to the present invention is used for determining whether or not to have a digestive organ cancer. The diagnostic marker for digestive organ cancer contains at least one of N-binding type sugar chains released from a glycoprotein contained in blood and represented by the following formulas (1) to (6). This makes it possible to provide a diagnostic marker for digestive organ cancer capable of being used for an inspection method of easily determining whether or not to have a digestive organ cancer at an early stage, and an inspection method for digestive organ cancer of easily determining whether or not to have a digestive organ cancer at an early stage.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 18, 2014
    Applicants: Kagoshima University, SUMITOMO BAKELITE COMPANY LIMITED
    Inventors: Shoji Natsugoe, Yasuto Uchikado, Teruto Hashiguchi, Hiroyuki Shinchi, Kosei Maemura, Yuko Mataki, Norichika Moriwaki, Masaru Sekijima, Hideyuki Shimaoka, Midori Sakaguchi, Masao Fukushima, Kota Igarashi, Hiroki Abe, Taichi Aihara
  • METHOD FOR INSPECTING GASTROENTEROLOGICAL CANCER BY UTILIZING N-LINKED SUGAR CHAIN
    Publication number: 20130109043
    Abstract: As a result of collecting blood from pancreatic cancer patients, esophageal cancer patients, and stomach cancer patients, and conducting mass spectrometry on N-linked sugar chains in the plasmas, sugar chains whose abundances are significantly different from those of healthy subjects have been successfully identified from the blood samples of the cancer patients.
    Type: Application
    Filed: April 6, 2011
    Publication date: May 2, 2013
    Applicants: KAGOSHIMA UNIVERSITY, MITSUBISHI CHEMICAL MEDIENCE CORPORATION, SUMITOMO BAKELITE CO., LTD.
    Inventors: Shoji Natsugoe, Yasuto Uchikado, Teruto Hashiguchi, Hiroyuki Shinchi, Kosei Maemura, Yuko Mataki, Norichika Moriwaki, Masaru Sekijima, Hideyuki Shimaoka, Midori Abe, Masao Fukushima, Kota Igarashi, Hiroki Abe, Taichi Aihara
  • PERIODONTAL-DISEASE-SPECIFIC PEPTIDE, AND TREATMENT AND DIAGNOSIS OF PERIODONTAL DISEASE USING SAME
    Publication number: 20130086703
    Abstract: The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.
    Type: Application
    Filed: March 17, 2011
    Publication date: April 4, 2013
    Inventors: Ikuro Maruyama, Teruto Hashiguchi, Salunya Tancharoen, Ko-ichi Kawahara, Kenji Tanaka, Lyang-Ja Lee