Abstract: A surface wipe for real time detection of trace amounts of toxic substances on surfaces. The wipe includes a collection surface that is swiped across a surface to be tested. The collection media filters dirt and other materials to prevent or reduce inaccurage readings caused by dirt or other foreign matter. A reactive media next to the collecting surface is impregnated with chemicals that react to the toxic substances to create a color change in the reactive media. The color change may be viewed through a clear backing.