Patents by Inventor Teshome T Mebatsion

Teshome T Mebatsion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable, attenuated rabies virus mutants and live vaccines thereof
    Patent number: 6719981
    Abstract: The present invention relates to recombinant rabies virus mutants comprising a mutation in the viral genome, whereby said mutation comprises at least a substitution of the Arg333 codon in the gene encoding the G protein with a codon that differs by three nucleotides from said Arg333 codon. These rabies virus mutants have a glycoprotein G that comprises an amino acid at position 333 which is encoded by a codon that differs by all three nucleotides from the Arg codon in amino acid position 333 in the glycoprotein of the parental virus. Said recombinant rabies virus mutants are stable and non-pathogenic in immune competent animals and are suitable for use in a live, attenuated anti-rabis vaccine.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: April 13, 2004
    Assignee: Akzo Nobel N.V.
    Inventors: Teshome T Mebatsion, Karl Klaus Conzelmann