Patents by Inventor Tessa LUEHMANN

Tessa LUEHMANN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminomethyl-functionalized denatonium derivatives, their preparation and use
    Patent number: 11891352
    Abstract: The present invention is directed to compounds of the general formula (I) and salts thereof wherein X? is halide, pseudohalide, sulphate, benzoate, acetate, trifluoroacetate, hydroxide, saccharinate or capsaicinate; R10 is hydrogen or C1-C10-alkyl; and R1-R9 independently are hydrogen, halogen, C1-C5-alkyl, C1-C4-alkoxy, C1-C20-alkoxycarbonyl. The invention is furthermore directed to a method for the preparation of these compounds. The compounds can be used as bitter substances in medicine, pharmaceutics and/or diagnostics. They can furthermore be used for the coupling to proteins and peptides by means of forming a peptide bond between the amino-group of the compounds of the present invention and a carboxyl-group of the protein or peptide.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: February 6, 2024
    Assignee: Julius-Maximilians-Universitaet
    Inventors: Lorenz Meinel, Tessa Luehmann, Martina Raschig
  • COMPOUNDS AND METHODS FOR THE IMMOBILIZATION OF MYOSTATIN-INHIBITORS ON THE EXTRACELLULAR MATRIX BY TRANSGLUTAMINASE
    Publication number: 20210138043
    Abstract: The present invention relates to compounds and their use in the treatment of lesions, in tissue regeneration and/or tissue engineering. The compounds act as substrates for enzymes having transglutaminase activity and are suitable for their immobilization and/or attached therapeutic or diagnostic molecules on extracellular matrix (ECM) or synthetic ECM-derived materials, in particular for the immobilization of myostatin inhibitors.
    Type: Application
    Filed: May 17, 2019
    Publication date: May 13, 2021
    Inventors: LORENZ MEINEL, TESSA LÜHMANN, ALEXANDRA BRAUN
  • AMINOMETHYL-FUNCTIONALIZED DENATONIUM DERIVATIVES, THEIR PREPARATION AND USE
    Publication number: 20210087138
    Abstract: The present invention is directed to compounds of the general formula (I) and salts thereof wherein X? is halide, pseudohalide, sulphate, benzoate, acetate, trifluoroacetate, hydroxide, saccharinate or capsaicinate; R10 is hydrogen or C1-C10-alkyl; and R1-R9 independently are hydrogen, halogen, C1-C5-alkyl, C1-C4-alkoxy, C1-C20-alkoxycarbonyl. The invention is furthermore directed to a method for the preparation of these compounds. The compounds can be used as bitter substances in medicine, pharmaceutics and/or diagnostics. They can furthermore be used for the coupling to proteins and peptides by means of forming a peptide bond between the amino-group of the compounds of the present invention and a carboxyl-group of the protein or peptide.
    Type: Application
    Filed: February 20, 2019
    Publication date: March 25, 2021
    Applicant: Julius-Maximilians-Universitaet Wuerzburg
    Inventors: Lorenz MEINEL, Tessa LUEHMANN, Martina RASCHIG
  • PHARMACEUTICALS AND DEVICES FOR THE COVALENT IMMOBILIZATION TO THE EXTRACELLULAR MATRIX BY TRANSGLUTAMINASE
    Publication number: 20200283494
    Abstract: The present invention relates to compounds and their use in the treatment of lesions, in tissue regeneration and/or tissue engineering. The compounds act as substrates for enzymes having transglutaminase activity and are suitable for their immobilization on extracellular substrates or matrices.
    Type: Application
    Filed: August 7, 2018
    Publication date: September 10, 2020
    Inventors: Alexandra BRAUN, Lorenz MEINEL, Tessa LÜHMANN