Abstract: Methods and compositions using an inhibitor of EGFR signaling for prevention or an inhibitor of EGFR signaling and a nucleic acid molecule encoding an atonal-associated factor for treatment of hearing loss are described.

Abstract: Methods and compositions using an inhibitor of EGFR signaling for prevention or an inhibitor of EGFR signaling and a nucleic acid molecule encoding an atonal-associated factor for treatment of hearing loss are described.

Abstract: A power conversion system includes a housing (outer housing) and a power converter. The power converter is arranged in an internal space of the housing. An outer peripheral surface of the housing is provided with an air inlet and an air outlet. The air outlet communicates with the air inlet via the internal space of the housing and is located below the air inlet.

Abstract: Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described.

Abstract: Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described.

Abstract: A power conversion system includes a housing (outer housing) and a power converter. The power converter is arranged in an internal space of the housing. An outer peripheral surface of the housing is provided with an air inlet and an air outlet. The air outlet communicates with the air inlet via the internal space of the housing and is located below the air inlet.

Abstract: Methods and compositions using an inhibitor of EGFR signaling for prevention or an inhibitor of EGFR signaling and a nucleic acid molecule encoding an atonal-associated factor for treatment of hearing loss are described.

Abstract: Methods and compositions using a nucleic acid molecule encoding an atonal-associated factor in combination with a co-transcription factor and/or inhibitor of a gene silencing complex to change the sensory perception of an animal are described.

Abstract: The present invention is objected to polish the surface of the object material with a high quality at a high polishing rate. The object surface is polished using a wet polishing method. Slurry is produced by scattering abrasive particles into pure water. In the abrasive particle, where components which has a mechanochemical effect and which reacts to the friction heat generated in polishing the object material are joined with each other and integrated to a particle. There, respective component is joined with each other using a mechanical alloying process, while maintaining the inherent material properties. When the slurry is used in a lapping process of sapphire, silicon carbide, gallium nitride and the like, the polishing process can be substantially shortened and the processing cost is drastically reduced. Further, it secures a high quality of the polishing surface. The abrasive particle can be used repeatedly in the polishing process.

Abstract: [Object] The present invention is objected to polish the surface of the object material with a high quality at a high polishing rate. [Solution] The object surface is polished using a wet polishing method. Slurry is produced by scattering abrasive particles into pure water. In the abrasive particle, where components which has a mechanochemical effect and which reacts to the friction heat generated in polishing the object material are joined with each other and integrated to a particle. There, respective component is joined with each other using a mechanical alloying process, while maintaining the inherent material properties. When the slurry is used in a lapping process of sapphire, silicon carbide, gallium nitride and the like, the polishing process can be substantially shortened and the processing cost is drastically reduced. Further, it secures a high quality of the polishing surface. The abrasive particle can be used repeatedly in the polishing process.

Abstract: In a switching power supply device which intermittently executes a switching operation, a power loss which occurs in resumption of the switching operation is reduced. A semiconductor device works as a control circuit for the switching power supply device, and includes: an intermittent oscillation control circuit which alternately gives an instruction for execution and suspension of the switching operation of a switching element; a bottom detecting circuit which detects a bottom of a ringing voltage that develops when the switching element is OFF; a bottom-monitoring time period timing circuit which times a bottom-monitoring time period starting as soon as the instruction for the execution of the switching operation is given; and a turn-on control circuit which turns ON, before the timing of the bottom-monitoring time period ends, the switching element only when the bottom of the ringing voltage is detected.

Abstract: In a switching power supply device which intermittently executes a switching operation, a power loss which occurs in resumption of the switching operation is reduced. A semiconductor device works as a control circuit for the switching power supply device, and includes: an intermittent oscillation control circuit which alternately gives an instruction for execution and suspension of the switching operation of a switching element; a bottom detecting circuit which detects a bottom of a ringing voltage that develops when the switching element is OFF; a bottom-monitoring time period timing circuit which times a bottom-monitoring time period starting as soon as the instruction for the execution of the switching operation is given; and a turn-on control circuit which turns ON, before the timing of the bottom-monitoring time period ends, the switching element only when the bottom of the ringing voltage is detected.

Abstract: A semiconductor device providing a control circuit for controlling a switching power supply apparatus includes: an intermittent-oscillation control circuit which outputs an enable signal providing instructions to execute and suspend switching alternately; a turn-on control circuit which changes between an execution state and a suspension state of the switching according to the enable signal, and outputs, only in the execution state, a turn-on signal which turns on the switching element with a switching period; and an intermittent-oscillation frequency control circuit which causes the turn-on control circuit to delay the changing between the execution state and the suspension state so that an intermittence period including periods during which the turn-on control circuit is in the execution state and the turn-on control circuit is in the suspension state falls outside of a specific time range. Intermittent oscillation is thus operated out of a specific frequency band within an audible frequency range.

Abstract: The present invention includes a voltage clamping circuit 6 for outputting a voltage signal, which has been clamped to a predetermined voltage, from the drain voltage of a switching element 1, and a turn-on detection circuit 7 for detecting the turn-on timing of the switching element 1 from the voltage signal. Thus it is possible to turn on the switching element 1 at the minimum value of the drain voltage without adding external terminals.

Abstract: A semiconductor device providing a control circuit for controlling a switching power supply apparatus includes: an intermittent-oscillation control circuit which outputs an enable signal providing instructions to execute and suspend switching alternately; a turn-on control circuit which changes between an execution state and a suspension state of the switching according to the enable signal, and outputs, only in the execution state, a turn-on signal which turns on the switching element with a switching period; and an intermittent-oscillation frequency control circuit which causes the turn-on control circuit to delay the changing between the execution state and the suspension state so that an intermittence period including periods during which the turn-on control circuit is in the execution state and the turn-on control circuit is in the suspension state falls outside of a specific time range. Intermittent oscillation is thus operated out of a specific frequency band within an audible frequency range.

Abstract: A plurality of arrangements for detecting an overload of energy supplied to an output part enables selecting latch-off or auto-recovery overload protection by the operation of a switching device. When the drain current peak of the switching device exceeds a predetermined level denoting an overload, the FB pin voltage also rises to latch off, and when the drain current peak then reaches a maximum level, the CC pin voltage drops to a predetermined level and limits the oscillation period of the switching device because output power cannot be increased even if the load increases further. Latch-off overload protection can be applied when the drain current peak exceeding a predetermined level is detected, and auto-recovery overload protection can be applied when the CC pin voltage is detected to drop to a predetermined level.

Abstract: The present invention includes a turn-off signal modulating circuit that periodically varies a turn-off timing of a switching element 2 at a preset modulation time after a current detection by a drain current detecting circuit 15, and by modulating the peak of a current flowing through the switching element 2, diffuses switching noise while preventing concentration of an oscillating frequency at a constant frequency even under a constant input voltage and a constant load.

Abstract: A high-breakdown voltage semiconductor switching device includes a resurf region of a second conductivity type; a base region of a first conductivity type formed to be adjacent to the resurf region; an emitter/source region of the second conductivity type formed in the base region to be spaced from the resurf region; a gate electrode formed to cover a portion of the emitter/source region and a portion of the resurf region; a drain region of the second conductivity type formed in the resurf region to be spaced from the base region; and a collector region of the first conductivity type formed in the resurf region to be spaced from the base region. Furthermore, it includes an electrode connected to the collector region and the drain region and an electrode connected to the base region and the emitter/source region.

Abstract: The present invention includes a voltage clamping circuit 6 for outputting a voltage signal, which has been clamped to a predetermined voltage, from the drain voltage of a switching element 1, and a turn-on detection circuit 7 for detecting the turn-on timing of the switching element 1 from the voltage signal. Thus it is possible to turn on the switching element 1 at the minimum value of the drain voltage without adding external terminals.

Abstract: A CMP conditioner having excellent corrosion resistance around abrasive grains includes a grindstone base having, formed on one side, an abrasive grain layer including abrasive grains fixed in a metallic bonding phase treated to form a first protective layer comprising an oxide on the surface of the metallic bonding phase of the abrasive grain layer by the sol-gel method. Subsequently, an aerosol obtained by dispersing fine particles of a brittle material in a gas is jetted and caused to strike on the surface of the first protective layer to form a second protective layer comprising a thick oxide film.