Abstract: The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)n motif-REP]m or Formula 2: [(A)n motif-REP]m-(A)n motif, and having a serine residue content rate of less than 5.5%. [In Formula 1 and Formula 2, the (A)n motif represents an amino acid sequence consisting of 4 to 27 amino acid residues, and the number of alanine residues with respect to the total number of amino acid residues in the (A)n motif is 80% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300. The plurality of (A)n motifs may be the same amino acid sequence or different amino acid sequences. A plurality of REPs may be the same amino acid sequence or different amino acid sequences.

Abstract: A production method of a protein composition, the method comprising a step of hydrolyzing an ester group by bringing a raw material composition containing an esterified protein into contact with an acidic or basic medium.

Abstract: A spinning solution composition which provides regenerated silk fiber that exhibits a strength and elongation close to those of natural silk fiber, is rapidly degradable in vivo, and can be caused to have ability to gradually release a drug to prevent inflammation; a process for producing such regenerated silk fiber by use of the composition; and regenerated silk fiber obtained through the process.

Abstract: A spinning solution composition which provides regenerated silk fiber that exhibits a strength and elongation close to those of natural silk fiber, is rapidly degradable in vivo, and can be caused to have ability to gradually release a drug to prevent inflammation; a process for producing such regenerated silk fiber by use of the composition; and regenerated silk fiber obtained through the process.

Abstract: The present invention discloses a sample tube for the magic angle high-speed rotation method used in a solid nuclear magnetic resonance device probe wherein a radio wave irradiation/detection coil is disposed close to a sample and a method of measuring a high resolution nuclear magnetic resonance absorption spectrum using the same. This tube is suitable for solid nuclear magnetic resonance (solid NMR) measurements of minute amounts of sample. The sample tube has a capillary part filled with a sample and non-capillary parts situated at its two ends, and a spinner which can be detachably inserted into at least one of the outer ends of the non-capillary parts. The capillary part and non-capillary parts are made of a ceramic and/or polymer material.

Abstract: The present invention discloses a sample tube for the magic angle high-speed rotation method used in a solid nuclear magnetic resonance device probe wherein a radio wave irradiation/detection coil is disposed close to a sample and a method of measuring a high resolution nuclear magnetic resonance absorption spectrum using the same. This tube is suitable for solid nuclear magnetic resonance (solid NMR) measurements of minute amounts of sample. The sample tube has a capillary part filled with a sample and non-capillary parts situated at its two ends, and a spinner which can be detachably inserted into at least one of the outer ends of the non-capillary parts. The capillary part and non-capillary parts are made of a ceramic and/or polymer material.

Abstract: A method of producing silk or silk-like protein wherein silk or a silk-like polymer comprising at least one protein selected from among domestic silkworm fibroin, wild silkworm fibroin, elastin and fibronectin, and essentially comprising the aforesaid domesticated silkworm fibroin or silkworm fibroin is designed. The minimum unit of the silk or the thus designed polymer is synthesized, and the polymer of the minimum unit thus synthesized is integrated into at least one expression vector selected from among expression vectors containing T7 promoter. Then, the expression vector is integrated into E. coli BL21 (DE3) pLysS or BLR(DE3) pLysS, and the E. coli is grown in a medium selected from among composite media.

Abstract: A nonwoven fabric comprising silk fibroin and/or very fine fibers of a silk-material, and a method of preparing a nonwoven fabric comprising silk or a silk-like material wherein said silk fibroin and/or silk-like material is dissolved in hexafluoroacetone hydrate or a solvent having this as its main component, and then performing electrospinning.

Abstract: A silk-like material precursor, a method of producing such a precursor and a silk-like material produced from such a precursor are provided.

Abstract: A method of manufacturing silk or silk-like fibers materials, wherein a solution wherein silk fibroins and/or silk-like materials are dissolved in hexafluoroacetone hydrate, is spun and extended if necessary, and a method of manufacturing a silk or silk-like film wherein a solution in which silk fibroins and/or silk-like materials are dissolved in hexafluoroacetone hydrate, developed, and extended after drying if necessary.

Abstract: A luminescent probe complex for measuring pH comprising, polypyridine ligands having ion dissociable substituents on their carbon rings and a transition metal ion selected from the elements of the VIII group of the periodic table.Also disclosed is a luminescent probe membrane for measuring pH wherein the probe complex is contained in a macromolecular membrane. Further disclosed is a device for measuring pH wherein the probe membrane is immobilized at the tip of an optical fiber.A method for measuring pH using the above are also disclosed. The present invention enables measurement of pH of microenvironments.