Patents by Inventor Tetsuo Okutsu

Tetsuo Okutsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11643430
    Abstract: There is provided with a porphyrin compound represented by Formula (I) or a salt thereof; where A is a linking group represented as —X—NHCO— where X is a C1 to C6 alkylene group, each of R1, R2, R4, R5, R7, R8, R10, and R11 is a hydrogen atom, each of R3, R6, and R9 is a substituent of Formula; R12 is selected from a group of substituents represented by Formulae, R13 is a sulfo group, Ra, Rb, and Rc are substituents independently selected from C1 to C6 alkyl groups, and Rd is a hydrogen atom or a C1 to C6 alkyl group, and Rx is a substituent represented by General Formula. The porphyrin compound is useful as a cancer therapeutic agent, photosensitizer and fluorescent probe.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: May 9, 2023
    Assignees: M.T.3, INC., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hiroaki Horiuchi, Masahiko Oshige, Ichiro Matsuo, Tetsuo Okutsu, Shinji Katsura, Toshitada Yoshihara, Seiji Tobita, Fumio Sugawara, Kengo Sakaguchi
  • Publication number: 20220178050
    Abstract: Electromagnetic waves are uniformly distributed on the light-receiving surface side by taking advantage of their property of being easily concentrated in sharp parts, and the front area (SA) on the emission surface side is made larger than the back area (SB) on the light-receiving surface side (SA/SB>1), thereby forming a more moderate electric field region. A reduced gold fine particle group (average particle size: 20 nm) was self-assembled on a transparent polyester resin film and half-submerged and fixed. This base material was repeatedly immersed in an electroless gold plating solution so that gold particles were deposited on the gold fine particles. 10 microliters of a protein solution was added dropwise to this nanostructured substrate, and crystallized by a hanging drop vapor diffusion method.
    Type: Application
    Filed: April 1, 2020
    Publication date: June 9, 2022
    Inventors: Tetsuo OKUTSU, Masahiro ITO, Akihiro TAKURA
  • Publication number: 20220064203
    Abstract: There is provided with a compound represented by Formula or a salt thereof; where A is a linking group represented as —X—NHCO— where X is a C1 to C6 alkylene group, each of R1, R2, R4, R5, R7, R8, R10, and R11 is a hydrogen atom, each of R3, R6, and R9 is a substituent of Formula; R12 is selected from a group of substituents represented by Formulae, R13 is a sulfo group, Ra, Rb, and Rc are substituents independently selected from C1 to C6 alkyl groups, and Rd is a hydrogen atom or a C1 to C6 alkyl group, and Rx is a substituent represented by General Formula.
    Type: Application
    Filed: August 31, 2021
    Publication date: March 3, 2022
    Applicants: M.T.3, Inc., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hiroaki HORIUCHI, Masahiko OSHIGE, Ichiro MATSUO, Tetsuo OKUTSU, Shinji KATSURA, Toshitada YOSHIHARA, Seiji TOBITA, Fumio SUGAWARA, Kengo SAKAGUCHI
  • Patent number: 9987610
    Abstract: A crystallization substrate of the present invention includes a noble metal vapor-deposited film having an absorbance in a 500 to 1,000 nm wavelength range and formed in all or part of one surface of the substrate. The noble metal vapor-deposited film has an average thickness of 0.1 to 60 nm. The noble metal vapor-deposited film is a continuous film with a pit formed by vapor deposition in part of the film and surrounded by the continuous film.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: June 5, 2018
    Assignee: National University Corporation Gunma University
    Inventor: Tetsuo Okutsu
  • Publication number: 20150017702
    Abstract: A crystallization substrate of the present invention includes a noble metal vapor-deposited film having an absorbance in a 500 to 1,000 nm wavelength range and formed in all or part of one surface of the substrate. The noble metal vapor-deposited film has an average thickness of 0.1 to 60 nm. The noble metal vapor-deposited film is a continuous film with a pit formed by vapor deposition in part of the film and surrounded by the continuous film.
    Type: Application
    Filed: January 25, 2013
    Publication date: January 15, 2015
    Inventor: Tetsuo Okutsu
  • Publication number: 20120204783
    Abstract: A container for crystallization of a biopolymer of the invention is provided that includes a structure wherein two or more noble metals and/or noble metal-coated bodies are arranged at an interval of 1 to 1,000 nm. There are also provided a crystallization apparatus of a biopolymer, comprising the container for crystallization of a biopolymer, a method for producing a biopolymer crystal, comprising the steps of preparing the container for crystallization of a biopolymer, and making the structure contact with a biopolymer solution, and a substrate for crystallization of a biopolymer, having a structure wherein two or more noble metals and/or noble metal-coated bodies are arranged at an interval of 1 to 1,000 nm.
    Type: Application
    Filed: September 1, 2010
    Publication date: August 16, 2012
    Applicants: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Tetsuo Okutsu, Kosei Ueno, Hiroaki Misawa
  • Patent number: 5496694
    Abstract: A silver halide photographic light-sensitive material includes a support having provided thereon a silver halide emulsion layer containing a silver halide emulsion in which, when that a specific silver iodide content is I mol % (0.3<I<20), silver halide grains having a silver iodide content ranging between 0.7I and 1.3I and containing 10 or more dislocation lines per grain account for 100 to 50% of all grains, and an average aspect ratio of all tabular grains is 8 to 40.
    Type: Grant
    Filed: March 2, 1994
    Date of Patent: March 5, 1996
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Makoto Kikuchi, Tetsuo Okutsu
  • Patent number: 5472837
    Abstract: A silver halide emulsion comprising 50% to 100% of projected area of all silver halide grains are occupied by hexagonal tabular silver halide grains which have an aspect ratio of 8 to 40, which have a ratio of the longest side to the shortest side of 1 to 2, and which have an average silver iodide content of 2 mol % to 10 mol %, and all silver halide grains have a grain size of variation coefficient of 8% to 20%. A method of preparing the emulsion described above, comprising a nucleation step and a grain-growing step and in which a dispersant used in the nucleation step is low-molecular gelatin having a molecular weight of 5,000 to 25,000, and nucleation time t (seconds) in the nucleation step satisfies the relationship of 1<t<-T+90, where T (.degree.C.) is a temperature of a reaction vessel at the time of the nucleation step.
    Type: Grant
    Filed: February 1, 1994
    Date of Patent: December 5, 1995
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Tetsuo Okutsu