Abstract: A data generation device includes: an acquisition part configured to acquire measurement data that corresponds to measurement values, obtained in chronological order, corresponding to a behavior of a key or a member coordinating with the key for each of a plurality of keys; and a data generation part configured to generate display data for displaying a screen showing the measurement values corresponding to each of the plurality of keys along a time axis based on the acquired measurement data.

Abstract: A detection device includes: a movement detector that includes light emitters and light receivers, wherein in accordance with movement of a moving body among moving bodies, each corresponding to a different combination of a light emitter and a light receiver, a light reception level of the light receiver in a combination corresponding to the moving body changes; and a processor coupled to a memory storing instructions that, when executed by the processor, configure the processor to: cause each of the light emitters to sequentially emit light in each light emission period by providing a driving signal, and cause a signal level of the driving signal to differ between unit periods within the light emission period; and select, for each light emission period, a light reception level in one of the unit periods within the light emission period as a detected value for each of the light receivers.

Abstract: A data generation device includes: an acquisition part configured to acquire measurement data that corresponds to measurement values, obtained in chronological order, corresponding to a behavior of a key or a member coordinating with the key for each of a plurality of keys; and a data generation part configured to generate display data for displaying a screen showing the measurement values corresponding to each of the plurality of keys along a time axis based on the acquired measurement data.

Abstract: A detection device includes: a movement detector that includes light emitters and light receivers, wherein in accordance with movement of a moving body among moving bodies, each corresponding to a different combination of a light emitter and a light receiver, a light reception level of the light receiver in a combination corresponding to the moving body changes; and a processor coupled to a memory storing instructions that, when executed by the processor, configure the processor to: cause each of the light emitters to sequentially emit light in each light emission period by providing a driving signal, and cause a signal level of the driving signal to differ between unit periods within the light emission period; and select, for each light emission period, a light reception level in one of the unit periods within the light emission period as a detected value for each of the light receivers.

Abstract: A tau aggregation inhibitor can sufficiently inhibit a tau protein from aggregating in cells. The inhibitor includes a 4-substituted catechol structure compound, having, at position 4 of its catechol ring, an electron-donating substituent R other than a hydrocarbon group, or a salt thereof. The 4-substituted catechol structure compound is preferably 4-aminocatechol or 1,2,4-benzenetriol. Examples of tauopathies to which this inhibitor is applicable include AD, Down's syndrome, frontotemporal dementia, cotricobasal degeneration (CBD) and progressive supranuclear palsy (PSP).

Abstract: A tau aggregation inhibitor can sufficiently inhibit a tau protein from aggregating in cells. The inhibitor includes a 4-substituted catechol structure compound, having, at position 4 of its catechol ring, an electron-donating substituent R other than a hydrocarbon group, or a salt thereof. The 4-substituted catechol structure compound is preferably 4-aminocatechol or 1,2,4-benzenetriol. Examples of tauopathies to which this inhibitor is applicable include AD, Down's syndrome, frontotemporal dementia, cotricobasal degeneration (CBD) and progressive supranuclear palsy (PSP).

Abstract: Disclosed is a ruthenium-phosphine complex represented by formula (I):?{RuX(L)}.sub.2 (.mu.-X).sub.3 !.sup.- ?R.sub.2 NH.sub.2 !.sup.+(I)wherein R is hydrogen, an alkyl group having 1 to 5 carbon atoms, a cycloalkyl group, a substituted or unsubstituted phenyl group or a substituted or unsubstituted benzyl group; X is halogen; and L is an optically active or inactive tertiary phosphine. A process for preparing the complex (I) is also disclosed, which comprises (A) reacting a ruthenium complex represented by formula: ?RuX(arene)(L)!X (wherein arene is a substituted or unsubstituted phenyl group) and an ammonium salt represented by formula (III): R.sub.2 NH.HX, or (B) reacting a ruthenium complex represented by formula: ?RuX.sub.2 (arene)!.sub.2, a tertiary phosphine represented by L, and an ammonium salt (III). The complex (I) useful as a catalyst for general syntheses or asymmetric syntheses can be obtained easily in good yield.

Abstract: An optically active 2-diphenylphosphinomethyl-2'-diphenylphosphinyl-1,1'-binaphthalene derivative represented by the following general formula (I) ##STR1## wherein R represents a phenyl group, a tolyl group, an anisyl group or a chlorophenyl group, and a process for the production of optically active substances in which the above compound and a transition metal compound are used. The asymmetric diphosphine of the present invention is related to the creation of novel compounds, which is excellent as a ligand for asymmetric synthesis use. When the above compound is used together with a transition metal compound such as of ruthenium, rhodium or the like, it shows markedly excellent properties as the catalyst of asymmetric hydrogenation and the like reactions, in terms of selectivity, conversion ratio, catalytic activity and the like.

Abstract: A syringe is arranged with a frangible connection between a conical needle head mounting a needle member to permit removal of the head and associated needle member permitting projection of the needle into the syringe body subsequent to its use. A modification of the invention includes a container to receive used needle bodies, with indicator dye contained within the capsule within the needle body that is ruptured upon insertion of the needle therewithin for indication of a used needle within a storage container.