Patents by Inventor Tetsuro Ikegami

Tetsuro Ikegami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rift valley fever vaccine
    Patent number: 11643640
    Abstract: Certain embodiments are directed to an improved RVF vaccine for human use, and method for producing the same.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 9, 2023
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Tetsuro Ikegami
  • RIFT VALLEY FEVER VACCINE
    Publication number: 20210108181
    Abstract: Certain embodiments are directed to an improved RVF vaccine for human use, and method for producing the same.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 15, 2021
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Tetsuro IKEGAMI
  • Recombinant rift valley fever virus encoding a dominant-negative inhibitor of DSRNA-dependent protein kinase in the NSS region
    Patent number: 9144605
    Abstract: Certain embodiments of the invention are directed to methods and compositions comprising a Rift Valley fever virus (RVFV) wherein a heterologous nucleic acid encoding a dsRNA-dependent protein kinase (PKR) inhibitor is inserted into the NSs region of the virus.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: September 29, 2015
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Tetsuro Ikegami, Birte Kalveram, Sabarish Indran, Olga Lihoradova, Alexander Freiberg
  • INHIBITORS OF DSRNA-DEPENDENT PROTEIN KINASE (PKR) AS ENHANCERS OF BUNYAVIRUS LIVE-ATTENUATED VACCINES
    Publication number: 20130243815
    Abstract: Certain embodiments of the invention are directed to methods and compositions for inhibiting dsRNA-dependent protein kinase (PKR) and augmenting the immunogenicity of Bunyavirus live-attenuated vaccines.
    Type: Application
    Filed: February 14, 2013
    Publication date: September 19, 2013
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Tetsuro Ikegami, Birte Kalveram, Sabarish Indran, Olga Lihoradova, Alexander Freiberg
  • Reverse genetic system for rift valley fever virus and uses thereof
    Patent number: 8084248
    Abstract: The present invention describes a reverse genetic system for Phlebovirus such as Rift Valley fever virus. This system comprised of RNA expression plasmids and protein expression plasmids. Additionally, the present invention also discloses the modification of this system to generate a recombinant virus that expresses a non-viral foreign gene. Furthermore, the present invention discloses the use of this system in the development of anti-Rift Valley fever virus vaccines, screening of antivirals testing for anti RVF immune response and developing marker vaccines for Rift Valley fever virus. We also claim the utility of this approach to other phleboviruses.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: December 27, 2011
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Shinji Makino, Tetsuro Ikegami, Clarence J. Peters, Sungyong Won
  • Reverse genetic system for Rift Valley fever virus and uses thereof
    Publication number: 20070122431
    Abstract: The present invention describes a reverse genetic system for Phlebovirus such as Rift Valley fever virus. This system comprised of RNA expression plasmids and protein expression plasmids. Additionally, the present invention also discloses the modification of this system to generate a recombinant virus that expresses a non-viral foreign gene. Furthermore, the present invention discloses the use of this system in the development of anti-Rift Valley fever virus vaccines, screening of antivirals testing for anti RVF immune response and developing marker vaccines for Rift Valley fever virus. We also claim the utility of this approach to other phleboviruses.
    Type: Application
    Filed: November 30, 2006
    Publication date: May 31, 2007
    Inventors: Shinji Makino, Tetsuro Ikegami, Clarence Peters