Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.

Abstract: Suppressing deterioration in analysis accuracy on an image. A biological specimen detection system includes: a stage (20) capable of supporting a sample including a biological specimen; an observation system (40) that includes an objective lens (44) and observes the sample in a line-shaped visual field that is a part of a visual field through the objective lens; a signal acquisition unit (1) that acquires an image signal obtained from the sample by scanning the observation system in a first direction orthogonal to the line-shaped visual field; and a correction unit (24) that corrects distortion of a captured image based on the image signal on a basis of a positional relationship between an optical axis center of the objective lens and the line-shaped visual field.

Abstract: A data generation method according to an embodiment includes: an imaging step (S10) of capturing, for each of lines for scanning an imaging target, a plurality of fluorescence images generated by the imaging target for a respective plurality of fluorescence wavelengths and acquiring data of the captured plurality of fluorescence images in arrangement order of the lines and a rearrangement step (S12) of changing the arrangement order of the data of the plurality of fluorescence images acquired in the imaging step from the arrangement order of the lines to arrangement order of for each of the plurality of fluorescence wavelengths.

Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.

Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.

Abstract: High-speed and high-accuracy focus adjustment is achieved. A microscope system (1) includes: an irradiation unit (18) that emits line illumination parallel to a first direction; a stage (26) that supports a specimen and is movable in a second direction perpendicular to the first direction; a phase difference acquisition unit (60I) that acquires phase difference information regarding an image of light emitted from the specimen by being irradiated with the line illumination; an objective lens (22) that focuses the line illumination on the specimen; a derivation unit (60E) that derives relative position information between the objective lens and the specimen based on the phase difference information; and a movement control unit (60F) that causes at least one of the objective lens and the stage to move in a third direction vertical to each of the first direction and the second direction based on the relative position information.

Abstract: A microscope device includes an opening (31) that includes a first slit and a second slit through which a plurality of pieces of light from an observation target resulting from a plurality of pieces of irradiation light emitted to the observation target and having different wavelengths pass, a dispersion element that wavelength-disperses the plurality of pieces of light passing through the opening (31), and an imaging element (32) that receives the plurality of pieces of light wavelength-dispersed by the dispersion element. The imaging element (32) performs light reception so that, as for the plurality of pieces of light wavelength-dispersed, zeroth-order light of light passing through the second slit and first-order light of light passing through the first slit do not overlap with each other.

Abstract: A medical system (1) includes: an irradiation means (2) that irradiates a subject with coherent light; an imaging means (3) that captures an image of reflected light of the coherent light from the subject; an acquiring means (411) that acquires a speckle image from the imaging means (3); a calculating means (412) that performs, for each pixel of the speckle image, on the basis of luminance values of that pixel and surrounding pixels, statistical processing and calculation of a predetermined index value; a determining means (413) that determines, for the each pixel, whether or not a mean of the luminance values used in the calculation of the index value is in a predetermined range; a generating means (414) that generates a predetermined image on the basis of the index values; and a display control means (415) that identifiably displays, in displaying the predetermined image on a display means, a portion of pixels each having a mean of the luminance values, the mean being outside the predetermined range.

Abstract: The flow rate of light scattering fluid is measured more easily and at a higher speed. A flow rate measuring method according to the present disclosure includes: generating two or more speckle images by continually imaging light scattering fluid to be measured, while defining time shorter than spatial correlation disappearance time corresponding to time in which spatial correlation between speckle patterns generated by the light scattering fluid disappears as exposure time, at a time interval shorter than the spatial correlation disappearance time; and calculating direction and speed of flow of the light scattering fluid from time variation of the speckle patterns between the two or more speckle images, in which the speckle images are imaged by using an imaging device mounted with an area sensor and a pixel group of a part of the area sensor or by using an imaging device mounted with a line sensor.

Abstract: A medical system (1) includes first light irradiation means (11) for irradiating an image capturing target with coherent light, image capturing means (12) for capturing a speckle image obtained from scattered light caused by the image capturing target irradiated with the coherent light, speckle contrast calculation means (1312) for calculating a speckle contrast value for each pixel on the basis of the speckle image, motion detection means (1311) for detecting motion of the image capturing target, speckle image generation means (1313) for generating a speckle contrast image on the basis of the speckle contrast value and the motion of the image capturing target detected by the motion detection means, and display means (14) for displaying the speckle contrast image.

Abstract: A medical observation system (3) including: an imaging portion (303) configured to capture an image of an affected area; a detecting portion (311) configured to extract; a movement of a treatment tool held in a vicinity of the affected area based on images of the affected area having been sequentially captured by the imaging portion and to detect a movement of the affected area based on a result of the extraction; and a control portion (301) configured to control processing related to observation of the affected area in accordance with a detection result of the movement of the affected area.

Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.

Abstract: A control device according to an embodiment of the present technology includes an acquisition section, a block control section, and a calculator. The acquisition section acquires an image signal of a tissue of a living body irradiated with laser light and on which image-capturing has been performed. The block control section controls a size of a pixel block according to an image-capturing condition for the image-capturing on the tissue of a living body. The calculator calculates speckle data based on the acquired image signal, using the pixel block of which the size is controlled.

Abstract: A medical observation system (2, 3) includes: a light source (223) configured to illuminate an affected body part; a branching optical system (213) configured to separate light from the affected body part into a plurality of polarized lights having different polarization directions; a detection unit (313) configured to individually detect the plurality of polarized lights; an arithmetic operation unit (305) configured to individually calculate speckle contrasts on the basis of detection results of the plurality of polarized lights; and a processing unit (303) configured to execute processing with respect to observation of the affected body part on the basis of at least any of calculation results of the speckle contrasts corresponding to the plurality of polarized lights.

Abstract: To provide an image analyzing technology capable of obtaining an image with less shading and with enough speckle contrast. An imaging apparatus includes: a light source that irradiates an imaging object with coherent light with a first irradiation condition and a second irradiation condition; a speckle imaging unit that captures a first speckle image obtained from scattered light of the imaging object irradiate at the first irradiation condition, and a second speckle image obtained from scattered light of the imaging object irradiate at the second irradiation condition; and an information processing unit that separates speckle images at boundaries of average luminance difference formed in the first speckle image and the second speckle image, connecting the separaged speckle images at the boundaries, and analyzes the combined speckle combined image.

Abstract: The present disclosure relates to an image processing apparatus and method and an image processing system that enable highly accurate observation. An intra-frame operation unit performs, as online processing, image processing of speckles generated by irradiation with laser light on a captured image in accordance with a relationship between an image output frame rate and a sampling rate. A high-precision operation unit performs, as offline processing, the image processing of speckles on the captured image in accordance with the relationship between an image output frame rate and a sampling rate. The present disclosure may be applied to an image processing system including, for example, a speckle imaging apparatus.

Abstract: The flow rate of light scattering fluid is measured more easily and at a higher speed. A flow rate measuring method according to the present disclosure includes: generating two or more speckle images by continually imaging light scattering fluid to be measured, while defining time shorter than spatial correlation disappearance time corresponding to time in which spatial correlation between speckle patterns generated by the light scattering fluid disappears as exposure time, at a time interval shorter than the spatial correlation disappearance time; and calculating direction and speed of flow of the light scattering fluid from time variation of the speckle patterns between the two or more speckle images, in which the speckle images are imaged by using an imaging device mounted with an area sensor and a pixel group of a part of the area sensor or by using an imaging device mounted with a line sensor.

Abstract: To provide an image analyzing technology capable of obtaining an image with less shading and with enough speckle contrast. An imaging apparatus includes: a light source that irradiates an imaging object with coherent light with a first irradiation condition and a second irradiation condition; a speckle imaging unit that captures a first speckle image obtained from scattered light of the imaging object irradiate at the first irradiation condition, and a second speckle image obtained from scattered light of the imaging object irradiate at the second irradiation condition; and an information processing unit that separates speckle images at boundaries of average luminance difference formed in the first speckle image and the second speckle image, connecting the separaged speckle images at the boundaries, and analyzes the combined speckle combined image.

Abstract: Provided is an imaging technique capable of detecting a focus even in an imaging apparatus of a speckle image. The imaging apparatus includes a coherent light source that irradiates an imaging object with coherent light, an incoherent light source that irradiates the imaging object with incoherent light, a speckle imaging unit that captures a speckle image obtained from scattered light of the imaging object irradiated with the coherent light, a non-speckle imaging unit that captures a non-speckle image obtained from reflected light of the imaging object irradiated with the incoherent light, and a focus detection unit that detects a focus of the speckle imaging unit on the basis of a focal position of the non-speckle imaging unit.

Abstract: There is provided an imaging technology using a speckle, which is capable of eliminating cross-talk. In the present technology, there is provided an imaging system including: a first light source that irradiates an imaging target with coherent light of a first wavelength band; a second light source that irradiates the imaging target with incoherent light of a second wavelength band; an image capturing unit that captures a speckle image and a non-speckle image, the speckle image being obtained from scattered light of the imaging target irradiated with the coherent light, the non-speckle image being obtained from reflected light of the imaging target irradiated with the incoherent light; and a cross-talk elimination unit that eliminates cross-talk that occurs between the captured speckle image and the captured non-speckle image.