Abstract: One embodiment provides a bar-handle vehicle brake control apparatus. The control apparatus includes an acceleration acquiring part and a control unit. The acceleration acquiring part acquires a tangential acceleration at a point where a straight line which connects a gravity center of a bar-handle vehicle and a front wheel axle intersects a circle which is centered at the front wheel axle. The control unit controls a front wheel brake based on the tangential acceleration.

Abstract: A handheld engine-driven cutter is provided with a disk blade and a main body that drives the disk blade. The main body comprises a four-stroke engine, an oil supplying opening from which engine oil is supplied, and an oil exhausting opening from which the engine oil is exhausted. In this engine cutter, the oil supplying opening and the oil exhausting opening are both disposed on one side of the main body where one end of a driving axis of the four-stroke engine is located.

Abstract: A vehicle rear wheel lift tendency judgment device: includes a first deceleration obtaining device for obtaining a first deceleration along a first straight line, being a component in a first direction of an acceleration on a center of gravity, and a second deceleration obtaining device for obtaining a second deceleration along a second straight line, being a component in a second direction of the acceleration; judges that a rear wheel tends to be lifted, when the first deceleration is greater in the first direction than a first threshold, or when the second deceleration is greater in the second direction than a second threshold; and performs at least one of setting for shifting the first threshold in a direction opposite to the first direction and setting for shifting the second threshold in a direction opposite to the second direction, when a second-deceleration change rate being a change amount in the second deceleration per unit time becomes greater in the second direction than a change-rate threshold, en

Abstract: A four-stroke engine is provided to lubricate driving parts including a crankshaft and valve operating members while circulating oil, using pressure fluctuation in a crank chamber, the pressure fluctuation being caused by reciprocating motion of a piston. A cam driving parts move with rotation of the crankshaft; a driving chamber and a rocker chamber are connected to one another; the rocker chamber is connected to the crank chamber and a gas-liquid separator; the oil accumulated in a tank is sucked up into the crank chamber and circulated through each part of the four-stroke engine; the crank chamber and the driving chamber are connected to one another via a communicating passage and a return passage; and the crank chamber and the driving chamber connected to one another via the return passage communicate with one another only when the piston is located in a vicinity of the top dead center.

Abstract: Provided is an aqueous pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (compound (I)) or a salt thereof, which shows improved water solubility of compound (I) or a salt thereof achieved by addition of substituted ?-cyclodextrin. The present invention provides a pharmaceutical preparation comprising compound (I) or a salt thereof, and substituted ?-cyclodextrin.

Abstract: Provided is siRNA effective for the treatment of fibrosis and a pharmaceutical containing the siRNA.

Abstract: A handheld engine-driven cutter is provided with a disk blade and a four-stroke engine that drives the disk blade. By employing the four-stroke engine, exhaustion of unburned gas and fuel consumption can be reduced. The engine cutter is further provided with a filter through which air provided to the four-stroke engine passes, a carburetor that mixes fuel and the air that passed through the filter, and a casing that houses the filter and the carburetor. The filter and the carburetor are arranged to align on a straight line along a direction of flow of the air passing through the filter and the carburetor.

Abstract: One embodiment provides a bar-handle vehicle brake control apparatus. The control apparatus includes an acceleration acquiring part and a control unit. The acceleration acquiring part acquires a tangential acceleration at a point where a straight line which connects a gravity center of a bar-handle vehicle and a front wheel axle intersects a circle which is centered at the front wheel axle. The control unit controls a front wheel brake based on the tangential acceleration.

Abstract: Provided is siRNA effective for the treatment of fibrosis and a pharmaceutical containing the siRNA. An siRNA having a full length of 30 or fewer nucleotides and targeting a sequence consisting of 17 to 23 consecutive bases selected from the group consisting of bases at positions 1285 to 1318, bases at positions 1398 to 1418, bases at positions 1434 to 1463, bases at positions 1548 to 1579, bases at positions 1608 to 1628, bases at positions 1700 to 1726, bases at positions 1778 to 1798, bases at positions 1806 to 1826, and bases at positions 1887 to 1907 of SEQ ID NO: 1.

Abstract: When a p-layer 4 composed of GaN is maintained at ordinary temperature and TNO is sputtered thereon by an RF magnetron sputtering method, a laminated TNO layer 5 is in an amorphous state. Then, there is included a step of thermally treating the amorphous TNO layer in a reduced-pressure atmosphere where hydrogen gas is substantially absent to thereby crystallize the TNO layer. At the sputtering, an inert gas is passed through together with oxygen gas, and volume % of the oxygen gas contained in the gas passed through is 0.10 to 0.15%. In this regard, oxygen partial pressure is 5×10?3 Pa or lower. The temperature of the thermal treatment is 500° C. for about 1 hour.

Abstract: A lubrication apparatus for a four-stroke engine that prevents lubrication failure from occurring around the crankshaft and reliably prevents oil from remaining in a valve operating chamber includes: an intake part positioned below the level of an oil A in an oil reservoir even if the oil reservoir is tilted and the level of the oil A changes; an oil feeding passageway that sucks up the oil A from the intake part and supplies the oil A to the crank chamber; and an direct passageway that allows communication between a valve operating chamber and a crank chamber when a negative pressure is created in the crank chamber. Open end parts of the oil feeding passageway and the direct passageway which are open in the crank chamber are provided to open as the piston moves from a position near the top dead center to the top dead center.

Abstract: A brake control system includes at least a pair of brake systems respectively connected to a pair of brake operating members L1, L2, and a control unit 10 for controlling the brake forces of the pair of brake systems interlockingly according to a predetermined distribution ratio by operating one of the pair of brake operating members L1, L2. The control unit 10 executes a decreasing control on the brake forces in such a manner that, when releasing the pair of brake operating members L1, L2, the control unit 10 decreases both of the brake forces together, even in a state where the control unit performs the interlocking control so as to decrease the brake force of one of the brake system as the brake force of the other of the brake system is increased in accordance with the predetermined distribution ratio.

Abstract: A liquid tank cap for a working machine engine is provided. The liquid tank cap opens and closes a filling opening of a tip end portion of a refilling pipe of a liquid tank. The liquid tank cap includes an upper wall that covers the filling opening, a fitting portion that engages with an inner surface of the filling opening and protrudes from the upper wall, and a peripheral wall that covers an outer circumference of the refilling pipe in a state where the liquid tank cap is attached to the filling opening.

Abstract: Provided is siRNA effective for the treatment of fibrosis and a pharmaceutical containing the siRNA. An siRNA having a full length of 30 or fewer nucleotides and targeting a sequence consisting of 17 to 23 consecutive bases selected from the group consisting of bases at positions 1285 to 1318, bases at positions 1398 to 1418, bases at positions 1434 to 1463, bases at positions 1548 to 1579, bases at positions 1608 to 1628, bases at positions 1700 to 1726, bases at positions 1778 to 1798, bases at positions 1806 to 1826, and bases at positions 1887 to 1907 of SEQ ID NO: 1.

Abstract: A four-stroke engine is provided to lubricate driving parts including a crankshaft and valve operating members while circulating oil, using pressure fluctuation in a crank chamber, the pressure fluctuation being caused by reciprocating motion of a piston. A cam driving parts move with rotation of the crankshaft; a driving chamber and a rocker chamber are connected to one another; the rocker chamber is connected to the crank chamber and a gas-liquid separator; the oil accumulated in a tank is sucked up into the crank chamber and circulated through each part of the four-stroke engine; the crank chamber and the driving chamber are connected to one another via a communicating passage and a return passage; and the crank chamber and the driving chamber connected to one another via the return passage communicate with one another only when the piston is located in a vicinity of the top dead center.

Abstract: An object of the present invention is to provide a muffler mounting structure configured to be able to prevent fastening parts from slackening by reducing the thermal conductivity from an exhaust port to the muffler mounting bosses and an engine including the muffler mounting structure. An engine of the present invention 100 includes a cylinder block 101 or the cylinder head 10 constitutes a combustion chamber 105 with a piston 104, an exhaust port configured to communicate with the combustion chamber, and a muffler mounted to an outlet of the exhaust port, wherein the muffler is mounted with a muffler mounting boss into which a fixing part is fitted, and the muffler mounting boss is connected to a fin formed in the cylinder.

Abstract: A lubricating device for a four-stroke engine is provided that circulates oil while lubricating each part in a valve operating chamber and a crank chamber by supplying the oil to the valve operating chamber and the crank chamber using pressure fluctuation in the crank chamber, the pressure fluctuation being caused by reciprocating motion of a piston. The valve operating chamber is formed by mounting a valve operating chamber cover, and a suction passageway that sucks the oil in the valve operating chamber is provided by forming a groove on an inner surface of the valve operating chamber cover and sealing the groove with a sealing member shaped to fit the groove.

Abstract: An engine includes a crank chamber in which pressure fluctuation occurs and a carburetor including a diaphragm fuel pump. The diaphragm fuel pump includes a pump chamber configured to suck in and eject fuel and a diaphragm chamber to which a pressure that drives the pump chamber is supplied. The diaphragm chamber and the crank chamber communicate with one another in a state in which a negative pressure is created in the crank chamber.

Abstract: A lubrication apparatus for a four-stroke engine (1) is provided that prevents lubrication failure from occurring around the crankshaft and reliably prevents oil from remaining in a valve operating chamber (30). The lubrication apparatus for the four-stroke engine (1) includes: an intake part (55) positioned below the level of an oil A in an oil reservoir (7) even if the oil reservoir (7) is tilted and the level of the oil A changes; an oil feeding passageway (54) that sucks up the oil A from the intake part (55) and supplies the oil A to the crank chamber (5a); and an direct passageway (47) that allows communication between a valve operating chamber (30) and a crank chamber (5a) when a negative pressure is created in the crank chamber (5a). Open end parts (47a, 54a) of the oil feeding passageway (54) and the direct passageway (47) which are open in the crank chamber (5a) are provided to open as the piston (13) moves from a position near the top dead center to the top dead center.

Abstract: An object of the present invention is to provide a muffler mounting structure configured to be able to prevent fastening parts from slackening by reducing the thermal conductivity from an exhaust port to the muffler mounting bosses and an engine including the muffler mounting structure. An engine of the present invention 100 includes a cylinder block 101 or the cylinder head 10 constitutes a combustion chamber 105 with a piston 104, an exhaust port configured to communicate with the combustion chamber, and a muffler mounted to an outlet of the exhaust port, wherein the muffler is mounted with a muffler mounting boss into which a fixing part is fitted, and the muffler mounting boss is connected to a fin formed in the cylinder.