Patents by Inventor Tetsuya HAYAMA

Tetsuya HAYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oral preparation of obeticholic acid
    Patent number: 11413295
    Abstract: The present invention pertains to an oral preparation having exceptional elutability, the oral preparation containing obeticholic acid or a pharmacologically acceptable salt thereof, a water-soluble excipient, a disintegrating agent, and a water-soluble polymer binder, wherein the oral preparation is a quick-release tablet.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: August 16, 2022
    Assignee: INTERCEPT PHARMACEUTICALS, INC.
    Inventors: Mitsuhiro Matono, Tetsuya Hayama
  • Film-coated tablet having high chemical stability of active ingredient
    Patent number: 11331273
    Abstract: The present invention relates to a film-coated tablet having a high chemical stability of an active ingredient, said film-coated tablet comprising: (a) a tablet core containing obeticholic acid or a pharmaceutically acceptable salt thereof; and (b) a coating layer, which is provided on the surface of the tablet core, containing a film base and being substantially free from any plasticizer or containing at least one kind of specific plasticizer.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: May 17, 2022
    Inventors: Mitsuhiro Matono, Tetsuya Hayama
  • Dispersion of Pluripotent Stem Cells, and Pluripotent Stem Cell Product and Method for Producing Same
    Publication number: 20210230558
    Abstract: An object of the present invention is to provide a dispersion of pluripotent stem cells and a pluripotent stem cell product having a suitable quality as a pharmaceutical or a raw material for producing a pharmaceutical which can be stored and distributed, and a method for producing the same. The method for producing a pluripotent stem cell product of the present invention comprises (1) culturing pluripotent stem cells in an undifferentiation maintenance medium; (2) suspending the pluripotent stem cells cultured in step (1) in a first medium for suspending cells containing a ROCK inhibitor; (3) replacing the medium for suspending cells of a suspension obtained in step (2) with a medium for cryopreservation to obtain a cell dispersion solution consisting of the medium for cryopreservation and the pluripotent stem cells dispersed in the medium for cryopreservation; and (4) filling the cell dispersion solution obtained in step (3) into an airtight container so as to be in an airtight state.
    Type: Application
    Filed: July 10, 2019
    Publication date: July 29, 2021
    Applicants: Sumitomo Dainippon Pharma Co., Ltd., Sumitomo Chemical Company, Limited
    Inventors: Atsushi Kuwahara, Naoki Takamura, Ayaka Fujiki, Tetsuya Hayama, Hidetaka Ohara
  • FILM-COATED TABLET HAVING HIGH CHEMICAL STABILITY OF ACTIVE INGREDIENT
    Publication number: 20200268671
    Abstract: The present invention relates to a film-coated tablet having a high chemical stability of an active ingredient, said film-coated tablet comprising: (a) a tablet core containing obeticholic acid or a pharmaceutically acceptable salt thereof; and (b) a coating layer, which is provided on the surface of the tablet core, containing a film base and being substantially free from any plasticizer or containing at least one kind of specific plasticizer.
    Type: Application
    Filed: March 30, 2017
    Publication date: August 27, 2020
    Inventors: Mitsuhiro MATONO, Tetsuya Hayama
  • ORAL PREPARATION HAVING EXCEPTIONAL ELUTABILITY
    Publication number: 20190216826
    Abstract: The present invention pertains to an oral preparation having exceptional elutability, the oral preparation containing obeticholic acid or a pharmacologically acceptable salt thereof, a water-soluble excipient, a disintegrating agent, and a water-soluble polymer binder.
    Type: Application
    Filed: March 30, 2017
    Publication date: July 18, 2019
    Inventors: Mitsuhiro MATONO, Tetsuya HAYAMA