Abstract: A mold of the present disclosure is used when forging a billet having a rod shape, and the mold includes: a lower mold having a groove portion for housing the billet; an upper mold having a pressing portion engaged with the groove portion and that presses the billet; and a guide portion disposed in the groove portion or the pressing portion and that guides a flow of a material of the billet in a longitudinal direction of the billet. In a state in which the groove portion and the pressing portion are engaged, in a direction in which the groove portion extends, a protruding amount of a top portion of the guide portion to an inner side of the groove portion is larger than a protruding amount of end portions on both sides sandwiching the top portion of the guide portion to the inner side of the groove portion.

Abstract: A mold of the present disclosure is used when forging a billet having a rod shape, and the mold includes: a lower mold having a groove portion for housing the billet; an upper mold having a pressing portion engaged with the groove portion and that presses the billet; and a guide portion disposed in the groove portion or the pressing portion and that guides a flow of a material of the billet in a longitudinal direction of the billet. In a state in which the groove portion and the pressing portion are engaged, in a direction in which the groove portion extends, a protruding amount of a top portion of the guide portion to an inner side of the groove portion is larger than a protruding amount of end portions on both sides sandwiching the top portion of the guide portion to the inner side of the groove portion.

Abstract: In the intermediate process state estimation method, two generators are used, and as well as inputting a common input noise to the respective generators, a label corresponding to a certain step is input to one generator and a label corresponding to a step different from the certain step is input to the other generator. Then, one of generation data and training data generated by the respective generators is randomly input to a discriminator, and the generators and the discriminator learn in an adversarial manner from the discrimination result in the discriminator. Then, an input noise corresponding to a desired final state and a label corresponding to a step where it is desired that an intermediate process state be estimated are input to the learned generator to estimate the intermediate process state based on the generation data generated by the generator.

Abstract: In the intermediate process state estimation method, two generators are used, and as well as inputting a common input noise to the respective generators, a label corresponding to a certain step is input to one generator and a label corresponding to a step different from the certain step is input to the other generator. Then, one of generation data and training data generated by the respective generators is randomly input to a discriminator, and the generators and the discriminator learn in an adversarial manner from the discrimination result in the discriminator. Then, an input noise corresponding to a desired final state and a label corresponding to a step where it is desired that an intermediate process state be estimated are input to the learned generator to estimate the intermediate process state based on the generation data generated by the generator.

Abstract: Sialyl Lewis X mimetics incorporating fucopeptides are synthesized and shown to mimic the configuration and essential functional groups of sialyl Lewis X in space. The fucopeptides exhibit substantially the same biological activity as sialyl Lewis X in the E-selectin binding assay and can be employed for blocking neutrophil inflamatory conditions.

Abstract: Sialyl Lewis.sup.x mimetic compounds are disclosed that are free of sialyl groups and glycosidically-linked fucosyl groups. These compounds exhibit about the same inhibition of selectin-medicated cellular adhesion as does sialyl Lewis.sup.x itself.

Abstract: Omega-deoxy-azapyranose compounds, processes of making and using the same are disclosed, as are a process of making omega-deoxy-azafuranose compounds.

Abstract: A process for the preparation of a 1,5-dideoxyazafuranose or 1,6-dideoxy-azapyranose is disclosed. In such a process, an azido-substituted .alpha.-ketose phosphate having a five- or a six-carbon chain is hydrogenated in the presence of a palladium catalyst. The carbon atom bearing the azido substituent and the carbon atom of the keto group of the .alpha.-ketose phosphate starting material are separated by two or three carbon atoms.