Patents by Inventor Tetsuya KITAGUCHI

Tetsuya KITAGUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic mutant suitable for homogeneous immunoassay method
    Patent number: 12188063
    Abstract: Provided as a mutant of ? glucuronidase suitable for homogeneous immunoassays is a ? glucuronidase mutant, wherein, in the amino acid sequence of Escherichia coli ? glucuronidase, methionine at position 516 is substituted with lysine, and tyrosine at position 517 is unsubstituted or substituted with a non-tyrosine aromatic amino acid.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: January 7, 2025
    Assignee: INSTITUTE OF SCIENCE TOKYO
    Inventors: Hiroshi Ueda, Jiulong Su, Tetsuya Kitaguchi, Yuki Ohmuro
  • HOMOGENEOUS IMMUNOASSAY METHOD USING PEPTIDE HAVING MULTIPLE FLUOROCHROMES JOINED THERETO
    Publication number: 20220244248
    Abstract: As a simple antigen detection approach using Q-body, provided is a kit for antigen detection, comprising: a first peptide conjugated with two fluorescent dyes capable of forming a FRET pair or a fluorescent dye and a luminescent material capable of forming a BRET pair, and an antibody fragment with a second peptide added thereto, wherein 1) one of the first peptide and the second peptide is positively charged, and the other peptide is negatively charged, and 2) the first peptide and the second peptide are capable of forming a coiled coil.
    Type: Application
    Filed: June 3, 2020
    Publication date: August 4, 2022
    Applicant: TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hiroshi UEDA, Tetsuya KITAGUCHI, Yuki OHMURO, Takanobu YASUDA, Akihito INOUE
  • ENZYMATIC MUTANT SUITABLE FOR HOMOGENEOUS IMMUNOASSAY METHOD
    Publication number: 20220119789
    Abstract: Provided as a mutant of ? glucuronidase suitable for homogeneous immunoassays is a ? glucuronidase mutant, wherein, in the amino acid sequence of Escherichia coli ? glucuronidase, methionine at position 516 is substituted with lysine, and tyrosine at position 517 is unsubstituted or substituted with a non-tyrosine aromatic amino acid.
    Type: Application
    Filed: January 23, 2020
    Publication date: April 21, 2022
    Applicant: TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hiroshi UEDA, Jiulong SU, Tetsuya KITAGUCHI, Yuki OHMURO