Abstract: The present invention relates to: a virus vector, which can effectively transfer a macromolecular antigenic peptide into target cells while maintaining a three-dimensional structure that is required for functioning as an antigen; and a vaccine utilizing the vector. Specifically, disclosed are: a virus vector, in which a nucleic acid encoding an antigenic polypeptide is integrated immediately 5? upstream of HN gene of an F gene-defective Paramyxoviridae virus gene, wherein the antigenic polypeptide is expressed as a fusion protein of 130 or more amino acid residues, fused with a TM sequence and/or a CT sequence derived from the virus.

Abstract: A wireless sensor system includes a sensor tag configured to include a radio frequency tag and a communication device configured to wirelessly communicate with one or more sensor tags. Each of the sensor tags is configured to receive a measurement signal from one or more sensor circuits and stores identification information capable of being distinguished from other sensor tags. The communication device includes a transmission means configured to transmit a command signal to the one or more sensor tags and the command signal includes designation information for designating a sensor target serving as an object. Each of the sensor tags generates measurement data on the basis of the measurement signal if the designation information included in the command signal received from the communication device matches its own stored identification information and starts transmission of a response signal including the generated measurement data when a predetermined response start condition is satisfied.

Abstract: Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.

Abstract: Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.

Abstract: The present invention discloses a cell system, as a host cell to be infected with an F gene-deficient virus, which can constitutively and stably express the F protein, and a method for producing an F gene-deficient virus by utilizing the cell. A non-proliferative human parainfluenza type 2 virus vector is produced by co-culturing an F gene-deficient human parainfluenza type 2 virus with a Vero cell having the F gene of human parainfluenza type 2 virus in such a manner that the F gene is non-inducibly expressed, and isolating viral particles from a culture supernatant.

Abstract: The present invention discloses a cell system, as a host cell to be infected with an F gene-deficient virus, which can constitutively and stably express the F protein, and a method for producing an F gene-deficient virus by utilizing the cell. A non-proliferative human parainfluenza type 2 virus vector is produced by co-culturing an F gene-deficient human parainfluenza type 2 virus with a Vero cell having the F gene of human parainfluenza type 2 virus in such a manner that the F gene is non-inducibly expressed, and isolating viral particles from a culture supernatant.

Abstract: It is possible to reduce a noise component mixed in an analog signal while suppressing increase of power consumption. An amplification unit amplifies the inputted analog signal and converts the amplified signal into a digital signal of a predetermined format for output. The amplification unit includes: an analog circuit unit for processing an analog signal; and a digital circuit unit for processing a digital signal; wherein the circuits are arranged on a substrate. The analog circuit unit includes: an amplification circuit for amplifying the inputted analog signal; and an LPF for cutting off a high frequency component of the amplified analog signal. The digital circuit unit includes: a rectification circuit which rectifies a waveform of the signal whose high-frequency component is cut off; and digital output circuit which converts the waveform-rectified signal into a digital signal of a predetermined format for output.

Abstract: A serializer is equipped with a plurality of input terminals into which a plurality of binary signals are input in parallel, and converts the plurality of input binary signals into serial binary signals and transmits the serial binary signals to an optical transmission module. One input terminal out of the plurality of input terminals is assigned as an input terminal for preventing bit continuation by inserting “1” signals or “0” signals into the serial binary signals so that a predetermined number of bits of the same value may not be inserted continuously. Due to this structure, bit continuation can be prevented even for a signal generating source with no coding function by a simple configuration without increasing cost and size.

Abstract: A transmission device has a light emitting element for converting an electric signal to an optical signal and transmitting the same, and a drive section for outputting the optical signal from the light emitting element and driving the light emitting element by providing the electric signal to the light emitting element. The electric signal provided by the drive section to the light emitting element is a waveform deformed signal having a waveform in which a time required for a fall is longer than a time required for a rise in a binary signal having a signal of high level and a signal of low level.

Abstract: Disclosed is a intranasal spray-type tuberculosis vaccine, which has a high prophylactic effect on human tuberculosis, particularly adult tuberculosis. The nebulizable tuberculosis vaccine for intranasal administration comprises a paramyxovirus gene (particularly rhPIV2) having, integrated therein, a gene encoding an ? antigen derived from an acid-fast bacterium (e.g., an ? antigen derived from Mycobacterium kansasii or Mycobacterium bovis BCG), an analogue of the gene, or a variant of the gene which has an equivalent function to that of the gene.

Abstract: It is possible to reduce a noise component mixed in an analog signal while suppressing increase of power consumption. An amplification unit amplifies the inputted analog signal and converts the amplified signal into a digital signal of a predetermined format for output. The amplification unit includes: an analog circuit unit for processing an analog signal; and a digital circuit unit for processing a digital signal; wherein the circuits are arranged on a substrate. The analog circuit unit includes: an amplification circuit for amplifying the inputted analog signal; and an LPF for cutting off a high frequency component of the amplified analog signal. The digital circuit unit includes: a rectification circuit which rectifies a waveform of the signal whose high-frequency component is cut off; and digital output circuit which converts the waveform-rectified signal into a digital signal of a predetermined format for output.

Abstract: A transmission device has a light emitting element for converting an electric signal to an optical signal and transmitting the same, and a drive section for outputting the optical signal from the light emitting element and driving the light emitting element by providing the electric signal to the light emitting element. The electric signal provided by the drive section to the light emitting element is a waveform deformed signal having a waveform in which a time required for a fall is longer than a time required for a rise in a binary signal having a signal of high level and a signal of low level.

Abstract: A serializer is equipped with a plurality of input terminals into which a plurality of binary signals are input in parallel, and converts the plurality of input binary signals into serial binary signals and transmits the serial binary signals to an optical transmission module. One input terminal out of the plurality of input terminals is assigned as an input terminal for preventing bit continuation by inserting “1” signals or “0” signals into the serial binary signals so that a predetermined number of bits of the same value may not be inserted continuously. Due to this structure, bit continuation can be prevented even for a signal generating source with no coding function by a simple configuration without increasing cost and size.