Abstract: The disclosure provides a semiconductor storage element which is provided with an error detection and correction circuit and, when an uncorrectable error occurs in the semiconductor storage element, capable of promptly transferring the occurrence to the outside, and provides a semiconductor storage device and a system-on-chip using the same. The semiconductor storage element includes a storage part storing data, an error detection and correction part detecting an error in the data stored in the storage part and correcting the error if possible, a monitoring part issuing an uncorrectable error signal when an uncorrectable error occurs in the error detection and correction part, and a terminal transmitting the uncorrectable error signal to the outside.

Abstract: A unit has a bottom surface, and first and second flange portions. A mounting plate has a first hook portion to be engaged with the first flange portion to control movement of the unit, having been mounted onto an upper plate surface, toward a front side in a depth direction and in a height direction; a second hook portion to be engaged with the second flange portion to control movement of the unit, having been mounted onto the upper plate surface, toward the front side in the depth direction and in the height direction; and a locking portion releasably engaged with the second flange portion to allow movement of the unit, being inserted or removed on the upper plate surface in the depth direction, and to control movement of the unit, having been mounted onto the upper plate surface, toward a rear side in the depth direction.

Abstract: An image generation system comprising a computer processor that functions as: an image input part configured to input an input image, the input image being a time-series image obtained by imaging an observed cell over time; and an image generator configured to generate a growth prediction image of the observed cell from the time-series image of the observed cell based on a first learned model, which has learned a relationship between the time-series image of a learning cell and a feature of the learning cell, and output the growth prediction image as an output image.

Abstract: A unit has a bottom surface, and first and second flange portions. A mounting plate has a first hook portion to be engaged with the first flange portion to control movement of the unit, having been mounted onto an upper plate surface, toward a front side in a depth direction and in a height direction; a second hook portion to be engaged with the second flange portion to control movement of the unit, having been mounted onto the upper plate surface, toward the front side in the depth direction and in the height direction; and a locking portion releasably engaged with the second flange portion to allow movement of the unit, being inserted or removed on the upper plate surface in the depth direction, and to control movement of the unit, having been mounted onto the upper plate surface, toward a rear side in the depth direction.

Abstract: The disclosure provides a semiconductor storage element which is provided with an error detection and correction circuit and, when an uncorrectable error occurs in the semiconductor storage element, capable of promptly transferring the occurrence to the outside, and provides a semiconductor storage device and a system-on-chip using the same. The semiconductor storage element includes a storage part storing data, an error detection and correction part detecting an error in the data stored in the storage part and correcting the error if possible, a monitoring part issuing an uncorrectable error signal when an uncorrectable error occurs in the error detection and correction part, and a terminal transmitting the uncorrectable error signal to the outside.

Abstract: An optical analysis device includes a light source, a beam shaping unit, a relative movement unit, a photodetector, and a position detector. The light source unit generates a light beam. The beam shaping unit forms a flat beam portion. The relative movement unit is configured to cause the flat beam portion and a test sample including marker particles to relatively move in a minor axis direction of the flat beam portion. The photodetector is configured to detect a light intensity and a light emitting position in a plane orthogonal to the minor axis direction. The position detector is capable of detecting spatial positions of the marker particles on the basis of information on a relative movement amount of the flat beam portion, information on the light intensity and the light emitting position, and a change of the light intensity generated according to a relative movement of the flat beam portion.

Abstract: In the scanning molecule counting method of measuring light intensity from a light detection region while moving the position of the light detection region of a confocal or multiphoton microscope in a sample solution containing light-emitting particles, generating time series light intensity data and detecting each of signals of the light-emitting particles individually in the data, wherein the light-emitting particles are formed by binding to a particle to be observed a light-emitting probe which emits light through binding to the particle to be observed and in which a stochastic transition between a non-light-emitting state and a light-emitting state occurs in the unbound state, the moving speed of the position of the light detection region is adjusted to make the time during which the unbound probe is encompassed by the moving light detection region longer than an average lifetime during which the probe is in the light-emitting state.

Abstract: An optical analysis device includes a light source, a beam shaping unit, a relative movement unit, a photodetector, and a position detector. The light source unit generates a light beam. The beam shaping unit forms a flat beam portion. The relative movement unit is configured to cause the flat beam portion and a test sample including marker particles to relatively move in a minor axis direction of the flat beam portion. The photodetector is configured to detect a light intensity and a light emitting position in a plane orthogonal to the minor axis direction. The position detector is capable of detecting spatial positions of the marker particles on the basis of information on a relative movement amount of the flat beam portion, information on the light intensity and the light emitting position, and a change of the light intensity generated according to a relative movement of the flat beam portion.

Abstract: A method for detecting a target nucleic acid molecule of the present invention includes a step of associating a first and third probes labeled with a first fluorescent substance which is an energy donor with a second probe labeled with a second fluorescent substance which is an energy acceptor to form an associate in a nucleic acid molecule; and a step of emitting light with an excitation wavelength of the first fluorescent substance to the associate to detect the target nucleic acid molecule using fluorescence released from the second fluorescent substance in the associate as an indicator, wherein a region associating with the second probe is between a region associating with the first probe and a region associating with the third probe in the target nucleic acid molecule.

Abstract: There is provided an optical analysis technique of detecting light of a light-emitting particle in a sample solution in the scanning molecule counting method using the light measurement with a confocal or multiphoton microscope, for suppressing the scattering in detected results of signals of light of light-emitting particles smaller and achieving the improvement of accuracy. The inventive technique comprises moving the position of a light detection region along a predetermined route for multiple circulation times by changing the optical path of the optical system; detecting light from the light detection region and generating time series light intensity data during the moving of the light detection region and detecting individually a signal indicating light from each light-emitting particle existing in the predetermined route using the time series light intensity data obtained in the circulating movements of the light detection region of multiple times.

Abstract: There is provided a microscopic observation technique capable of detecting a light-emitting object or a light-emitting particle moving in a thick sample by the scanning molecule counting method. In the inventive technique, the light from a light detection region of is detected the optical system of a confocal or multiphoton microscope is detected with while moving the light detection region in each observed subregion obtained by dividing a region to be observed into plural regions; the signal of the light from a light-emitting particle is individually detected; and the position of the light-emitting particle corresponding to the detected signal is determined in the region to be observed. The moving of the position of the light detection region in each observed subregion is performed continuously in at least two directions or and/or continuously multiple times in each observed subregion.

Abstract: There is provided a microscopic observation technique capable of detecting a light-emitting object or a light-emitting particle moving in a thick sample by the scanning molecule counting method. In the inventive technique, the light from a light detection region of is detected the optical system of a confocal or multiphoton microscope is detected with while moving the light detection region in each observed subregion obtained by dividing a region to be observed into plural regions; the signal of the light from a light-emitting particle is individually detected; and the position of the light-emitting particle corresponding to the detected signal is determined in the region to be observed. The moving of the position of the light detection region in each observed subregion is performed continuously in at least two directions or and/or continuously multiple times in each observed subregion.

Abstract: In the scanning molecule counting method of measuring light intensity from a light detection region while moving the position of the light detection region of a confocal or multiphoton microscope in a sample solution containing light-emitting particles, generating time series light intensity data and detecting each of signals of the light-emitting particles individually in the data, wherein the light-emitting particles are formed by binding to a particle to be observed a light-emitting probe which emits light through binding to the particle to be observed and in which a stochastic transition between a non-light-emitting state and a light-emitting state occurs in the unbound state, the moving speed of the position of the light detection region is adjusted to make the time during which the unbound probe is encompassed by the moving light detection region longer than an average lifetime during which the probe is in the light-emitting state.

Abstract: In the scanning molecule counting method using the light measurement with a confocal microscope or a multiphoton microscope, a measuring time is optimized with suppressing the scattering in a result small irrespective of light-emitting particle concentrations. In the inventive technique of detecting and analyzing the light from an light-emitting particle, there are repeated processes of detecting the light intensity from a light detection region with moving the position of the light detection region of an optical system in a sample solution by changing the optical path of the optical system of the microscope, and detecting the signals of the light of light-emitting particles individually, and based on the time taken for the number of the signals from the light-emitting particles to reach a predetermined number, the light-emitting particle concentration in the sample solution is determined.

Abstract: Left and right radiators in a saddle type vehicle are formed in a trapezoidal shape and disposed such that a shorter one of two side portions of each of the radiators which extend in parallel or substantially in parallel to each other as viewed in front elevation is positioned at the inner side in the vehicle widthwise direction. A longer one of the side portions is disposed at the outer side in the vehicle widthwise direction. Forward projections of an exhaust pipe projecting forwardly from an engine pass below the shorter side portions at the inner side in the vehicle widthwise direction of the radiators.

Abstract: In the scanning molecule counting method using optical measurement with a confocal or multiphoton microscope, there is provided a technique of computing a light-emitting particle concentration which changes with time and detecting a concentration change velocity or a reaction velocity. The inventive optical analysis technique of detecting light of light-emitting particles in a sample solution generates time series light intensity data of light from a light detection region detected with moving the position of the light detection region of the microscope in the sample solution; measures successively an interval of generation times of signals of the light-emitting particles detected in the time series light intensity data; and determines the concentration or concentration change velocity of the light-emitting particles, using the successively measured signal generation time intervals.

Abstract: There is provided optical analysis techniques in the scanning molecule counting method using the light measurement with a confocal or multiphoton microscope in which the measuring unit time in the light measurement is set to an appropriate value in order to surely detect an approximately bell shape profile of the signal of a light-emitting particle and avoid excessive increase data volume of time series light intensity data. The inventive optical analysis technique of detecting light of a light-emitting particle in a sample solution generates time series light intensity data of light from a light detection region detected during moving the position of the light detection region of a microscope in the sample solution and detects in the data a signal indicating light from each light-emitting particle individually. The measuring unit time is determined based on the size and the moving speed of the light detection region.

Abstract: In the optical analysis technique of detecting an existence of a single particle in a sample solution with a confocal microscope or a multiphoton microscope according to the scanning molecule counting method of the present invention, the position of a light detection region is moved in the sample solution; the light intensity from the light detection region is measured so that light intensity data will be generated; a first occurrence probability in assuming a first condition that no single particles exist in the light detection region and a second occurrence probability in assuming a second condition that a single particle exists in the light detection region for a time variation of light intensity value on the light intensity data are computed; and a signal indicating each single particle is detected based on those occurrence probabilities, and thereby enabling improvements in the sensitivity and/or S/N ratio.

Abstract: There is provided a single particle detection technique based on a scanning molecule counting method, enabling individual detection of a single particle using light measurement with a confocal or multiphoton microscope, and quantitative observation of conditions or characteristics of the particle. The inventive technique of detecting a single particle in a sample solution detects light containing substantially constant background light from a light detection region with moving the position of the light detection region of the microscope in a sample solution to generate time series light intensity data; and detects individually a light intensity reduction occurred when a single particle which does not emit light (or a particle whose emitting light intensity in a detected wavelength band is lower than the background light) enters in the light detection region in the time series light intensity data as a signal indicating the existence of each single particle.

Abstract: There is provided a structure to make the setting of a criterion for eliminating noises easy in the scanning molecule counting method. In the inventive optical analysis technique of detecting light of a light-emitting particle in a sample solution, time series light intensity data of light from a light detection region detected with moving the position of the light detection region in the sample solution is generated, and a signal of a light-emitting particle individually is detected in the time series light intensity data, wherein a signal having a light intensity in a light intensity range set based upon a signal generation frequency integrated value distribution which is a distribution, obtained by using as a variable an intensity of a signal, of integrated values of generation frequencies of signals having an intensity not lower than the variable is extracted as the signal of the light-emitting particle.