Abstract: A computerized clinical action system and method supports a comprehensive view of member health status and identification of candidates for numerous clinical actions such as health alerts and clinical interventions. The computerized system and method facilitate clinical action integration and coordination by providing the infrastructure to share key member information among clinical actions. The computerized system and method comprises a clinical guidance exchange (CGX) that receives and accesses member data from a plurality of sources to facilitate creation of integrated member profiles. The CGX further receives and accesses clinical data from a clinical data hub that integrates clinical data from numerous sources. A rules guidance exchange (RGX) facilitates the identification of candidates for clinical actions through the application of clinical and business rules.