Patents by Inventor Thaddeus J. Wadas

Thaddeus J. Wadas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR SYNTHESIS OF ALPHA-EMITTING RADIOPHARMACEUTICALS
    Publication number: 20230382819
    Abstract: The present disclosure provides processes for the preparation of alpha emitting radiopharmaceutical compositions, in particular DOTATATE complexes of alpha emitting radionuclides, as well as use of such prepared compositions in the treatment of cancers.
    Type: Application
    Filed: October 14, 2021
    Publication date: November 30, 2023
    Inventors: David L. MORSE, Thaddeus J. WADAS, Darpan PANDYA, Narges TAFRESHI, Mikalai BUDZEVICH
  • KIT TECHNOLOGY FOR THE PRODUCTION AND LONG-TERM STORAGE OF ZR-89-PET RADIOPHARMACEUTICALS
    Publication number: 20210046197
    Abstract: The present invention is directed to radiopharmaceuticals with improved stability, a kit, and a method of production thereof.
    Type: Application
    Filed: January 25, 2019
    Publication date: February 18, 2021
    Applicant: Wake Forest University
    Inventors: Thaddeus J. Wadas, Nikunj B. Bhatt, Darpan N. Pandya
  • Compounds, compositions and associated methods using zirconium-89 in immuno-positron emission tomography
    Patent number: 10758634
    Abstract: Disclosed are novel compounds, complexes, compositions and methods using Zirconium-89 combined with azamacrocyclic chelators in connection with PET. The compositions and methods should provide better diagnostic, prognostic and therapeutic oncology treatments relative to the presently available chelator compositions due to a variety of superior properties of the disclosed compositions. The present invention also relates to a superior method of making these compounds, complexes, compositions that allows one to make compounds/complexes (and thus, compositions) that were previously unattainable.
    Type: Grant
    Filed: March 18, 2017
    Date of Patent: September 1, 2020
    Assignee: Wake Forest University
    Inventors: Thaddeus J. Wadas, Darpan N. Pandya, Nikunj B. Bhatt
  • COMPOUNDS, COMPOSITIONS AND ASSOCIATED METHODS USING ZIRCONIUM-89 IN IMMUNO-POSITRON EMISSION TOMOGRAPHY
    Publication number: 20190038785
    Abstract: Disclosed are novel compounds, complexes, compositions and methods using Zirconium-89 combined with azamacrocyclic chelators in connection with PET. The compositions and methods should provide better diagnostic, prognostic and therapeutic oncology treatments relative to the presently available chelator compositions due to a variety of superior properties of the disclosed compositions. The present invention also relates to a superior method of making these compounds, complexes, compositions that allows one to make compounds/complexes (and thus, compositions) that were previously unattainable.
    Type: Application
    Filed: March 18, 2017
    Publication date: February 7, 2019
    Inventors: Thaddeus J. Wadas, Darpan N. Pandya, Nikunj B. Bhatt