Patents by Inventor Thai D. Nguyen

Thai D. Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
    Patent number: 7138511
    Abstract: In a preferred aspect of the invention, the upstream sequences of the TIGR protein encoding sequence can be used to diagnose a sensivity to steroids and a risk for glaucoma or ocular hypertensive disorders. Methods, kits, and nucleic acids containing polymorphisms, base substitutions, or base additions located within the upstream region and within protein-encoding regions of the TIGR gene are also provided. The upstream sequences disclosed, including the TIGR promoter regions and those regions possessing functional characterisitics associated with or possesssed by the TIGR gene 5?regulatory region, can also be used to generate cells, vectors, and nucleic acids useful in a variety of diagnostic and prognostic methods and kits as well as therapeutic compounds, compositions, and methods.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: November 21, 2006
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Pu Chen, Hua Chen
  • Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
    Publication number: 20030068640
    Abstract: In a preferred aspect of the invention, the upstream sequences of the TIGR protein encoding sequence can be used to diagnose a sensivity to steroids and a risk for glaucoma or ocular hypertensive disorders. Methods, kits, and nucleic acids containing polymorphisms, base substitutions, or base additions located within the upstream region and within protein-encoding regions of the TIGR gene are also provided. The upstream sequences disclosed, including the TIGR promoter regions and those regions possessing functional characteristics associated with or possessed by the TIGR gene 5′regulatory region, can also be used to generate cells, vectors, transgenic animals, and nucleic acid constructs useful in a variety of diagnostic and prognostic methods and kits as well as therapeutic compounds, compositions, and methods.
    Type: Application
    Filed: September 17, 2002
    Publication date: April 10, 2003
    Inventors: Thai D. Nguyen, Jon R. Polansky, Pu Chen, Hua Chen
  • Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
    Patent number: 6475724
    Abstract: In a preferred aspect of the invention, the upstream sequences of the TIGR protein encoding sequence can be used to diagnose a sensivity to steroids and a risk for glaucoma or ocular hypertensive disorders. Methods, kits, and nucleic acids containing polymorphisms, base substitutions, or base additions located within the upstream region and within protein-encoding regions of the TIGR gene are also provided. The upstream sequences disclosed, including the TIGR promoter regions and those regions possessing functional characteristics associated with or possessed by the TIGR gene 5′regulatory region, can also be used to generate cells, vectors, transgenic animals, and nucleic acid constructs useful in a variety of diagnostic and prognostic methods and kits as well as therapeutic compounds, compositions, and methods.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: November 5, 2002
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Pu Chen, Hua Chen
  • Trabecular meshwork induced glucocorticoid response (TIGR) fusion protein
    Patent number: 6248867
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: October 20, 1995
    Date of Patent: June 19, 2001
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
    Patent number: 6171788
    Abstract: The nucleic acid upstream of the TIGR protein encoding sequence can be used to diagnose glaucoma. Polymorphisms, base substitutions, base additions located with the upstream and within TIGR exons can also be used to diagnose glaucoma. In addition, polymorphisms, base substitutions, base additions located with the upstream and within TIGR exons can also be used to prognose glaucoma.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: January 9, 2001
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Pu Chen, Hua Chen
  • Methods for the diagnosis of glaucoma
    Patent number: 6150161
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: November 21, 2000
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Trabecular meshwork induced glucocorticoid response (TIGR) nucleic acid molecules
    Patent number: 5861497
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: January 19, 1999
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Methods for the diagnosis of glaucoma
    Patent number: 5854415
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabeclar meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: December 29, 1998
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Methods for the diagnosis of glaucoma
    Patent number: 5849879
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: May 14, 1996
    Date of Patent: December 15, 1998
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Methods for the diagnosis of glaucoma
    Patent number: 5789169
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related disease.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: August 4, 1998
    Assignee: Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang
  • Methods for the diagnosis of glaucoma
    Patent number: 5606043
    Abstract: A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
    Type: Grant
    Filed: November 3, 1994
    Date of Patent: February 25, 1997
    Assignee: The Regents of the University of California
    Inventors: Thai D. Nguyen, Jon R. Polansky, Weidong Huang