Patents by Inventor Thales Papagiannakopoulos

Thales Papagiannakopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCERS HAVING A DEREGULATED NRF2/KEAP1 PATHWAY
    Publication number: 20210361603
    Abstract: The present disclosure relates to a method of treating a subject having cancer that includes selecting a subject having cancer associated with a deregulated NRF2/KEAP1 pathway and administering to the selected subject one or more inhibitors comprising a glutamine transporter inhibitor; a GPD2 inhibitor; or combination(s) thereof.
    Type: Application
    Filed: February 6, 2018
    Publication date: November 25, 2021
    Applicants: New York University, Massachusetts Institute Of Technology
    Inventors: Thales PAPAGIANNAKOPOULOS, Tyler JACKS, Rodrigo ROMERO
  • Modulation of Oxidative Stress and Amino Acid Metabolism for the Treatment or Prevention of Diseases and Disorders
    Publication number: 20210085763
    Abstract: The present invention relates methods for treating cancer by comprising administering to the subject an agent for reducing at least one NEAA, inhibiting the PPP pathway, inhibiting the sorbitol pathway, inhibiting heme biosynthesis, or any combination thereof. The invention also includes methods of treating cancer comprising detecting a tumor as having increased ROS administering to the subject an agent for reducing at least one NEAA, inhibiting the PPP pathway, inhibiting the sorbitol pathway or inhibiting heme biosynthesis, or any combination thereof.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 25, 2021
    Inventor: Thales Papagiannakopoulos