Patents by Inventor Thanh Lam

Thanh Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260108618
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: July 23, 2025
    Publication date: April 23, 2026
    Inventors: Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Thanh LAM, Leslie W. TARI
  • Patent number: 12569565
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: March 10, 2026
    Assignee: Cidara Therapeutics, Inc.
    Inventors: James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
  • Publication number: 20260000781
    Abstract: The disclosure provides conjugates including an Fc domain monomer or Fc domain covalently linked to a moiety that binds to or inhibits CD73. The disclosure also provides pharmaceutical compositions including such conjugates and uses of such conjugates in the treatment of disorders associated with dysregulation or overexpression of CD73 (e.g., cancer, fibrosis, or a viral infection).
    Type: Application
    Filed: July 5, 2023
    Publication date: January 1, 2026
    Inventors: Allen BORCHARDT, Thomas P. BRADY, Hongyuan CHEN, Jason COLE, Ramkrishna DE, Joanne M. FORTIER, Travis James HAUSSENER, Thanh LAM, Dhanya Raveendra PANICKAR, Leslie W. TARI
  • Patent number: 12427200
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Grant
    Filed: August 15, 2022
    Date of Patent: September 30, 2025
    Assignee: Cidara Therapeutics, Inc.
    Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
  • Publication number: 20240156975
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: September 11, 2023
    Publication date: May 16, 2024
    Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
  • Patent number: 11855995
    Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.
    Type: Grant
    Filed: December 1, 2022
    Date of Patent: December 26, 2023
    Assignee: Kyndryl, Inc.
    Inventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
  • Publication number: 20230398226
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: August 15, 2022
    Publication date: December 14, 2023
    Inventors: Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Thanh LAM, Leslie W. TARI
  • Patent number: 11833213
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: December 5, 2023
    Assignee: Cidara Therapeutics, Inc.
    Inventors: James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
  • Publication number: 20230190950
    Abstract: Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 22, 2023
    Inventors: Suzanne AKERS-RODRIGUEZ, James Michael BALKOVEC, Daniel C. BENSEN, Timothy BLIZZARD, Allen BORCHARDT, Thomas Patrick BRADY, Zhi-Yong CHEN, Quyen-Quyen Thuy DO, Joanne M. FORTIER, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
  • Publication number: 20230165970
    Abstract: Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.
    Type: Application
    Filed: December 19, 2018
    Publication date: June 1, 2023
    Inventors: Suzanne AKERS-RODRIGUEZ, James M. BALKOVEC, Daniel C. BENSEN, Timothy BLIZZARD, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Joanne M. FORTIER, Wanlong JIANG, Thanh LAM, James LEVIN, Alain NONCOVICH, Leslie W. TARI
  • Publication number: 20230096158
    Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.
    Type: Application
    Filed: December 1, 2022
    Publication date: March 30, 2023
    Applicant: KYNDRYL, INC.
    Inventors: Mary E. RUDDEN, Karen CHENG, Thanh LAM, Daniel S. RILEY, Craig M. TRIM
  • Patent number: 11552955
    Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: January 10, 2023
    Assignee: Kyndryl, Inc.
    Inventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
  • Patent number: 11510992
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: November 29, 2022
    Assignee: Cidara Therapeutics, Inc.
    Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
  • Publication number: 20220257787
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: April 21, 2021
    Publication date: August 18, 2022
    Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
  • Patent number: 11093636
    Abstract: A computer-implemented method includes: receiving, by a computing device, a container from a data requester server for processing data as part of an inference analysis; attaching, by the computing device, an input data volume and an output data volume associated with the container; processing, by the computing device, input data stored in the input data volume to produce output data; attaching, by the computing device, the output data in the output data volume; detaching, by the computing device, the input data volume based on attaching the output data to the output data volume; determining, by the computing device, whether sensitive data exists in the output data volume; and providing, by the computing device, the output data volume to the data requester server based on the determining that sensitive data does not exist in the output data volume.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: August 17, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mary E. Rudden, Thanh Lam, Daniel S. Riley, Craig M. Trim, Rhonda L. Childress
  • Publication number: 20210228727
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: March 5, 2021
    Publication date: July 29, 2021
    Applicants: Cidara Therapeutics, Inc., Cidara Therapeutics, Inc.
    Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
  • Publication number: 20210220478
    Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).
    Type: Application
    Filed: March 5, 2021
    Publication date: July 22, 2021
    Applicant: Cidara Therapeutics, Inc.
    Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
  • Publication number: 20210211434
    Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.
    Type: Application
    Filed: March 24, 2021
    Publication date: July 8, 2021
    Inventors: Mary E. RUDDEN, Karen CHENG, Thanh LAM, Daniel S. RILEY, Craig M. TRIM
  • Patent number: 11019064
    Abstract: Data security across data residency restriction boundaries is provided by profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, automatically generating, based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, a container for processing the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, instantiating the generated container on a data processing system at the one location, and processing the dataset into the reformatted dataset using the instantiated generated container, and transferring the reformatted dataset to the another location.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: May 25, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
  • Publication number: 20200110896
    Abstract: A computer-implemented method includes: receiving, by a computing device, a container from a data requester server for processing data as part of an inference analysis; attaching, by the computing device, an input data volume and an output data volume associated with the container; processing, by the computing device, input data stored in the input data volume to produce output data; attaching, by the computing device, the output data in the output data volume; detaching, by the computing device, the input data volume based on attaching the output data to the output data volume; determining, by the computing device, whether sensitive data exists in the output data volume; and providing, by the computing device, the output data volume to the data requester server based on the determining that sensitive data does not exist in the output data volume.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 9, 2020
    Inventors: Mary E. Rudden, Thanh Lam, Daniel S. Riley, Craig M. Trim, Rhonda L. Childress