Patents by Inventor Thanh Lam
Thanh Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260108618Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: July 23, 2025Publication date: April 23, 2026Inventors: Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Thanh LAM, Leslie W. TARI
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Patent number: 12569565Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: September 11, 2023Date of Patent: March 10, 2026Assignee: Cidara Therapeutics, Inc.Inventors: James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
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Publication number: 20260000781Abstract: The disclosure provides conjugates including an Fc domain monomer or Fc domain covalently linked to a moiety that binds to or inhibits CD73. The disclosure also provides pharmaceutical compositions including such conjugates and uses of such conjugates in the treatment of disorders associated with dysregulation or overexpression of CD73 (e.g., cancer, fibrosis, or a viral infection).Type: ApplicationFiled: July 5, 2023Publication date: January 1, 2026Inventors: Allen BORCHARDT, Thomas P. BRADY, Hongyuan CHEN, Jason COLE, Ramkrishna DE, Joanne M. FORTIER, Travis James HAUSSENER, Thanh LAM, Dhanya Raveendra PANICKAR, Leslie W. TARI
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Patent number: 12427200Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: August 15, 2022Date of Patent: September 30, 2025Assignee: Cidara Therapeutics, Inc.Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
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Publication number: 20240156975Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: September 11, 2023Publication date: May 16, 2024Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Patent number: 11855995Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.Type: GrantFiled: December 1, 2022Date of Patent: December 26, 2023Assignee: Kyndryl, Inc.Inventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
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Publication number: 20230398226Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: August 15, 2022Publication date: December 14, 2023Inventors: Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Thanh LAM, Leslie W. TARI
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Patent number: 11833213Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: April 21, 2021Date of Patent: December 5, 2023Assignee: Cidara Therapeutics, Inc.Inventors: James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
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Publication number: 20230190950Abstract: Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.Type: ApplicationFiled: December 20, 2017Publication date: June 22, 2023Inventors: Suzanne AKERS-RODRIGUEZ, James Michael BALKOVEC, Daniel C. BENSEN, Timothy BLIZZARD, Allen BORCHARDT, Thomas Patrick BRADY, Zhi-Yong CHEN, Quyen-Quyen Thuy DO, Joanne M. FORTIER, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Publication number: 20230165970Abstract: Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.Type: ApplicationFiled: December 19, 2018Publication date: June 1, 2023Inventors: Suzanne AKERS-RODRIGUEZ, James M. BALKOVEC, Daniel C. BENSEN, Timothy BLIZZARD, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Joanne M. FORTIER, Wanlong JIANG, Thanh LAM, James LEVIN, Alain NONCOVICH, Leslie W. TARI
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Publication number: 20230096158Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.Type: ApplicationFiled: December 1, 2022Publication date: March 30, 2023Applicant: KYNDRYL, INC.Inventors: Mary E. RUDDEN, Karen CHENG, Thanh LAM, Daniel S. RILEY, Craig M. TRIM
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Patent number: 11552955Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.Type: GrantFiled: March 24, 2021Date of Patent: January 10, 2023Assignee: Kyndryl, Inc.Inventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
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Patent number: 11510992Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: April 21, 2021Date of Patent: November 29, 2022Assignee: Cidara Therapeutics, Inc.Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
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Publication number: 20220257787Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: April 21, 2021Publication date: August 18, 2022Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Patent number: 11093636Abstract: A computer-implemented method includes: receiving, by a computing device, a container from a data requester server for processing data as part of an inference analysis; attaching, by the computing device, an input data volume and an output data volume associated with the container; processing, by the computing device, input data stored in the input data volume to produce output data; attaching, by the computing device, the output data in the output data volume; detaching, by the computing device, the input data volume based on attaching the output data to the output data volume; determining, by the computing device, whether sensitive data exists in the output data volume; and providing, by the computing device, the output data volume to the data requester server based on the determining that sensitive data does not exist in the output data volume.Type: GrantFiled: October 5, 2018Date of Patent: August 17, 2021Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Mary E. Rudden, Thanh Lam, Daniel S. Riley, Craig M. Trim, Rhonda L. Childress
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Publication number: 20210228727Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: March 5, 2021Publication date: July 29, 2021Applicants: Cidara Therapeutics, Inc., Cidara Therapeutics, Inc.Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Publication number: 20210220478Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: ApplicationFiled: March 5, 2021Publication date: July 22, 2021Applicant: Cidara Therapeutics, Inc.Inventors: James M. BALKOVEC, Daniel C. BENSEN, Allen BORCHARDT, Thomas P. BRADY, Zhi-Yong CHEN, Jason COLE, Quyen-Quyen Thuy DO, Simon DOEHRMANN, Wanlong JIANG, Thanh LAM, Alain NONCOVICH, Leslie W. TARI
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Publication number: 20210211434Abstract: Data security across data residency restriction boundaries is provided by obtaining and profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, then automatically generating a container image based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, the container image configured for instantiation and execution to process the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, and storing the container image to a container registry.Type: ApplicationFiled: March 24, 2021Publication date: July 8, 2021Inventors: Mary E. RUDDEN, Karen CHENG, Thanh LAM, Daniel S. RILEY, Craig M. TRIM
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Patent number: 11019064Abstract: Data security across data residency restriction boundaries is provided by profiling a dataset on which a desired analysis is to be performed, with some results of the desired analysis to be transferred from one location to another, the dataset subject to data residency restrictions that restrict transfer of the dataset across a boundary to the another location, and the profiling identifying a profile level for the dataset, automatically generating, based on the profile level and the data residency restrictions that restrict the transfer of the dataset across the boundary, a container for processing the dataset into a reformatted dataset not restricted by the data residency restrictions for transfer across the boundary, instantiating the generated container on a data processing system at the one location, and processing the dataset into the reformatted dataset using the instantiated generated container, and transferring the reformatted dataset to the another location.Type: GrantFiled: September 4, 2018Date of Patent: May 25, 2021Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Mary E. Rudden, Karen Cheng, Thanh Lam, Daniel S. Riley, Craig M. Trim
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Publication number: 20200110896Abstract: A computer-implemented method includes: receiving, by a computing device, a container from a data requester server for processing data as part of an inference analysis; attaching, by the computing device, an input data volume and an output data volume associated with the container; processing, by the computing device, input data stored in the input data volume to produce output data; attaching, by the computing device, the output data in the output data volume; detaching, by the computing device, the input data volume based on attaching the output data to the output data volume; determining, by the computing device, whether sensitive data exists in the output data volume; and providing, by the computing device, the output data volume to the data requester server based on the determining that sensitive data does not exist in the output data volume.Type: ApplicationFiled: October 5, 2018Publication date: April 9, 2020Inventors: Mary E. Rudden, Thanh Lam, Daniel S. Riley, Craig M. Trim, Rhonda L. Childress