Abstract: Disclosed are indazole compounds and derivatives thereof for use as modulators of the activity of mitogen-activated protein kinase 4 (MEK4). The disclosed compounds include 3-arylindazoles and 3-amino-indazoles which may be formulated in pharmaceutical composition for treating cell proliferative diseases and disorders associated with MEK4 activity, including cancer.

Abstract: Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane.

Abstract: A high-density memory system includes at least one memory-dense compute unit with a printed circuit board (“PCB”) having a half-width one rack unit (“1U”) form factor, more than 20 memory module slots arranged depth-wise from a front to a rear of the PCB with a horizontal orientation that is parallel to the half-width 1U form factor, at least one processor positioned in between the memory module slots, a dripless connector with a first port that receives a cooling solution from a manifold of a cooling unit and a second port that returns the cooling solution into the manifold, tubing that extends the full length of the PCB from the first port past the memory module slots and the at least one processor and back to the second port, and cooling blocks that are located in between the memory module slots and that are connected to the tubing.

Abstract: An adapter assembly for securing a luminaire to a niche formed in a wall of a pool or spa. The assembly comprises a mounting bracket having a rear portion shaped and sized to fit within the niche and a front portion comprising a peripheral flange sized to engage the wall surrounding the niche. The mounting bracket enables the luminaire to be secured thereto and be visible from a front side thereof. The assembly includes at least one clamping device attached to the rear portion of the mounting bracket and configured to secure the mounting bracket to the niche. In a preferred embodiment, the clamping device comprises a clamping arm and drive member. The clamping arm is pivotally connected to the mounting bracket such that the mounting bracket is drawn into the niche and the peripheral flange of the mounting bracket is drawn towards the wall surrounding the niche.

Abstract: Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane.

Abstract: A spin-orbit torque (SOT) magnetic tunnel junction (MTJ) device includes a substrate, a buffer layer formed over the substrate, and a bismuth antimony (BiSb) layer formed over the buffer layer, the BiSb layer having a (012) orientation. In certain embodiments, the SOT MTJ device is part of a microwave assisted magnetic recording (MAMR) write head. In certain embodiments, the SOT MTJ device is part of a magnetoresistive random access memory (MRAM) device.

Abstract: Provided is a disaggregated memory server, which in some examples is a rack-mounted hardware appliance comprising a pool of memory for allocation to memory clients. Examples of memory clients may include one or more rack-mounted computing devices co-located on a rack with the disaggregated memory server. The disaggregated memory server may be optimized for high-speed dynamic memory allocation to the other computing devices in the rack.

Abstract: Aryl diimine first row metal compounds are described, as well as their synthesis and use as catalysts for the hydrofunctionalization of unsaturated organic compounds and main group element—main group element bond formation by dehydrogenative coupling.

Abstract: A spin-orbit torque (SOT) magnetic tunnel junction (MTJ) device includes a substrate, a seed layer over the substrate, and a bismuth antimony (BiSb) layer having (0120) orientation on the seed layer. The seed layer includes a silicide layer and a surface control layer. The silicide layer includes a material of NiSi, NiFeSi, NiFeTaSi, NiCuSi, CoSi, CoFeSi, CoFeTaSi, CoCuSi, or combinations thereof. The surface control layer includes a material of NiFe, NiFeTa, NiTa, NiW, NiFeW, NiCu, NiCuM, NiFeCu, CoTa, CoFeTa, NiCoTa, Co, CoM, CoNiM, CoNi, NiSi, CoSi, NiCoSi, Cu, CuAgM, CuM, or combinations thereof, in which M is Fe, Cu, Co, Ta, Ag, Ni, Mn, Cr, V, Ti, or Si.

Abstract: Provided is a disaggregated memory server, which in some examples is a rack-mounted hardware appliance comprising a pool of memory for allocation to memory clients. Examples of memory clients may include one or more rack-mounted computing devices co-located on a rack with the disaggregated memory server. The disaggregated memory server may be optimized for high-speed dynamic memory allocation to the other computing devices in the rack.

Abstract: Devices for assisting with the functioning of a tricuspid valve of a heart include a shaft, a flow optimizer, and an anchoring mechanism. A tilting mechanism can be configured to tilt the shaft relative to a central axis of the anchoring mechanism. Leaflets (e.g., multi-layer leaflets) of the flow optimizer can include a membrane and a rim, and the rim can have a higher stiffness than the membrane. A delivery system can be configured to deliver the device and adjust the position of the flow optimizer with respect to the anchoring mechanism.

Abstract: Disclosed is a controller for a disaggregated memory device. The controller may receive a request to allocate memory of a specific size from the disaggregated memory device to a computing device, and may generate a memory block device in the specific size from a memory pool formed from physical memory modules configured on the disaggregated memory device. The controller may expose the memory block device to the computing device as a Non-Volatile Memory Express (“NVMe”) target device, and may control access to the memory block device by converting NVMe access requests in a first format from the computing device to access requests in a different second format supported by the memory block device.

Abstract: A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween. In some embodiments, the flange structures are non-symmetrical with respect to one another. Systems and methods of using the stents are also disclosed.

Abstract: Disclosed is a controller for a disaggregated memory device. The controller may receive a request to allocate memory of a specific size from the disaggregated memory device to a computing device, and may generate a memory block device in the specific size from a memory pool formed from physical memory modules configured on the disaggregated memory device. The controller may expose the memory block device to the computing device as a Non-Volatile Memory Express (“NVMe”) target device, and may control access to the memory block device by converting NVMe access requests in a first format from the computing device to access requests in a different second format supported by the memory block device.

Abstract: Provided is a disaggregated memory server, which in some examples is a rack-mounted hardware appliance comprising a pool of memory for allocation to memory clients. Examples of memory clients may include one or more rack-mounted computing devices co-located on a rack with the disaggregated memory server. The disaggregated memory server may be optimized for high-speed dynamic memory allocation to the other computing devices in the rack.

Abstract: A spin-orbit torque (SOT) magnetic tunnel junction (MTJ) device includes a substrate, a seed layer over the substrate, and a bismuth antimony (BiSb) layer having (0120) orientation on the seed layer. The seed layer includes a silicide layer and a surface control layer. The silicide layer includes a material of NiSi, NiFeSi, NiFeTaSi, NiCuSi, CoSi, CoFeSi, CoFeTaSi, CoCuSi, or combinations thereof. The surface control layer includes a material of NiFe, NiFeTa, NiTa, NiW, NiFeW, NiCu, NiCuM, NiFeCu, CoTa, CoFeTa, NiCoTa, Co, CoM, CoNiM, CoNi, NiSi, CoSi, NiCoSi, Cu, CuAgM, CuM, or combinations thereof, in which M is Fe, Cu, Co, Ta, Ag, Ni, Mn, Cr, V, Ti, or Si.

Abstract: An adapter assembly for securing a luminaire to a niche formed in a wall of a pool or spa. The assembly comprises a mounting bracket having a rear portion shaped and sized to fit within the niche and a front portion comprising a peripheral flange sized to engage the wall surrounding the niche. The mounting bracket enables the luminaire to be secured thereto and be visible from a front side thereof. The assembly includes at least one clamping device attached to the rear portion of the mounting bracket and configured to secure the mounting bracket to the niche. In a preferred embodiment, the clamping device comprises a clamping arm and drive member. The clamping arm is pivotally connected to the mounting bracket such that the mounting bracket is drawn into the niche and the peripheral flange of the mounting bracket is drawn towards the wall surrounding the niche.

Abstract: Disclosed is a controller for providing applications seamless access to local and remote memory so that data of a particular application that is moved out of the Random Access Memory (“RAM”) of a local device may be stored and accessed in RAM of a remote device rather than on higher latency and slower performing storage mediums. The controller provides an application with a first allocation of RAM from the local device running the application, and a second allocation of RAM from the remote device. The controller registers to receive a page fault notification for a particular page that the application attempts to access and that is not stored in the first allocation of RAM. The controller retrieves the particular page from the second allocation of RAM, and loads it into the first allocation of RAM where it becomes accessible by the application.

Abstract: The present disclosure generally relates to a magnetic media drive employing a magnetic recording head. The magnetic recording head comprises a first write head, a second write head, at least one read head, and a thermal fly height control element. The first write head is a wide writing write head comprising a first main pole and a first trailing shield. The second write head a narrow writing write head comprising a second main pole, a trailing gap, a second trailing shield, and one or more side shields. The first main pole has a shorter height and a greater width than the second main pole. The second main pole has a curved or U-shaped surface disposed adjacent to the trailing gap. The thermal fly height control element and the at least one read head are aligned with a center axis of the second main pole of the second write head.

Abstract: The present disclosure generally relates to a magnetic media drive employing a magnetic recording head. The magnetic recording head comprises a first write head and a second write head each coupled to a first pad and a second pad of a slider pad and an electrical circuit coupled to the first and second pads. The first write head is a wide writing write head, and the second write head a narrow writing write head. The electrical circuit comprises a first sub-circuit and a second sub-circuit connected in parallel. The first sub-circuit comprises a capacitor and a connection to a first thermal fly height control (TFC) of the first write head. The second sub-circuit comprises an inductor and a connection to a second TFC of the second write head. The electrical circuit is further connected to a third TFC of a read head, the second write head comprising the read head.