Patents by Inventor Thashree Marimuthu

Thashree Marimuthu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermoresponsive hydrogel
    Patent number: 11197948
    Abstract: This invention relates to thermoresponsive hydrogels. Particularly, the invention relates to a thermoresponsive hydrogel comprising copolymer polyethylene glycol (PEG)-polycaprolactone (PCL)-polyethylene glycol (PEG) and polypropylene fumerate (PPF). The thermoresponsive hydrogel may further comprise a poloxamer, particularly Pluronic F-127. The invention extends to a method of manufacturing thermoresponsive hydrogels, also extends to an ink for a three dimensional (3D) printer including the thermoresponsive hydrogels. The invention further extends to a thermoresponsive hydrogel for use in the treatment of a bone injury and/or a bone defect, and/or to a method of treating a bone injury and/or a bone defect. The thermoresponsive hydrogels may include dispersed therein an active pharmaceutical ingredient (API), preferably an API falling in the Biopharmaceutics Classification System (BCS) class II, further preferably a statin type drug, most preferably simvastatin.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: December 14, 2021
    Assignee: University of the Witwatersrand, Johannesburg
    Inventors: Yahya Essop Choonara, Pierre Pavan Demarco Kondiah, Pariksha Jolene Kondiah, Pradeep Kumar, Lisa Claire Du Toit, Thashree Marimuthu, Viness Pillay
  • A Thermoresponsive Hydrogel
    Publication number: 20200054791
    Abstract: This invention relates to thermoresponsive hydrogels. Particularly, the invention relates to a thermoresponsive hydrogel comprising copolymer polyethylene glycol (PEG)-polycaprolactone (PCL)-polyethylene glycol (PEG) and polypropylene fumerate (PPF). The thermoresponsive hydrogel may further comprise a poloxamer, particularly Pluronic F-127. The invention extends to a method of manufacturing thermoresponsive hydrogels, also extends to an ink for a three dimensional (3D) printer including the thermoresponsive hydrogels. The invention further extends to a thermoresponsive hydrogel for use in the treatment of a bone injury and/or a bone defect, and/or to a method of treating a bone injury and/or a bone defect. The thermoresponsive hydrogels may include dispersed therein an active pharmaceutical ingredient (API), preferably an API falling in the Biopharmaceutics Classification System (BCS) class II, further preferably a statin type drug, most preferably simvastatin.
    Type: Application
    Filed: January 31, 2018
    Publication date: February 20, 2020
    Inventors: Yahya Essop Choonara, Pierre Pavan Demarco Kondiah, Pariksha Jolene Kondiah, Pradeep Kumar, Lisa Claire Du Toit, Thashree Marimuthu, Viness Pillay