Abstract: Treatments for prostatic disease use a urethral catheter with ports positioned outside a patient. The catheter's lumen has a cross-sectional shape and an electrode assembly with a shaft having a corresponding cross-sectional shape that interlocks with the shape of the lumen. The shaft includes a plurality of shaft channels, an extendable electrode in each channel, and a collar with a protruding flange that interfaces with a port when the electrode assembly is within the lumen. An electrode actuator controls actuation of the electrodes. The collar and actuator are interfaced via a keyed structure. A plurality of ports in the assembly interface with the lumen and project the electrodes outward through the catheter and into the prostate when actuated. The electrodes are extended in a predefined rotational orientation relative to the keyed structure. A power source is coupled to the electrodes and delivers direct current to the prostate.

Abstract: Disclosed herein are an apparatus and a method for the treatment of a prostatic disease.