Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.

Abstract: An organic electroluminescent material and a device thereof are disclosed. The organic electroluminescent material uses a compound having a novel carbazole structure, and can be used as hole blocking material, host material in an electroluminescent device. These novel compounds can provide better device performance, such as obtaining device performance of very low driving-voltage, high efficiency, and long lifetime.

Abstract: A power chip includes: a first power switch, formed in a wafer region and having a first and a second metal electrodes; a second power switch, formed in the wafer region and having a third and a fourth metal electrodes, wherein the first and second power switches respectively constitute an upper bridge arm and a lower bridge arm of a bridge circuit, and the first and second power switches are alternately arranged; and a metal region, at least including a first metal layer and a second metal layer that are stacked, each metal layer including a first to a third electrodes, and electrodes with the same voltage potential in the metal layers are electrically coupled.

Abstract: Systems and methods for network-based ultrasound imaging are provided, which can include a number of features. In some embodiments, an ultrasound imaging system images an object with three-dimensional unfocused pings and obtains digital sample sets from a plurality of receiver elements. A sub-set of the digital sample sets can be electronically transferred to a remote server, where the sub-set can be beamformed to produce a series of two-dimensional image frames. A video stream made up of the series of two-dimensional images frames can then be transferred from the remote server to a display device.

Abstract: A method is provided for checking engagement and disengagement of a parking brake finger, which selectively blocks or blocks a shaft of the transmission. A motor-driven rotary selection plate is selectively controlled to butt against the transmission casing at the two ends of its travel, and is immobilized therebetween in a first functional engagement position and in a second functional disengagement position that correspond to the Park and non Park positions of the parking brake finger when the drive motor of the plate stops exerting torque thereon. The angular movements of the plate between its abutment positions are measured and incremented using a computer to determine whether the engagement position and disengagement position of the plate that is reached every time the drive motor is stopped corresponds to a command instruction given to the motor.

Abstract: A composition comprises: a base oil; an additive comprising a copolymer comprising hydrophobic and hydrophilic units; and a drug. The copolymer may for example have a comb structure in which the hydrophobic units and hydrophilic units are pendant chains on a backbone of the copolymer. The hydrophobic units and hydrophilic units may for example comprise polydimethylsiloxane moieties and ethylene glycol residues respectively. The composition may for example be used as a tamponade or as a component for a tamponade administered to the eye. The invention is useful for solubilising and/or releasing drugs.

Abstract: A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and embedded in a PMMA gel electrolyte.

Abstract: The disclosure discloses an electrolyte and an electrochemical device thereof, and an electronic device. The electrolyte includes a compound represented by formula (I): wherein R1, R3, and R4 are each independently selected from hydrogen, a cyano group, a substituted or unsubstituted C1-12 hydrocarbon group, a substituted or unsubstituted C1-12 carboxy group, a substituted or unsubstituted C6-26 aryl group, a substituted or unsubstituted C2-12 amide group, a substituted or unsubstituted C0-12 phosphate group, a substituted or unsubstituted C0-12 sulfonyl group, a substituted or unsubstituted C0-12 siloxy group or a substituted or unsubstituted C0-12 boronate group, when being substituted, a substituent includes a halogen atom. The electrolyte of the disclosure may improve the high-temperature cycle performance and room-temperature cycle performance while reducing the internal resistance of the electrochemical device.

Abstract: A point-of-care testing (POCT) fully-automatic chemiluminescence device based on a multi-channel parallel pretreatment technology includes a support. The support is provided thereon with a reaction chamber assembly, which reciprocates linearly relative to the support. A multi-channel parallel pretreatment assembly and a photomultiplier tube (PMT) assembly are arranged on the support and are located above the reaction chamber assembly. The multi-channel parallel pretreatment assembly is configured to transfer, clean, and separate reagents in reagent strips in the reaction chamber assembly. The PMT assembly is configured to detect a luminescence value of the cleaned and separated reagents. The device does not have a liquid passage, resulting in low maintenance costs and high reliability. This realizes automatic sample addition, supports whole blood testing, and avoids carry-over.

Abstract: A computing system may include a hotspot processing engine and a hotspot prediction engine. The hotspot processing engine may be configured to access an input data set of hotspot locations on manufactured circuits of a circuit design, correlate the hotspot locations to layout data for the circuit design, and extract fragment feature vectors for the hotspot locations. The hotspot processing engine may further be configured to process the fragment feature vectors such that hotspot fragment feature vectors are a threshold percentage of the total number of feature vectors in the fragment feature vectors and provide the processed fragment feature vectors as a training set for training a machine-learning model. The hotspot prediction engine may be configured to apply the machine-learning model to characterize locations of the circuit design as a hotspot location or a non-hotspot location.

Abstract: The present disclosure relates to compositions and methods for enhancing T cell response in vivo. For example, a method of enhancing T cell response in a subject or treating a subject having cancer, the method comprising: administering an effective amount of a composition comprising modified cells to the subject having a form of cancer associated with or expressing an antigen, for example, a solid tumor antigen; and administering (1) a nucleic acid encoding the antigen, (2) additional modified cells comprising the nucleic acid or the antigen, or (3) microorganisms, for example cold viruses, comprising the nucleic acid or the antigen. In embodiments, the modified cells comprise mixed cells targeting a solid tumor antigen and a white blood cell (WBC) antigen. In embodiments, the modified cells comprise a dominant negative form of an immune checkpoint molecule (e.g., PD-1). In embodiments, the modified cells comprise an exogenous polynucleotide encoding a therapeutic agent, such as IL-12 and IFN?.

Abstract: A system can automatically adjust a virtual background used by a participant in a video conference to match lighting level conditions present in a foreground of a participant video stream captured at a participant device. The matching can be done by adjusting one or more virtual background parameters, including but not limited to, exposure, brightness, contrast, and ISO. In some implementations, the system can dynamically or automatically adjust the lighting levels of the virtual background based on changes that may occur to the lighting level of the foreground during the video conference.

Abstract: The present invention relates to novel antibodies, in particular murine monoclonal antibodies, chimeric and humanized, that are able to block specifically the human IgG receptors Fc?RIIIA (CD16A) and Fc?RIIIB (CD16B) as well as the amino and nucleic acid sequences coding for such antibodies. The invention also comprises the use of such antibodies or of fragments thereof as a medicament for the preventive and/or therapeutic treatment of diseases involving CD16, like autoimmune diseases, inflammatory disorders, allergies and infections, without inducing any adverse effects. In particular, these antibodies and fragments can prevent or treat anti-drug idiopathic thrombocytopenic purpura (ITP), rheumatoid arthritis (RA) and autoimmune hemolytic anemia (ANA).

Abstract: Systems, methods, and other embodiments associated with computer distress-call detection and authentication are described. In one embodiment, a method includes detecting a human voice in audio content of a radio signal. Speech is recognized in the human voice to transform the human voice into text and vocal metrics. Feature scores are generated that represent features of the recognized speech based at least in part on the vocal metrics. The human voice is then classified as either a hoax distress call or an authentic distress call based on the feature scores. An alert is then presented indicating that the human voice is one of the hoax distress call or the authentic distress call.

Abstract: Embodiments of the present disclosure relate to compositions and methods of enhancing lymphocytes' ability to treat cancer patients. Embodiments relate to a polynucleotide comprising a nucleic acid encoding a chimeric antigen receptor (CAR), a nucleic acid encoding an Oxygen-Dependent Degradation domain (ODD), and a nucleic acid encoding one or multiple sequences of Hypoxia-Response Element (HRE).

Abstract: Methods, systems, and devices for wireless communications are described. The method may include a user equipment (UE) receiving, from a base station, signaling configuring the UE with a semi-persistent (SP) channel state information reference signal (CSI-RS) resource set. Additionally, the UE may receive, from the base station, signaling configuring the UE to communicate using multicast signaling via a multicast downlink shared channel. The UE may receive an activation command activating the SP CSI-RS resource set. The UE may apply a rule and based on the activation command and the rule perform rate matching on the multicast downlink shared channel around either multicast or unicast resources of the CSI-RS resource set.

Abstract: The present invention regards Cooperative Intelligent Transportation Systems, C-ITS. In response to detecting at least one situation involving at least one object detected within an area monitored by the ITS, a Collective Perception Message, CPM, is generated and transmitted. The CPM comprises a reference to the at least one object and an indication to indicate that the at least one object is involved in the at least one situation.

Abstract: Pasting content from a clipboard buffer as structured tabular data. A computer system determines a data type of content within a clipboard buffer. Based on the data type of the content, the computer system identifies a tabular pattern analysis technique to apply to the content. Based on applying the tabular pattern analysis technique to the content, the computer system identifies a portion of tabular content within the content. Using a clipboard application programming interface, the computer system presents the portion of tabular content to an application as paste data that is structured as a set of rows and a set of columns.

Abstract: A computer-implemented method performed by a user device is provided. The computer-implemented method includes receiving a message including an encrypted credential from a server computer; determining a response shared secret using a private key and a server public key; decrypting the encrypted credential using the response shared secret to determine a credential; obtaining a key derivation parameter from the credential; determining a first cryptogram key using the key derivation parameter; generating a first cryptogram using the first cryptogram key; and sending the first cryptogram to a second computer.

Abstract: A method and apparatus for training an information adjustment model of a charging station, an electronic device, and a storage medium are provided. An implementation comprises: acquiring a battery charging request, and determining environment state information corresponding to each charging station in a charging station set; determining, through an initial policy network, target operational information of each charging station in the charging station set for the battery charging request, according to the environment state information; determining, through an initial value network, a cumulative reward expectation corresponding to the battery charging request according to the environment state information and the target operational information; training the initial policy network and the initial value network by using a deep deterministic policy gradient algorithm; and determining the trained policy network as an information adjustment model corresponding to each charging station.