Abstract: A method for producing the preparation containing protocatechuic acid (PCA), chlorogenic acid (CGA) and caffeic acid (CA) having a high concentration from coffee cascara comprising: (i) preparing materials; (ii) mixing the coffee cascara ingredient with the sweetener ingredient, and the water ingredient, and then sterilizing to obtain a foundation mixture; (iii) admixing the composition of complex enzyme-probiotic with the foundation mixture, then hydrolyzing to obtain a hydrolyzed mixture; (iv) admixing the composition of complex enzyme-probiotic with the hydrolyzed mixture, then fermenting to obtain a fermented mixture; (v) filtering the fermented mixture for removing the solid part, and collecting the liquid part is a fermented solution; and (vi) concentrating the fermented solution to obtain a preparation containing PCA, CGA and CA having a high concentration from coffee cascara.

Abstract: A tissue resection apparatus is provided which includes an outer tube with a helical coil disposed on a distal end. The coil is provided with a first electrode. A central tube has a distal edge profile comprising one or more surface segments. One of the surface segments includes a second electrode. The central tube is slidably disposed within the outer tube and positioned such that second electrode opposes at least a portion of the first electrode. A cutting tube is slidably disposed within the central tube and includes a cutting edge.

Abstract: A mixing unit comprising a frame, a rheology control portion, and a high-volume solids blending portion. The rheology control portion comprises means for receiving a first material from a first transfer mechanism, a dispersing/mixing system connected with the frame, and a first metering system to meter the first material from the first material receiving means to the dispersing/mixing system. The dispersing/mixing system disperses/mixes the metered first material with a fluid to form a first fluid mixture. The high-volume solids blending portion comprises means for receiving a second material from a second transfer mechanism, a solids blending system connected with the frame, and a second metering system to meter the second material from the second material receiving means to the solids blending system. The solids blending system blends the metered second material with the first fluid mixture to form a second fluid mixture.

Abstract: The present disclosure discloses a wristband nerve stimulator and a use method thereof. The wristband nerve stimulator is small in volume and wearable, and has a waterproof function. As a wristband instrument, the wristband nerve stimulator can perform treatment at any time. Furthermore, the fixed main unit and the band can be quickly mounted and removed, which is convenient to replace the band.

Abstract: An optical fiber module is attached to and detached from a host device having an optical engine and an internal optical connector optically connected to the optical engine. The optical fiber module includes a housing having a first surface exposed in a state of being attached to the host device and a second surface facing the first surface; at least one first optical connector provided on the first surface; and a second optical connector provided on the second surface and capable of being optically connected to the internal optical connector. Furthermore, the optical fiber module includes: a first optical fiber optically connecting the first optical connector and the second optical connector to each other; and a light source module supplying light to the optical engine via the second optical connector.

Abstract: A packaging substrate can include a first surface having a first mounting region of a first electronic module region and a second mounting region of a second electronic module region, the second electronic module region being adjacent to the first electronic module region. The packaging substrate can include a second opposing surface having a first electrical contacts region of the first electronic module region and a second electrical contacts region of the second electronic module region. A saw street region can extend between the first and second electronic module regions, and a saw street feature can be formed on the second opposing surface within at least a portion of the saw street region, the saw street feature comprising a solder mask layer over a metal layer and being spaced from the first and second electronic module regions.

Abstract: The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. The receptor modulators can be formulated to form pharmaceutical compositions comprising the disclosed compounds or pharmaceutically acceptable salts or prodrugs thereof. The compositions may be used for managing CXCR4 related conditions, typically prevention or treatment of viral infections abnormal cellular proliferation, retinal degeneration, inflammatory diseases, or as an immunostimulant or immunosuppressant or for managing cancer and may be administered with another active ingredient such as an antiviral agent or chemotherapeutic agent.

Abstract: A corner bracket comprising a volume of matter having n pairs of parallel faces, where n is an integer larger than 2; each face of each pair of parallel faces comprising an opening; the openings in the faces of each pair of parallel faces being joined by a cylindrical recess having a longitudinal axis perpendicular to the faces joined by the cylindrical recess; the longitudinal axis of the cylindrical recesses being arranged such that the cylindrical recesses do not intersect each other. The number n can be 3 and the volume of matter can be a cube.

Abstract: A foldable display may have a display cover layer and a flexible display panel. The foldable display may bend around a bend axis. The display panel may have an array of pixels configured to display an image through the display cover layer. The display cover layer may be formed from a layer of glass. A recess may be formed in the layer of glass that extends along the bend axis. The recess may form a flexible locally thinned portion in the layer of glass that allows the glass layer to bend about the bend axis. To ensure that the display cover layer exhibits satisfactory impact resistance during drop events, corner portions of the display cover layer and other edge portions of the display cover layer may be provided with greater thickness relative to other portions of the display cover layer outside of the locally thinned portion.

Abstract: An object of the present invention is to establish means for providing a component vaccine which can selectively or intensively induce cell-mediated immunity mainly attributable to MHC class I, and humoral immunity mainly attributable to MHC class II. The inventors have found that the object can be attained by providing a component vaccine containing, as an active ingredient, a trimer and/or a hexamer of a molecular needle carrying a peptide binding to MHC class I and/or a peptide binding to MHC class II. The inventors have also found an information acquisition method that can determine the MHC class or the like of a test peptide or a similar substance by detecting a change in secretion of a physiologically active substance such as a cytokine in a test animal which has been infected with a target microorganism.

Abstract: In some examples, an augmented reality (AR) server receives instructional data to be rendered in AR. The AR rendering server extracts multiple instruction steps from the instructional data and determines multiple spatial identifiers associated with the multiple instruction steps respectively. The multiple spatial identifiers correspond to multiple spatial objects in a real-world environment. The AR rendering server then generates AR rendering data for displaying the multiple instruction steps on an AR device at selected locations associated with the multiple spatial objects in the real-world environment. The AR rendering data is then transmitted to the AR device.

Abstract: Tissue repair systems which use knotless all-suture anchors and have the ability to lock multiple repair sutures within the anchor construct. The anchor construct includes a tension suture wrapped or looped upon itself to create an open eyelet, through which multiple repair sutures originating in soft tissue are passed. The location of the eyelet may be anywhere inside the all-suture anchor or adjacent to the exterior of the anchor body. Tensioning of the tension suture causes the eyelet to restrict movement of the repair sutures and secures them within or against the anchor body.

Abstract: Various embodiments of an apparatus, method(s), system(s) and computer program product(s) described herein are directed to a Scaling Engine. The Scaling Engine identifies a background object portrayed in a background template for a video feed. The Scaling Engine determines a background template display position for concurrent display of the background object with video feed data. The Scaling Engine generates a scaled background template by modifying a current aspect ratio of the background template with the background object set at the background display position according to a video feed aspect ratio. The Scaling Engine generates a merged video feed by merging the scaled background template with live video feed data, the merged video feed data providing an unobstructed portrayal of the identified background object.

Abstract: The invention describes to compositions useful to stabilize peracetic acid, acetic acid and hydrogen peroxide compositions with polymeric phosphonic acid resins or with 1-hydroxyethylidene-1,1,-diphosphonic acid associated with the interior surface of a container to stabilize the peracetic acid, acetic and hydrogen peroxide compositions.

Abstract: The present application provides bicyclic urea compounds that modulate the activity of JAK2, which are useful in the treatment of various diseases, including cancer.

Abstract: Radar signal detection and parameter estimation is central in passive surveillance systems, providing inputs for many information processing modules in order to detect, localize, indentify and intercept hostile targets. The proposed method for detecting radar signals and estimating their intra-pulse parameters in time-varying noisy environments consists of several stages: magnitude-squared envelopes calculation, adaptive noise floor estimation, detection statistics calculation, rising edge detection, time of arrival estimation, falling edge detection, time of departure estimation, pulse width estimation, amplitude estimation and center frequency and bandwidth estimation. Estimated intra-pulse parameters are wrapped into pulse descriptor words (PDWs) for information processing tasks, where each PDW consists of time of arrival, time of departure, pulse width, pulse amplitude, center frequency, signal bandwidth, noise floor level and additional useful information.

Abstract: A semiconductor device including a magnetic tunnel junction (MTJ) stack, a dielectric encapsulation layer surrounding vertical side surfaces of the MTJ stack, a metal encapsulation layer surrounding an upper horizontal surface and a portion of a vertical side surface of the dielectric encapsulation layer, and a dielectric surrounding a remaining portion of the vertical side surface of the dielectric encapsulation layer. A method including method includes forming a magnetic tunnel junction (MTJ) stack, forming a dielectric encapsulation layer surrounding vertical side surfaces of a top electrode, a free layer, a tunneling barrier, a reference layer and a bottom electrode of the MTJ stack, and forming a metal encapsulation layer surrounding an upper horizontal surface and a portion of a vertical side surface of the dielectric encapsulation layer.

Abstract: Contemplated antiviral/cancer treatments comprise analysis of neoepitopes from viral DNA that has integrated into the host genome, and design of immunotherapeutic agents against such neoepitopes.

Abstract: A split bolt connector can include a main body with a slot that extends between first and second ends of the main body in an axial direction, a nut configured to be threadedly movable along the slot, and an insert within the slot. The main body can define a lay-in opening along the slot to receive a conductor laterally through the main body into the slot.

Abstract: The present disclosure relates to systems and methods for testing functional vision of a subject. The systems and methods utilize a plurality of obstacle courses, a plurality of contrast levels of the obstacle courses, a plurality of illumination levels, video-recording, and a robust scoring algorithm to assess the mobility of the subject.