Abstract: Tools and techniques for the rapid, continuous, invasive and/or noninvasive measurement, estimation, and/or prediction of a patient's intracranial pressure. In an aspect, some tools and techniques can predict the onset of conditions such as herniation and/or can recommend (and, in some cases, administer) a therapeutic treatment for the patient's condition. In another aspect, some techniques employ high speed software technology that enables active, long term learning from extremely large, continually changing datasets. In some cases, this technology utilizes feature extraction, state-of-the-art machine learning and/or statistical methods to autonomously build and apply relevant models in real-time.

Abstract: Optical systems utilize waveplates to simultaneously encode information for increasing image depth of field and for providing a depth map of the imaged object or sample. These waveplates are configured to result in a focus-invariant point spread function in one focal region, and to result in point spread functions that vary as a function of range within the imaged object in a different focal region. For example, a basic compound microscope might have a specially shaped waveplate inserted at the back aperture plane of the microscope objective to manipulate the phase of the wavefront. An image formed on one side of the plane of best focus is focus invariant, and is brought into focus by a restoring algorithm. An image formed on the other side of the plane of best focus captures point spread functions comprising rings that vary with depth within the imaged object.

Abstract: A balancing circuit for a plurality of series connected cells or substrings of cells is provided. In one implementation, the balancing circuit includes a plurality of primary ports; an isolated secondary port; and one or more DC-DC converters connected between the primary ports and the isolated secondary port. Each DC-DC converter includes at least one power switch. The DC-DC converters are configured to adjust a primary port current received at one or more of the plurality of primary ports based upon a difference between a voltage at the one of the primary ports and a reference voltage. Also provided are an electrical power system including such as balancing circuit and a method of balancing a plurality of electric cell substrings using such a balancing circuit.

Abstract: Disclosed herein are (Ga1-xZnx)(N1-xOx) nanocrystals and syntheses and devices related thereto.

Abstract: A method and apparatus for gas-phase reduction/oxidation is disclosed. The apparatus includes a reactor including at least one reactor tube or containment vessel with active redox material within the reactor tube or containment vessel, a first reactant gas or vacuum for reducing the active redox material, and a second reactant gas for oxidizing the active redox material. The method may be run under substantially isothermal conditions and/or energy supplied to the apparatus may include solar energy, which may be concentrated.

Abstract: Systems and methods for liquid deposition photolithography are described. In particular, some embodiments relate to systems and methods for using photolithography to control the 2D structure of a thin layer of material (e.g., photopolymer) using various masks, projection optics and materials. In one or more embodiments, this thin layer can be manipulated by micro-fluidic techniques such that it can be formed, patterned and post-processed in a liquid environment, vastly simplifying the creation of multi-layer structures. Multiple layers are rapidly built up to create thick structures of possibly multiple materials that are currently challenging to fabricate by existing methods.

Abstract: Tools and techniques for the rapid, continuous, invasive and/or noninvasive measurement, estimation, and/or prediction of a patient's intracranial pressure. In an aspect, some tools and techniques can predict the onset of conditions such as herniation and/or can recommend (and, in some cases, administer) a therapeutic treatment for the patient's condition. In another aspect, some techniques employ high speed software technology that enables active, long term learning from extremely large, continually changing datasets. In some cases, this technology utilizes feature extraction, state-of-the-art machine learning and/or statistical methods to autonomously build and apply relevant models in real-time.

Abstract: Compositions and methods of treating a neurodegenerative disorder are disclosed herein.

Abstract: The present disclosure is for improved organic semiconductors and improved organic photovoltaics. Liquid crystalline bent-core molecules in the B4 subphase of the present disclosure may be incorporated into improved organic semiconductors. Liquid crystalline bent-core molecules in the B4 subphase of the present disclosure may be incorporated into improved organic photovoltaics that may have improved quantum efficiencies over pre-existing organic photovoltaics.

Abstract: A method has been developed for the formation of multivalent cyclic peptides. This procedure exploits on-resin peptide cyclization using a photoinitiated thiol-ene click reaction and subsequent clustering using thiol-yne photochemistry. Both reactions utilize the sulfhydrl group on natural cysteine amino acids to participate in the thiol-mediated reactions.

Abstract: The present invention provides compositions and methods for increasing the delivery (i.e., bioavailability) of a compound to an ocular cell. Such compositions and methods can be used to treat an ocular clinical condition. Typically, increased bioavailability or delivery of the compound to ocular cells is achieved by utilizing a membrane transporter.

Abstract: Micro-patterned treads for endoscopes are disclosed. In an embodiment, the treads include a micro-patterned surface and a roller engaging surface. Micro-patterned tread bearing robotic capsule endoscopes are disclosed. In one embodiment, the endoscope includes a housing, a motor, a geared drive, rollers, and at least one micro-patterned tread. Methods of fabricating closed loop treads are disclosed. In an embodiment, a method includes forming a solid layer of PDMS on one side of double-sided tape and wrapping a micro-patterned PDMS strip together with the other side of the double-sided tape. In another embodiment, a method includes forming a timing belt PDMS strip on one side of double-sided tape and a micro-patterned PDMS strip together with the other side of the double-sided tape.

Abstract: A surgical method for anterior cruciate ligament reconstruction includes creating a bone tunnel in a head of a femur of a patient. A connective tissue is inserted into the bone tunnel. A shape memory polymer plug is inserted into the bone tunnel. The plug has a first configuration for insertion and a second configuration for affixation that has a radially expanded dimension that presses the connective tissue against a side wall of the bone tunnel to affix the connective tissue in the bone tunnel. The plug changes from the first configuration to the second configuration in response to an activation temperature equal to or greater than a temperature of the femur.

Abstract: The invention includes a new photopolymerizable resin system for dental restorative materials. The resin system utilizes a thiol-ene component as the reactive diluent in dimethacrylate systems. The ternary resin system comprises a thiol monomer, an ene monomer and a dimethacrylate monomer. The system of the invention has enhanced overall functional group conversion, improved polymer mechanical properties, and reduced shrinkage stress of the ternary system when compared to either traditional dimethacrylate or thiol-ene resin systems.