Abstract: Robots, controllers, systems, and methods for microcrawler robots (e.g., with stick-slip gaited locomotion and/or with power multiplexing between actuators).

Abstract: Optical systems utilize waveplates to simultaneously encode information for increasing image depth of field and for providing a depth map of the imaged object or sample. These waveplates are configured to result in a focus-invariant point spread function in one focal region, and to result in point spread functions that vary as a function of range within the imaged object in a different focal region. For example, a basic compound microscope might have a specially shaped waveplate inserted at the back aperture plane of the microscope objective to manipulate the phase of the wavefront. An image formed on one side of the plane of best focus is focus invariant, and is brought into focus by a restoring algorithm. An image formed on the other side of the plane of best focus captures point spread functions comprising rings that vary with depth within the imaged object.

Abstract: Devices, systems, and methods for imaging and measuring deflections in structures such as railroad rail are disclosed. One exemplary embodiment relates to a vision system having a high-speed, visible-light imaging camera and an evaluation unit configured for analyzing images from the camera to detect geometric variations in the structure. In a second example, additional sensors are used to identify the wheel location(s) in the same reference frame as the measurement system. In analyzing structures such as railroad track rail, the imaging camera can be coupled to a moving rail vehicle and configured for generating images of the rail as the vehicle moves along the track.

Abstract: A multi-planar velocimetry approach to characterize 3D incompressible flows based on 2D perpendicular (or otherwise complementary) velocity fields is described. Two-dimensional velocity fields acquired on the planes are reconstructed into a 3D velocity field through interpolation and the imposition of a fluid incompressibility constraint.

Abstract: The present invention relates to antibacterial peptides and analogs thereof, e.g., originating from, derived from, isolated and/or purified from mammalian milk, that reduce, inhibit and/or prevent the growth or proliferation of a bacterial organism.

Abstract: An organic optoelectronic device (OED) includes a plurality of OED cells separated by a vapor flow barrier that extends away from a substrate surface. The vapor flow barrier partially defines an OED cell area and helps prevent stray organic material deflected away from the substrate surface during deposition from being deposited outside the cell area. An organic vapor jet (OVJ) print head can be used to deposit organic material along the vapor flow barrier and may include one or more features configured to capture some of the stray organic material. A method that includes use of vapor flow barriers and/or capturing stray organic material can facilitate high-density printing of OED cells such as OLEDs with sharply defined edges and without cross-contamination among adjacent cells.

Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.

Abstract: The embodiments disclosed herein relate to various systems and methods for determining the residual stress in polycrystalline materials.

Abstract: Secreted proteins as detection markers for insect vector and graft transmitted citrus disease are described. Method and kits for detecting the secreted proteins are provided.

Abstract: A system is disclosed in which human genomes are stored in databases or in a cloud based computer system, which is secure and private and then downloaded to personal devices for possible peer-to-peer interactions for health care applications, as well as for social and other applications. The use of the system is directed to fully sequenced genomes and includes protocols that are constructed to mimic in vitro biological tests to conduct genomic analysis instead of generic computational techniques, which tend to be impractical as they require performance of online computation over the entire genome. Three specific examples of protocols or techniques for privacy-preserving testing on fully sequenced genomes included are: 1) privacy-preserving genetic paternity testing, 2) privacy-preserving personalized medicine testing, and 3) privacy-preserving genetic compatibility testing.

Abstract: An ultrasonic communication system comprising an enclosure, a first module and a second module is described. The enclosure has an internal surface, an external surface, and defines at least one metal channel. The first module comprises an ultrasonic transceiver disposed within the enclosure. The first module is positioned on the internal surface of the enclosure and is capable of transmitting and/or receiving modulated ultrasonic waves via the metal channel. The second module is positioned on the external surface of the enclosure and is adapted to transmit and/or receive modulated ultrasonic waves from the first module via the metal channel.

Abstract: The present invention relates to methods and compositions for treating and/or preventing autoimmune and/or inflammatory disease. In particular, the present invention provides therapeutics for impairing the expansion and function of autoreactive T cells, NK cells and/or NKT cells, by modulating NKG2D.

Abstract: A 1D nanowire photodetector device includes a nanowire that is individually contacted by electrodes for applying a longitudinal electric field which drives the photocurrent. An intrinsic radial electric field to inhibits photo-carrier recombination, thus enhancing the photocurrent response. Circuits of 1D nanowire photodetectors include groups of photodetectors addressed by their individual 1D nanowire electrode contacts. Placement of 1D nanostructures is accomplished with registration onto a substrate. A substrate is patterned with a material, e.g., photoresist, and trenches are formed in the patterning material at predetermined locations for the placement of 1D nanostructures. The 1D nanostructures are aligned in a liquid suspension, and then transferred into the trenches from the liquid suspension. Removal of the patterning material places the 1D nanostructures in predetermined, registered positions on the substrate.

Abstract: Display units which can be arranged to form a single arrayed display system, thereby allowing the display of much larger images than can be shown on a single display. Each display unit can include an image display, a communication mechanism, such as a network interface card or wireless interface card, and an image display module, such as a video card and an image processor. Each display module can be configured to selectively process and display portions of large digital images.

Abstract: An electro-optic device includes a first electrode, an active layer formed over and electrically connected with the first electrode, a buffer layer formed over and electrically connected with the active layer, and a second electrode formed directly on the buffer layer. The second electrode includes a plurality of nanowires interconnected into a network of nanowires. The buffer layer provides a physical barrier between the active layer and the plurality of nanowires to prevent damage to the active layer while the second electrode is formed.

Abstract: A cascode gain stage apparatus includes an input transistor having an RF input node and a transistor output node, an output transistor having a transistor input node and an RF output node, and a DC blocking capacitor connected between the transistor input and transistor output nodes.

Abstract: A linear transform can be performed using a passive analog multi-stage charge re-use linear transform circuit. The passive analog multi-stage charge re-use linear transform circuit transforms an input analog circuit to generate a transformed analog output signal. The passive analog multi-stage charge re-use linear transform circuit may be included in a software defined radio (SDR), where the transformed analog output signal may be output to an analog-to-digital converter (ADC) of the SDR device so as to enable the ADC to perform wideband spectrum sensing. The passive analog multi-stage charge re-use linear transform circuit may also be included in a beamforming device so as to enable the device to perform spectral shifting and spatial shifting of signals. This passive analog multi-stage charge re-use linear transform circuit may promote reduced power consumption in comparison to other circuits while also supporting wideband applications at high sampling rates.

Abstract: Provided herein are methods and compounds for post-translational regulation of cytochrome P450 46A1 (CYP46A1) enzyme activity in the brain and retina. Also, a method for identifying a potential regulator of a CYP46A1 enzyme using crystal structures of the enzyme and a subsequent method for screening for a regulatory activity in the presence of CYP46A1 enzyme are provided. In addition, the regulator compounds that either inhibit or stimulate cholesterol hydroxylation by the CYP46A1 enzyme are provided. Further provided is a method of treating a pathoneurological condition associated with increased cholesterol levels in the brain and retina using the stimulatory compounds.

Abstract: The present invention provides for an organic compound comprising electron deficient unit covalently linked to two or more electron rich units. The present invention also provides for a device comprising the organic compound, such as a light-emitting diode, thin-film transistor, chemical biosensor, non-emissive electrochromic, memory device, photovoltaic cells, or the like.

Abstract: Provided herein are non-viral nucleic acid vectors, including non-viral oncovectors, that are autonomously replicating plasmids (ARPs). The non-viral nucleic acid vectors exhibit fusogenic activity and can exhibit other anti-tumor or cytotoxic activities. Also provided herein are methods and uses of the non-viral nucleic acid vectors for treating cancer.