Patents by Inventor The University of Chicago

The University of Chicago has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY ALTERED CILIATES AND USES THEREOF
    Publication number: 20130224796
    Abstract: Ciliate organisms are provided that comprise reduced proteolytic processing in granules. For example, ciliates are provided that lack detectable expression of one or more sortilin (SOR) gene product. Methods for producing such genetically altered ciliates and methods for protein production in a these organisms are also provided.
    Type: Application
    Filed: February 21, 2013
    Publication date: August 29, 2013
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventor: THE UNIVERSITY OF CHICAGO
  • METHOD OF TREATING DISORDER RELATED TO HIGH CHOLESTEROL CONCENTRATION
    Publication number: 20130210792
    Abstract: A method of treating a disorder related to a high cholesterol concentration, comprising administering to a subject in need thereof a compound of formula (I): Also disclosed are methods, kits, combinations, and compositions for treating a disorder in a subject where an activator of liver X alpha is indicated, such as in, for example, treating a high cholesterol disease.
    Type: Application
    Filed: January 24, 2013
    Publication date: August 15, 2013
    Applicant: University of Chicago
    Inventor: University of Chicago
  • METHODS AND COMPOSITIONS RELATED TO IMMUNIZING AGAINST STAPHYLOCOCCAL LUNG DISEASES AND CONDITIONS
    Publication number: 20130189249
    Abstract: Embodiments of the invention include methods and compositions useful in a vaccination strategy capable of neutralizing Hla to provide immunoprotection against S. aureus pneumonia. In certain aspects the invention includes a Hla with reduced toxicity, represented by a recombinant mutant form of Hla (HlaH35L) in which histidine 35 is convened to leucine, which can be used to abrogate the productive assembly of the toxin and protect a subject from staphylococcal pneumonia.
    Type: Application
    Filed: January 15, 2013
    Publication date: July 25, 2013
    Applicant: University of Chicago
    Inventor: University of Chicago
  • PROGNOSIS AND THERAPY PREDICTIVE MARKERS AND METHODS OF USE
    Publication number: 20130150258
    Abstract: Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
    Type: Application
    Filed: January 4, 2013
    Publication date: June 13, 2013
    Applicant: The University of Chicago
    Inventor: The University of Chicago
  • PLANT PATHOGEN RESISTANCE
    Publication number: 20130130907
    Abstract: Azelaic acid or its derivatives or analogs induce a robust and a speedier defense response against pathogens in plants. Azelaic acid treatment alone does not induce many of the known defense-related genes but activates a plant's defense signaling upon pathogen exposure.
    Type: Application
    Filed: October 22, 2012
    Publication date: May 23, 2013
    Applicants: UT-Batlelle, LLC, The University of Chicago
    Inventors: The University of Chicago, UT-Batlelle, LLC