Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.

Abstract: Provided herein is a spray nozzle and a coating system using the same, the spray nozzle and the coating system comprising a liquid nozzle injecting liquid towards a substrate; a gas nozzle for injecting gas to collide with the liquid on an injection path of the liquid to perform a primary atomization of the liquid; and a voltage supply connected to the liquid nozzle, the voltage supply for applying voltage to the liquid nozzle to generate an electric field between the liquid nozzle and substrate to perform a secondary atomization of the liquid.

Abstract: The present invention relates to novel dihydronaphthalene and naphthalene derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.

Abstract: The invention relates to fatty acid acylated salicylate derivatives; compositions comprising an effective amount of a fatty acid acylated salicylate derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a fatty acid acylated salicylate derivative.

Abstract: Provided herein are sirtuin-modulating compounds of formula (II). The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders relating to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Abstract: A wash separator comprises a vessel containing a first fluid and a second fluid whereby the second fluid has a different density from the first fluid. The first fluid (3) is immiscible with the second fluid and the first and second fluids are separated from each other by an interface. A feed stream comprising a dispersion of the first and second fluid wherein the second fluid forms a disperse phase in the form of droplets is distributed within the first fluid in the vessel forming a continuous phase. A distribution element is provided in the vessel to distribute the feed stream into the second fluid. The feed stream after having been discharged from ,the distribution element has a retention time of at most 15 minutes in the feed second fluid in the vessel.

Abstract: The invention relates to fatty acid antiviral conjugates; compositions comprising an effective amount of a fatty acid antiviral conjugate; and methods for treating or preventing a viral infection comprising the administration of an effective amount of a fatty acid antiviral conjugate.

Abstract: The present invention relates to a liquid phase process for producing indium oxide-containing layers from nonaqueous solution, in which an anhydrous composition containing at least one indium halogen alkoxide of the generic formula InX(OR)2 where R=alkyl radical and/or alkoxyalkyl radical and X=F, Cl, Br or I and at least one solvent or dispersion medium is, in the sequence of points a) to d), in anhydrous atmosphere, a) applied to the substrate, b) the composition applied to the substrate is irradiated with electromagnetic radiation of wavelength ?360 nm and c) optionally dried, and then d) converted thermally to an indium oxide-containing layer, to the layers producible by the process and to the use thereof.

Abstract: Embodiments of the present technology integrate seismic data and geologic concepts into earth model building. More specifically, exemplary embodiments provide new ways to build an earth model based on information in the seismic data and geologic concepts to use as a context to interpret the seismic data and/or to add to the earth model in regions where the seismic data is missing (e.g., either no data or no data resolvability). In some embodiments, a deterministic framework is generated for an earth models through deterministic identification of discrete geobodies. A hybrid deterministic-geostatistical earth model is generated by filling stratigraphic gaps in a deterministic framework using geostatistical information and/or seismic inversion, in accordance with some embodiments.

Abstract: Some embodiments provide systems and methods of managing enterprise resources including providing a plurality of process modules for managing resources associated with a plurality of processes, at least one of the modules using at least one processor to access a database stored on a non-transitory computer-readable storage medium. Some embodiments include providing a project and asset management module for managing at least one step of a plurality of projects including long-term planning and defining at least one project work item in a project life cycle. Some embodiments also include a resource and scheduling module for maintaining a resource database stored on a non-transitory computer-readable storage medium and for scheduling project resources. Some embodiments include a planning and reporting module, an engineering design module, and an interface module that uses at least one of the processors to interface at least two of the plurality of modules.

Abstract: Bio-regulators from a group of quaternary ammonium moieties modify a gene expression in a plant to induce enhanced growth and robustness. Such bio-regulator may be applied to seeds through coating or encapsulating, to plants through root drenching, spraying and dusting. Bio-regulators may be duel-acting; causing beneficial modification to gene expressions in desirable plants while modifying gene expression in undesirable plants, making them more susceptible to herbicides. Bio-regulators are Ester Compounds, BMIA Compounds or related salts, BMIA Compounds or related salts of those compounds.

Abstract: A pressure relief valve assembly includes a housing, a diaphragm assembly separating the housing into a sensing pressure section and a tank pressure section, the sensing pressure section configured to sense both atmospheric pressure and the pressure in the tank pressure section and the tank pressure section is configured to only sense the pressure in the tank pressure section, an orifice disposed between the sensing pressure section and the tank pressure section allowing fluid to flow in through the orifice when the pressure in the sensing pressure section is less than the pressure in the tank pressure section fluid to flow out through the orifice when the pressure in the sensing pressure section is greater than the pressure in the tank pressure section.

Abstract: Generally described are extracts and beverages with enhanced nutrients, flavors and textures and methods of making the same. Some embodiments relate to extracts and beverages produced through filtration techniques.

Abstract: An improved method and apparatus for programming advanced nanometer flash memory cells is disclosed.

Abstract: Provided herein are methods for sequestering an alkyne-presenting molecule in a sample and related sequestration reagents, compositions, methods and systems.

Abstract: Improved PMOS and NMOS transistor designs for sensing circuitry use in advanced nanometer flash memory devices are disclosed.

Abstract: Systems and methods for improving crude acetone column energy efficiency and operation are provided. The method for improving crude acetone column energy efficiency and operation can include introducing a crude acetone including acetone and phenol to a fractionation column and introducing cumene, AMS, or a combination thereof to the fractionation column. The method can include fractionating the crude acetone within the fractionation column to produce an acetone containing overhead and a phenol containing bottoms. The method can also include condensing at least a portion of the acetone containing overhead indirectly with a cool heat transfer medium to provide a condensed crude acetone product and a heated heat transfer medium, wherein the heat transfer medium includes cumene.

Abstract: An apparatus for molding articles includes a first mold carrier configured to angularly displace relative to a fixed structure from a first molding position to first accessing position and a second mold carrier traveling with the first mold carrier and configured to angularly displace relative to the first mold carrier from a second molding position to a second accessing position. The first mold carrier may be pivotably coupled to the fixed structure; the second mold carrier may be slidably and rotatably coupled to the first mold carrier. A third mold carrier may be provided, and the second mold carrier may be located between the first and third mold carriers. An articulation mechanism may be provided to control relative motion of the second mold carrier relative to the first mold carrier as the first mold carrier pivots relative to the fixed structure. A method for molding articles is also provided.

Abstract: A program development framework (PDF) is described herein which allows a user to produce a program in piecemeal fashion by successively specifying program fragments. The PDF creates a new program fragment by receiving keyword information from the user that describes a new program fragment, and then identifies context information that pertains to a programmatic context in which the new program fragment appears within the overall program being created. The PDF then generates a set of candidate program fragments that satisfy the keyword information and the context information, and ranks those candidate program fragments based on ranking information. At least part of the ranking information may be based on statistical information that is produced by analyzing a corpus of previous programs produced by one or more users. The PDF then provides the ranked program fragments to the user using various user-friendly presentation strategies.