Patents by Inventor Thea Tlsty

Thea Tlsty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer progression risk assessment by microvascular phenotype
    Patent number: 12782354
    Abstract: Repression of CD36 vasculature in stromal tissues surrounding a pre-cancerous lesion provides is indicative of increased risk of subsequent progression to invasive cancer. Methods of assessing progression risk by measuring the abundance of CD36 vasculature in stromal tissues surrounding a precancerous lesion are provided, useful for various cancer types, including for assessing the risk of DCIS progression to breast cancer. Immunohistochemical analysis methods and diagnostic thresholds are provided, as well as associated methods of treatment and diagnostic kits.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: November 3, 2026
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Thea Tlsty, Joseph Caruso, Karla Kerlikowske, Annette Molinaro, RosaAnna DeFilippis
  • Cancer Progression Risk Assessment by Microvascular Phenotype
    Publication number: 20220107321
    Abstract: Repression of CD36 vasculature in stromal tissues surrounding a pre-cancerous lesion provides is indicative of increased risk of subsequent progression to invasive cancer. Methods of assessing progression risk by measuring the abundance of CD36 vasculature in stromal tissues surrounding a precancerous lesion are provided, useful for various cancer types, including for assessing the risk of DCIS progression to breast cancer. Immunohistochemical analysis methods and diagnostic thresholds are provided, as well as associated methods of treatment and diagnostic kits.
    Type: Application
    Filed: January 16, 2020
    Publication date: April 7, 2022
    Applicant: The Regents of the University of California
    Inventors: Thea Tlsty, Joseph Caruso, Karla Kerlikowske, Annette Molinaro, RosaAnna DeFilippis