Patents by Inventor Theo De Vos

Theo De Vos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the presence or absence of methylation in a sample
    Patent number: 10731215
    Abstract: Aspects of the present invention relate to compositions and methods for providing DNA fragments from a remote sample. In particular aspects a remote sample comprising DNA is provided, DNA is isolated from the remote sample, and the isolated DNA is treated in a way which allows differentiation of methylated and unmethylated cytosine. Additional, particular embodiments provide compositions and methods for methylation analysis of DNA derived from a remote sample. Other aspects provide for compositions and methods of whole genome amplification of bisulfite treated DNA. Other aspects provide methods for determining the presence or absence of methylation of at least one cytosine, or a series of cytosines in cis, in human DNA of a blood sample, a plasma sample, a serum sample or a urine sample from a human individual.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: August 4, 2020
    Assignee: EPIGENOMICS AG
    Inventors: Matthias Ballhause, Kurt Berlin, Theo De Vos, Dimo Dietrich, Volker Liebenberg, Catherine Lofton-Day, Joe Lograsso, Jennifer Maas, Fabian Model, Matthias Schuster, Andrew Z. Sledziewski, Reimo Tetzner
  • Method and Nucleic Acids for the Analysis of Colorectal Cell Proliferative Disorders
    Publication number: 20140179563
    Abstract: The invention provides methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders as well as therapy thereof by analysis of the gene EYA4 and its promoter and regulatory sequences. The invention further provides novel nucleic acid sequences useful for the cell proliferative disorder specific analysis of said gene as well as methods, assays and kits thereof.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 26, 2014
    Applicant: Epigenomics AG
    Inventors: Peter Adorjan, Matthias Burger, Sabine Maier, Ralf Lesche, Susan Cottrell, Theo De Vos
  • Method and nucleic acids for the analysis of colorectal cell proliferative disorders
    Patent number: 8691503
    Abstract: The invention provides methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders as well as therapy thereof by analysis of the gene EYA4 and its promoter and regulatory sequences. The invention further provides novel nucleic acid sequences useful for the cell proliferative disorder specific analysis of said gene as well as methods, assays and kits thereof.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: April 8, 2014
    Assignee: Epigenomics AG
    Inventors: Peter Adorjan, Matthias Burger, Sabine Maier, Ralf Lesche, Susan Cottrell, Theo De Vos
  • METHOD FOR PROVIDING DNA FRAGMENTS DERIVED FROM A REMOTE SAMPLE
    Publication number: 20110059432
    Abstract: Aspects of the present invention relate to compositions and methods for providing DNA fragments from a remote sample. In particular aspects a remote sample comprising DNA is provided, DNA is isolated from the remote sample, and the isolated DNA is treated in a way which allows differentiation of methylated and unmethylated cytosine. Additional, particular embodiments provide compositions and methods for methylation analysis of DNA derived from a remote sample. Other aspects provide for compositions and methods of whole genome amplification of bisulfite treated DNA.
    Type: Application
    Filed: April 17, 2006
    Publication date: March 10, 2011
    Applicant: EPIGENOMICS AG
    Inventors: Matthias Ballhause, Kurt Berlin, Theo De Vos, Dimo Dietrich, Volker Liebenberg, Catherine Lofton-Day, Joe Lograsso, Jennifer Maas, Fabian Model, Matthias Schuster, Andrew Z. Sledziewski, Reimo Tetzner
  • Method and nucleic acids for the analysis of colorectal cell proliferative disorders
    Publication number: 20050003463
    Abstract: The invention provides methods and nucleic acids for detecting, differentiating or distinguishing between colon cell proliferative disorders as well as therapy thereof by analysis of the gene EYA4 and its promoter and regulatory sequences. The invention further provides novel nucleic acid sequences useful for the cell proliferative disorder specific analysis of said gene as well as methods, assays and kits thereof.
    Type: Application
    Filed: February 13, 2003
    Publication date: January 6, 2005
    Inventors: Peter Adorjan, Matthias Burger, Sabine Maier, Ralf Lesche, Susan Cottrell, Theo De Vos