Patents by Inventor Theocharis Koftis

Theocharis Koftis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR STABILIZING AN ISOTHIOCYANATE
    Publication number: 20230150932
    Abstract: The present invention relates to stable compositions comprising an isothiocyanate. It also relates to methods for stabilizing an isothiocyanate. According to the invention, sulforaphane is stabilized in the presence of fatty acids. Compositions prepared by mixing sulforaphane with certain amounts of a fatty acid or a mixture of fatty acids exhibit a stabilizing effect with respect to residual sulforaphane. It was found that such compositions can maintain sulforaphane, as expressed by % w/w, more effectively, i.e. stabilize it, compared to neat sulforaphane, under certain storage conditions. This facilitates the distribution of sulforaphane as a component to be used for industrial purposes, for example in the preparation of various products, dietary supplements, food additives, pharmaceuticals, nutraceuticals, cosmetics etc, because it makes long-term storage easier and efficient.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 18, 2023
    Inventors: V. Theocharis KOFTIS, Efstratios NEOKOSMIDIS, L. Petros GZIKIS, Sakellarios TRAKOSSAS, Savvas THYSIADIS, Theodoros PANAGIOTIDIS, Thanos AANDREOU, Elli VASTARDI, Evanthia TOLIKA, Foteini ATHANASIADOU
  • A NOVEL PROCESS FOR THE PREPARATION OF TAPENTADOL
    Publication number: 20210253513
    Abstract: The present invention relates to a novel process for the preparation of Tapentadol and intermediate compound 2R,3R)-3-(-methoxyphenyl)-N,N,2-trimethylpentanamine (compound of formula IIa).
    Type: Application
    Filed: June 10, 2019
    Publication date: August 19, 2021
    Applicant: PHARMATHEN S.A.
    Inventors: V. Theocharis KOFTIS, Efstratios NEOKOSMIDIS, Christos STATHAKIS, Petros GKIZIS, Theodoros PANAGIOTIDIS
  • Process for preparing biodegradable polymers of high molecular weight
    Patent number: 11046810
    Abstract: A novel method for the preparation of biodegradable polymers is disclosed. The method produces polymers of high molecular weight and particularly allows for stirring throughout the polymerization reaction.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: June 29, 2021
    Assignee: PHARMATHEN S.A.
    Inventors: V. Theocharis Koftis, Efstratios Neokosmidis, Konstantina Karidi, Anastasia-Aikaterini Varvogli
  • PROCESS FOR PREPARING BIODEGRADABLE POLYMERS OF HIGH MOLECULAR WEIGHT
    Publication number: 20190315913
    Abstract: A novel method for the preparation of biodegradable polymers is disclosed. The method produces polymers of high molecular weight and particularly allows for stirring throughout the polymerization reaction.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 17, 2019
    Applicant: PHARMATHEN S.A.
    Inventors: V. THEOCHARIS KOFTIS, EFSTRATIOS NEOKOSMIDIS, KONSTANTINA KARIDI, ANASTASIA-AIKATERINI VARVOGLI
  • PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES
    Publication number: 20100094055
    Abstract: The present invention relates to an improved process for the preparation of essentially pure Venlafaxine Hydrochloride. Particularly, the process for the preparation of Venlafaxine Hydrochloride comprises the following steps: i) Preparation of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol, ii) Preparation of crude Venlafaxine Hydrochloride by reduction of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol with Alkali metal borohydride and Lewis acid and subsequent conversion to Venalfaxine hydrochloride with formic acid and paraformaldehyde and finally iii) Purification of crude Venlafaxine Hydrochloride.
    Type: Application
    Filed: January 9, 2007
    Publication date: April 15, 2010
    Applicant: PHARMATHEN S.A.
    Inventors: Rohit Ravikant Soni, Theocharis Koftis, Theodoros Panagiotidis, Ioanna Georgopoulou